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- W1972510109 abstract "Patients receiving chemotherapy are at an increased risk of venous thromboembolism. For sedentary patients in hospital, prophylaxis with low-molecular-weight heparins is provided, but such prevention is not routine in ambulatory patients who remain at risk. However, positive news of a once-daily anticoagulant for this indication has emerged. On Feb 16, 2012, Giancarlo Agnelli (University of Perugia, Italy) and colleagues reported the findings of a randomised placebo-controlled trial of semuloparin, an ultra-low-molecular-weight heparin, in patients receiving chemotherapy for solid tumours. After a median of 3·5 months, patients treated with 20 mg subcutaneous semuloparin had a 64% decrease in venous thromboembolism compared with controls (hazard ratio 0·36, 95% CI 0·21–0·60)." @default.
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- W1972510109 date "2012-04-01" @default.
- W1972510109 modified "2023-09-26" @default.
- W1972510109 title "Semuloparin for thromboprophylaxis during chemotherapy" @default.
- W1972510109 doi "https://doi.org/10.1016/s1470-2045(12)70079-7" @default.
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