Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972605783> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W1972605783 abstract "MHC class Ⅱ has long been known to play a classical role in antigen presentation and to act as a signal transducer capable of inducing the adaptive immunity needed to produce pathogen specific antibodies. However, it has recently been revealed that MHC class Ⅱ can also promote the activation of Toll-like receptor mediated signaling by functioning as an adapter. This means that in addition to its classical function of adaptive immunity, MHC class Ⅱalso plays an intriguing role in the mechanisms that regulate innate immunity. That being the case, queries inevitably arise regarding the fact that many pathogens have tried to control the induction of MHC class Ⅱ so as to escape the host immune response. Liu et al (Nat Immunol 2011;12:416-424) demonstrated that intracellular MHC class Ⅱ interacted with Btk, and that this activated Btk promoted TLR signaling via Myd88 and TRIF. The results of this study provide insight regarding the possibility of a novel role for MHC class Ⅱ, which was heretofore regarded solely as a classical molecule involved in adaptive immune responses, as a regulator of innate immune responses." @default.
- W1972605783 created "2016-06-24" @default.
- W1972605783 creator A5016916086 @default.
- W1972605783 creator A5043727560 @default.
- W1972605783 date "2011-01-01" @default.
- W1972605783 modified "2023-10-06" @default.
- W1972605783 title "Regulation of Innate Immunity via MHC Class II-mediated Signaling; Non-classical Role of MHC Class II in Innate Immunity" @default.
- W1972605783 cites W1959729040 @default.
- W1972605783 cites W2003438808 @default.
- W1972605783 cites W2012589576 @default.
- W1972605783 cites W2024015921 @default.
- W1972605783 cites W2039683293 @default.
- W1972605783 cites W2072115152 @default.
- W1972605783 cites W2085262116 @default.
- W1972605783 cites W2086506655 @default.
- W1972605783 doi "https://doi.org/10.4167/jbv.2011.41.3.205" @default.
- W1972605783 hasPublicationYear "2011" @default.
- W1972605783 type Work @default.
- W1972605783 sameAs 1972605783 @default.
- W1972605783 citedByCount "4" @default.
- W1972605783 countsByYear W19726057832021 @default.
- W1972605783 crossrefType "journal-article" @default.
- W1972605783 hasAuthorship W1972605783A5016916086 @default.
- W1972605783 hasAuthorship W1972605783A5043727560 @default.
- W1972605783 hasConcept C136449434 @default.
- W1972605783 hasConcept C170627219 @default.
- W1972605783 hasConcept C193419808 @default.
- W1972605783 hasConcept C203014093 @default.
- W1972605783 hasConcept C207936829 @default.
- W1972605783 hasConcept C2776709828 @default.
- W1972605783 hasConcept C2778814158 @default.
- W1972605783 hasConcept C2779341262 @default.
- W1972605783 hasConcept C43929388 @default.
- W1972605783 hasConcept C86803240 @default.
- W1972605783 hasConcept C8891405 @default.
- W1972605783 hasConcept C95444343 @default.
- W1972605783 hasConceptScore W1972605783C136449434 @default.
- W1972605783 hasConceptScore W1972605783C170627219 @default.
- W1972605783 hasConceptScore W1972605783C193419808 @default.
- W1972605783 hasConceptScore W1972605783C203014093 @default.
- W1972605783 hasConceptScore W1972605783C207936829 @default.
- W1972605783 hasConceptScore W1972605783C2776709828 @default.
- W1972605783 hasConceptScore W1972605783C2778814158 @default.
- W1972605783 hasConceptScore W1972605783C2779341262 @default.
- W1972605783 hasConceptScore W1972605783C43929388 @default.
- W1972605783 hasConceptScore W1972605783C86803240 @default.
- W1972605783 hasConceptScore W1972605783C8891405 @default.
- W1972605783 hasConceptScore W1972605783C95444343 @default.
- W1972605783 hasLocation W19726057831 @default.
- W1972605783 hasOpenAccess W1972605783 @default.
- W1972605783 hasPrimaryLocation W19726057831 @default.
- W1972605783 hasRelatedWork W1192653976 @default.
- W1972605783 hasRelatedWork W1974902267 @default.
- W1972605783 hasRelatedWork W1975064863 @default.
- W1972605783 hasRelatedWork W1995615243 @default.
- W1972605783 hasRelatedWork W1998934764 @default.
- W1972605783 hasRelatedWork W2016814206 @default.
- W1972605783 hasRelatedWork W2021157543 @default.
- W1972605783 hasRelatedWork W2051483094 @default.
- W1972605783 hasRelatedWork W2054748024 @default.
- W1972605783 hasRelatedWork W2077878598 @default.
- W1972605783 hasRelatedWork W2102737028 @default.
- W1972605783 hasRelatedWork W2150745128 @default.
- W1972605783 hasRelatedWork W2154709330 @default.
- W1972605783 hasRelatedWork W2160675434 @default.
- W1972605783 hasRelatedWork W2161426250 @default.
- W1972605783 hasRelatedWork W2313980758 @default.
- W1972605783 hasRelatedWork W2368827040 @default.
- W1972605783 hasRelatedWork W2381627911 @default.
- W1972605783 hasRelatedWork W2748098899 @default.
- W1972605783 hasRelatedWork W636731300 @default.
- W1972605783 isParatext "false" @default.
- W1972605783 isRetracted "false" @default.
- W1972605783 magId "1972605783" @default.
- W1972605783 workType "article" @default.