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- W1972603016 abstract "Gastrointestinal stromal tumor (GIST), which is associated with mutations in KIT or a platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), is the most common mesenchymal tumor of the gastrointestinal tract[1]. A definitive diagnosis of GIST is important to ensure administration of effective drugs, such as imatinib mesylate, and immmunohistochemical staining for c-Kit or DOG1 is useful for the diagnosis. According to previous studies, cytokeratin (CK) expression is a rare event in GISTs[2-6], so they can easily be misdiagnosed as other epithelial or epithelioid mesenchymal tumors. In such cases, a diagnosis of GIST can be made when DOG1 immunoreactivity or mutation of KIT or PDGFRA are observed." @default.
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- W1972603016 date "2014-10-27" @default.
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- W1972603016 title "Cytokeratin-Positive Gastrointestinal Stromal Tumor of Biphasic Morphology: A Case Report" @default.
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- W1972603016 doi "https://doi.org/10.4132/koreanjpathol.2014.48.5.375" @default.
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