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- W1972524014 abstract "Ageing and long-standing arterial hypertension produce almost indistinguishable pathoanatomical changes in the major target organs such as the brain, the heart and the kidneys. Arterial hypertension seems, therefore, to set the biological clock of the vascular tree at a faster pace. Left ventricular hypertrophy, nephrosclerosis and cerebral vascular damage can be found in elderly normotensive subjects but are greatly accelerated in patients with essential hypertension. Arterial compliance is reduced with age and long-standing hypertension, leading to a disproportionate increase in systolic blood pressure. Arterial compliance may become reduced to the degree that it interferes with accurate blood pressure estimation by cuff, a phenomenon known as pseudohypertension. Antihypertensive therapy should not only lower arterial pressure but improve vascular compliance and prevent target organ disease or allow existing target organ damage to regress." @default.
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- W1972524014 date "1987-11-01" @default.
- W1972524014 modified "2023-10-18" @default.
- W1972524014 title "The effects of ageing and arterial hypertension on the heart and arterial compliance" @default.
- W1972524014 doi "https://doi.org/10.1097/00001573-198711001-00005" @default.
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