FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972677148> ?p ?o ?g. }

• W1972677148 endingPage "508" @default.
• W1972677148 startingPage "503" @default.
• W1972677148 abstract "Summary Background 5‐alpha‐reductase inhibitors (5 ARI s) are the potent androgen responsible for the development and enlargement of the prostate gland by decreasing dihydrotestosterone ( DHT ). This results in inhibition of the conversion of testosterone to dihydrotestosterone and markedly suppresses serum dihydrotestosterone levels. Testosterone replacement therapy improves bone density in men with hypogonadal osteoporosis. This study explores the possible association between the use of two typical 5 ARI s (finasteride and dutasteride) and the subsequent risk of osteoporosis diagnosis. Methods We identified 1352 osteoporosis diagnosis cases and 5387 control cases without osteoporosis diagnosis from the claims data for patients with benign prostate hyperplasia ( BPH ), which are collected in the Taiwanese National Health Insurance Research Database ( NHIRD ). Four controls were frequency matched to each case according to age (every 5 years) and diagnosis date. We measured the effect of 5 ARI s and determined the adjusted odds ratios ( OR s) with 95% confidence intervals ( CI s). Results We observed a 1·52‐fold increase in osteoporosis diagnosis among patients with BPH using finasteride (95% CI , 1·01–2·30). Furthermore, a dosage analysis showed that higher doses of finasteride were associated with higher osteoporosis diagnosis risk ( OR = 1·68; 95% CI , 1·01–2·81), relative to the patients not using 5 ARI s. Conclusion This population‐based nested case–control study suggests that the use of finasteride can increase the risk of osteoporosis diagnosis among patients with BPH . The effects were more prominent in patients using higher doses of finasteride." @default.
• W1972677148 created "2016-06-24" @default.
• W1972677148 creator A5002542282 @default.
• W1972677148 creator A5016529967 @default.
• W1972677148 creator A5030616630 @default.
• W1972677148 creator A5038473989 @default.
• W1972677148 creator A5049940988 @default.
• W1972677148 creator A5074856859 @default.
• W1972677148 date "2014-11-04" @default.
• W1972677148 modified "2023-09-27" @default.
• W1972677148 title "A population-based nested case-control study: the use of 5-alpha-reductase inhibitors and the increased risk of osteoporosis diagnosis in patients with benign prostate hyperplasia" @default.
• W1972677148 cites W107210901 @default.
• W1972677148 cites W1490557273 @default.
• W1972677148 cites W1971032926 @default.
• W1972677148 cites W1971529801 @default.
• W1972677148 cites W1998306384 @default.
• W1972677148 cites W1999798294 @default.
• W1972677148 cites W2020105514 @default.
• W1972677148 cites W2020730609 @default.
• W1972677148 cites W2030497095 @default.
• W1972677148 cites W2042565581 @default.
• W1972677148 cites W2075116170 @default.
• W1972677148 cites W2081251422 @default.
• W1972677148 cites W2086593756 @default.
• W1972677148 cites W2121759271 @default.
• W1972677148 cites W2139372640 @default.
• W1972677148 cites W2142478998 @default.
• W1972677148 cites W2155877918 @default.
• W1972677148 cites W2156215080 @default.
• W1972677148 cites W2162405033 @default.
• W1972677148 cites W2164968437 @default.
• W1972677148 cites W2492689002 @default.
• W1972677148 cites W2804551733 @default.
• W1972677148 cites W4233555444 @default.
• W1972677148 cites W4249589997 @default.
• W1972677148 cites W4324125119 @default.
• W1972677148 doi "https://doi.org/10.1111/cen.12599" @default.
• W1972677148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25158777" @default.
• W1972677148 hasPublicationYear "2014" @default.
• W1972677148 type Work @default.
• W1972677148 sameAs 1972677148 @default.
• W1972677148 citedByCount "23" @default.
• W1972677148 countsByYear W19726771482014 @default.
• W1972677148 countsByYear W19726771482015 @default.
• W1972677148 countsByYear W19726771482016 @default.
• W1972677148 countsByYear W19726771482017 @default.
• W1972677148 countsByYear W19726771482018 @default.
• W1972677148 countsByYear W19726771482019 @default.
• W1972677148 countsByYear W19726771482020 @default.
• W1972677148 countsByYear W19726771482021 @default.
• W1972677148 countsByYear W19726771482022 @default.
• W1972677148 countsByYear W19726771482023 @default.
• W1972677148 crossrefType "journal-article" @default.
• W1972677148 hasAuthorship W1972677148A5002542282 @default.
• W1972677148 hasAuthorship W1972677148A5016529967 @default.
• W1972677148 hasAuthorship W1972677148A5030616630 @default.
• W1972677148 hasAuthorship W1972677148A5038473989 @default.
• W1972677148 hasAuthorship W1972677148A5049940988 @default.
• W1972677148 hasAuthorship W1972677148A5074856859 @default.
• W1972677148 hasConcept C121608353 @default.
• W1972677148 hasConcept C126322002 @default.
• W1972677148 hasConcept C126894567 @default.
• W1972677148 hasConcept C134018914 @default.
• W1972677148 hasConcept C156957248 @default.
• W1972677148 hasConcept C165617652 @default.
• W1972677148 hasConcept C2775874879 @default.
• W1972677148 hasConcept C2776235491 @default.
• W1972677148 hasConcept C2776541429 @default.
• W1972677148 hasConcept C2776886416 @default.
• W1972677148 hasConcept C2777083390 @default.
• W1972677148 hasConcept C2777562237 @default.
• W1972677148 hasConcept C2777911890 @default.
• W1972677148 hasConcept C2778878792 @default.
• W1972677148 hasConcept C2779279991 @default.
• W1972677148 hasConcept C2779881493 @default.
• W1972677148 hasConcept C2780435053 @default.
• W1972677148 hasConcept C2908647359 @default.
• W1972677148 hasConcept C2910366748 @default.
• W1972677148 hasConcept C29456083 @default.
• W1972677148 hasConcept C71315377 @default.
• W1972677148 hasConcept C71924100 @default.
• W1972677148 hasConcept C99454951 @default.
• W1972677148 hasConceptScore W1972677148C121608353 @default.
• W1972677148 hasConceptScore W1972677148C126322002 @default.
• W1972677148 hasConceptScore W1972677148C126894567 @default.
• W1972677148 hasConceptScore W1972677148C134018914 @default.
• W1972677148 hasConceptScore W1972677148C156957248 @default.
• W1972677148 hasConceptScore W1972677148C165617652 @default.
• W1972677148 hasConceptScore W1972677148C2775874879 @default.
• W1972677148 hasConceptScore W1972677148C2776235491 @default.
• W1972677148 hasConceptScore W1972677148C2776541429 @default.
• W1972677148 hasConceptScore W1972677148C2776886416 @default.
• W1972677148 hasConceptScore W1972677148C2777083390 @default.
• W1972677148 hasConceptScore W1972677148C2777562237 @default.
• W1972677148 hasConceptScore W1972677148C2777911890 @default.
• W1972677148 hasConceptScore W1972677148C2778878792 @default.
• W1972677148 hasConceptScore W1972677148C2779279991 @default.
• W1972677148 hasConceptScore W1972677148C2779881493 @default.

• next