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• W1972596169 abstract "RationaleThe prevalence of asthma is increasing worldwide. There are several cross sectional and longitudinal studies showing obesity or increased body mass index appears to increase th risk of asthma, wheezing and bronchial hyperresponsiveness (BHR) in adults. We investigated the association of each body composition in addition to body mass index with BHR.MethodsThis study involved a retrospective review of existing records of 234 subjects with respiratoy symptoms, who underwent pulmonary function test, methacholine challenge test and body composition test from January 2002 to August 2006.ResultsOf the 234 subjects, 113(48%) were female. The median age was 47 years for females and 36 years for males. There was no significantly difference of body mass index, fat mass and fat free mass between BHR negative group and positive group in male. But In female, Body mass index was 23.2 Kg/m2 and 25.2 Kg/m2 in BHR negative group and positive group (p < 0.05). Fat mass percent was 29.1% and 34.3% in bronchial BHR negative group and positive group (p < 0.05). Fat free mass percent was 70.3% and 65.8% in BHR negative group and positive group (p < 0.05).ConclusionsThis study showed significant differences in body mass index, fat mass and fat free mass between BHR negative group and positive group in female. But there was no significant difference in male. Increased BHR is strongly associated with fat mass and fat free mass in addition to body mass index in women. RationaleThe prevalence of asthma is increasing worldwide. There are several cross sectional and longitudinal studies showing obesity or increased body mass index appears to increase th risk of asthma, wheezing and bronchial hyperresponsiveness (BHR) in adults. We investigated the association of each body composition in addition to body mass index with BHR. The prevalence of asthma is increasing worldwide. There are several cross sectional and longitudinal studies showing obesity or increased body mass index appears to increase th risk of asthma, wheezing and bronchial hyperresponsiveness (BHR) in adults. We investigated the association of each body composition in addition to body mass index with BHR. MethodsThis study involved a retrospective review of existing records of 234 subjects with respiratoy symptoms, who underwent pulmonary function test, methacholine challenge test and body composition test from January 2002 to August 2006. This study involved a retrospective review of existing records of 234 subjects with respiratoy symptoms, who underwent pulmonary function test, methacholine challenge test and body composition test from January 2002 to August 2006. ResultsOf the 234 subjects, 113(48%) were female. The median age was 47 years for females and 36 years for males. There was no significantly difference of body mass index, fat mass and fat free mass between BHR negative group and positive group in male. But In female, Body mass index was 23.2 Kg/m2 and 25.2 Kg/m2 in BHR negative group and positive group (p < 0.05). Fat mass percent was 29.1% and 34.3% in bronchial BHR negative group and positive group (p < 0.05). Fat free mass percent was 70.3% and 65.8% in BHR negative group and positive group (p < 0.05). Of the 234 subjects, 113(48%) were female. The median age was 47 years for females and 36 years for males. There was no significantly difference of body mass index, fat mass and fat free mass between BHR negative group and positive group in male. But In female, Body mass index was 23.2 Kg/m2 and 25.2 Kg/m2 in BHR negative group and positive group (p < 0.05). Fat mass percent was 29.1% and 34.3% in bronchial BHR negative group and positive group (p < 0.05). Fat free mass percent was 70.3% and 65.8% in BHR negative group and positive group (p < 0.05). ConclusionsThis study showed significant differences in body mass index, fat mass and fat free mass between BHR negative group and positive group in female. But there was no significant difference in male. Increased BHR is strongly associated with fat mass and fat free mass in addition to body mass index in women. This study showed significant differences in body mass index, fat mass and fat free mass between BHR negative group and positive group in female. But there was no significant difference in male. Increased BHR is strongly associated with fat mass and fat free mass in addition to body mass index in women." @default.
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• W1972596169 date "2008-02-01" @default.
• W1972596169 modified "2023-09-27" @default.
• W1972596169 title "Association Of Body Composition With Bronchial Hyperresponsiveness" @default.
• W1972596169 doi "https://doi.org/10.1016/j.jaci.2007.12.313" @default.
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