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- W1972564295 abstract "In order to validate measurement of urinary sulphatoxymelatonin as an accurate method of estimating plasma melatonin secretion in older people, we compared 24 h plasma melatonin secretion and sulphatoxymelatonin excretion with renal function in 20 subjects 62-89 years of age. There was a good correlation between plasma and urinary sulphatoxymelatonin over the same 24 h period (R2 = 0.797) and no relationship between creatinine clearance and sulphatoxymelatonin excretion (R2 = 0.075). The results suggest that sulphatoxymelatonin excretion estimation is a good surrogate measurement of plasma melatonin secretion in older people, at least across the range of creatinine clearance for the subjects in the study, 0.41-1.81 ml/sec." @default.
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- W1972564295 date "1998-01-01" @default.
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- W1972564295 title "Sulphatoxymelatonin excretion in older people: Relationship to plasma melatonin and renal function" @default.
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- W1972564295 doi "https://doi.org/10.1111/j.1600-079x.1998.tb00366.x" @default.
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