FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972687616> ?p ?o ?g. }

• W1972687616 endingPage "16" @default.
• W1972687616 startingPage "8" @default.
• W1972687616 abstract "Background: The alcohol deprivation effect (ADE) is a temporary increase in the ratio of ethanol/total fluid intake and the voluntary intake of ethanol solutions over baseline drinking conditions when ethanol access is reinstated after a period of alcohol deprivation. The ADE has been posited to be an animal model for alcohol craving. The current study examined the effects of initial deprivation length and number of deprivation exposures on the ADE in alcohol-preferring (P) rats. Methods: Adult female P rats received 24-hr free-choice access to 10% (v/v) ethanol and water for 6 weeks. Rats were then randomly assigned to five groups deprived of ethanol for O (control), 2, 4, 6, or 8 weeks (W). All deprived groups were then given 24-hr access to ethanol for 2 weeks before bbeing deprived of ethanol for another 2 weeks. Results: After the initial ethanol deprivation period, the deprived groups displayed a similar 2-fold ADE (e.g., 4-W group; 4.6 ± 0.5 for baseline vs. 10.5 ± 0.3 g/kg/day for the 1st reinstatement day) during the initial 24-hr period. Ethanol consumption began to return to control levels 48 (7.1 ± 0.4 g/kg/day) and 72 (6.4 ± 0.4 g/kg/day) hrs later. In addition, each deprived group showed increases in the ratio of ethanol/total fluid intake upon reinstatement, and there was a tendency for sustained higher ethanol intake ratlos during the first 3 postexposure days for the 4-, 6-, and 8-W grups, but only during the first 2 reinstatement days for the 2-W group. The second deprivation did not increase the magnitude of the ADE over that observed in the first deprivation during the initial 24-hr period of re-exposure, but it did prolong the duration of the ADE into the 2nd and 3rd reinstatement day for the 2-, 4-, and 6-W groups and into the 5th reinstatement day for the 8-W group. Conclusions: Equivalent robust ADEs can be seen in P rats with deprivation periods of 2–8 W, which suggests that the ADE has a rapid onset and is not affected by the durations of deprivation that were tested. The duration of the ADE was prolonged in P rats exposed to a second deprivation period, suggesting that factors associated with the ADE phenomenon could be strengthened by repated deprivations." @default.
• W1972687616 created "2016-06-24" @default.
• W1972687616 creator A5017242154 @default.
• W1972687616 creator A5024757186 @default.
• W1972687616 creator A5029275926 @default.
• W1972687616 creator A5036789705 @default.
• W1972687616 creator A5074035943 @default.
• W1972687616 creator A5076405210 @default.
• W1972687616 creator A5088726928 @default.
• W1972687616 date "2000-01-01" @default.
• W1972687616 modified "2023-10-18" @default.
• W1972687616 title "Alcohol Deprivation Effect Is Prolonged in the Alcohol Preferring (P) Rat After Repeated Deprivations" @default.
• W1972687616 cites W1678524661 @default.
• W1972687616 cites W1966836222 @default.
• W1972687616 cites W1970559480 @default.
• W1972687616 cites W1971253434 @default.
• W1972687616 cites W1972853037 @default.
• W1972687616 cites W1973420255 @default.
• W1972687616 cites W1977498657 @default.
• W1972687616 cites W1986588693 @default.
• W1972687616 cites W1989098266 @default.
• W1972687616 cites W1991839015 @default.
• W1972687616 cites W1993808771 @default.
• W1972687616 cites W1994963087 @default.
• W1972687616 cites W1996646070 @default.
• W1972687616 cites W2000275624 @default.
• W1972687616 cites W2013907526 @default.
• W1972687616 cites W2015870731 @default.
• W1972687616 cites W2022451773 @default.
• W1972687616 cites W2028722367 @default.
• W1972687616 cites W2043098405 @default.
• W1972687616 cites W2051658991 @default.
• W1972687616 cites W2063692436 @default.
• W1972687616 cites W2064282880 @default.
• W1972687616 cites W2064323618 @default.
• W1972687616 cites W2064533425 @default.
• W1972687616 cites W2070250054 @default.
• W1972687616 cites W2074679739 @default.
• W1972687616 cites W2078246752 @default.
• W1972687616 cites W2078578213 @default.
• W1972687616 cites W2087771949 @default.
• W1972687616 cites W2089237550 @default.
• W1972687616 cites W2094614798 @default.
• W1972687616 cites W2120714805 @default.
• W1972687616 cites W2121734550 @default.
• W1972687616 cites W2135932086 @default.
• W1972687616 cites W2146359809 @default.
• W1972687616 cites W2153866192 @default.
• W1972687616 cites W2158666090 @default.
• W1972687616 cites W2279564409 @default.
• W1972687616 cites W2302191871 @default.
• W1972687616 cites W2408886236 @default.
• W1972687616 cites W4237982778 @default.
• W1972687616 cites W4242202017 @default.
• W1972687616 doi "https://doi.org/10.1111/j.1530-0277.2000.tb04546.x" @default.
• W1972687616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10656186" @default.
• W1972687616 hasPublicationYear "2000" @default.
• W1972687616 type Work @default.
• W1972687616 sameAs 1972687616 @default.
• W1972687616 citedByCount "102" @default.
• W1972687616 countsByYear W19726876162012 @default.
• W1972687616 countsByYear W19726876162013 @default.
• W1972687616 countsByYear W19726876162014 @default.
• W1972687616 countsByYear W19726876162015 @default.
• W1972687616 countsByYear W19726876162016 @default.
• W1972687616 countsByYear W19726876162017 @default.
• W1972687616 countsByYear W19726876162018 @default.
• W1972687616 countsByYear W19726876162019 @default.
• W1972687616 countsByYear W19726876162020 @default.
• W1972687616 countsByYear W19726876162021 @default.
• W1972687616 countsByYear W19726876162022 @default.
• W1972687616 crossrefType "journal-article" @default.
• W1972687616 hasAuthorship W1972687616A5017242154 @default.
• W1972687616 hasAuthorship W1972687616A5024757186 @default.
• W1972687616 hasAuthorship W1972687616A5029275926 @default.
• W1972687616 hasAuthorship W1972687616A5036789705 @default.
• W1972687616 hasAuthorship W1972687616A5074035943 @default.
• W1972687616 hasAuthorship W1972687616A5076405210 @default.
• W1972687616 hasAuthorship W1972687616A5088726928 @default.
• W1972687616 hasConcept C118552586 @default.
• W1972687616 hasConcept C126322002 @default.
• W1972687616 hasConcept C134018914 @default.
• W1972687616 hasConcept C140793950 @default.
• W1972687616 hasConcept C185592680 @default.
• W1972687616 hasConcept C2778555786 @default.
• W1972687616 hasConcept C2779541405 @default.
• W1972687616 hasConcept C2780161600 @default.
• W1972687616 hasConcept C2781066024 @default.
• W1972687616 hasConcept C3018430727 @default.
• W1972687616 hasConcept C48856860 @default.
• W1972687616 hasConcept C55493867 @default.
• W1972687616 hasConcept C71924100 @default.
• W1972687616 hasConcept C86803240 @default.
• W1972687616 hasConceptScore W1972687616C118552586 @default.
• W1972687616 hasConceptScore W1972687616C126322002 @default.
• W1972687616 hasConceptScore W1972687616C134018914 @default.
• W1972687616 hasConceptScore W1972687616C140793950 @default.
• W1972687616 hasConceptScore W1972687616C185592680 @default.

• next