Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972710554> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1972710554 endingPage "502" @default.
- W1972710554 startingPage "490" @default.
- W1972710554 abstract "In the available in vivo experimental models for cochlear neuronal degeneration, the peripheral (hair cell side) process of the cochlear nerve has been injured in order to induce neuronal degeneration. However, there has been no dependable experimental model in which cochlear neuronal degeneration begins from the central (brain stem side) process. This lack of a central process injury model has probably been due to the experimental difficulties that had to be overcome in order to reproducibly and selectively injure the central process of the cochlear neurons while maintaining the patency of the internal auditory artery in small experimental animals such as rats. Using rats, we first developed a central process injury model in which the reduction of the spiral ganglion cells due to retrograde degeneration of cochlear neurons can be quantitatively evaluated. In our experimental model, the cochlear nerve was compressed and injured by a compression-recording (CR) electrode placed at the internal auditory meatus. First, the cochlear nerve was compressed until the compound action potentials of the cochlear nerve became flat, and then the CR electrode was advanced by various compression speeds (5, 10, or 200 micrometer/s) to reach the same depth (400 micrometer). In our model, therefore, the reduction of the spiral ganglion cells was caused compression speed dependently. This method made it possible to produce compression injury to the cochlear nerve without evidence of damage to the blood supply to the cochlea via the internal auditory artery. This model gives us the means to obtain knowledge that was previously impossible to derive from the peripheral process injury models." @default.
- W1972710554 created "2016-06-24" @default.
- W1972710554 creator A5042290830 @default.
- W1972710554 creator A5064691879 @default.
- W1972710554 creator A5073493119 @default.
- W1972710554 creator A5088883651 @default.
- W1972710554 date "2000-02-01" @default.
- W1972710554 modified "2023-10-15" @default.
- W1972710554 title "An in Vivo Quantifiable Model of Cochlear Neuronal Degeneration Induced by Central Process Injury" @default.
- W1972710554 cites W1480973386 @default.
- W1972710554 cites W1522965955 @default.
- W1972710554 cites W1557808140 @default.
- W1972710554 cites W1967958656 @default.
- W1972710554 cites W1967985701 @default.
- W1972710554 cites W1974799194 @default.
- W1972710554 cites W1975605257 @default.
- W1972710554 cites W1981349494 @default.
- W1972710554 cites W1991355436 @default.
- W1972710554 cites W2008803709 @default.
- W1972710554 cites W2009071202 @default.
- W1972710554 cites W2011246835 @default.
- W1972710554 cites W2014699192 @default.
- W1972710554 cites W2036599049 @default.
- W1972710554 cites W2036671046 @default.
- W1972710554 cites W2038914534 @default.
- W1972710554 cites W2046130807 @default.
- W1972710554 cites W2050138141 @default.
- W1972710554 cites W2061063067 @default.
- W1972710554 cites W2077595616 @default.
- W1972710554 cites W2091193005 @default.
- W1972710554 cites W2095389793 @default.
- W1972710554 cites W2126790009 @default.
- W1972710554 cites W2153032414 @default.
- W1972710554 cites W2319658589 @default.
- W1972710554 doi "https://doi.org/10.1006/exnr.1999.7280" @default.
- W1972710554 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10686071" @default.
- W1972710554 hasPublicationYear "2000" @default.
- W1972710554 type Work @default.
- W1972710554 sameAs 1972710554 @default.
- W1972710554 citedByCount "34" @default.
- W1972710554 countsByYear W19727105542012 @default.
- W1972710554 countsByYear W19727105542015 @default.
- W1972710554 countsByYear W19727105542018 @default.
- W1972710554 countsByYear W19727105542019 @default.
- W1972710554 crossrefType "journal-article" @default.
- W1972710554 hasAuthorship W1972710554A5042290830 @default.
- W1972710554 hasAuthorship W1972710554A5064691879 @default.
- W1972710554 hasAuthorship W1972710554A5073493119 @default.
- W1972710554 hasAuthorship W1972710554A5088883651 @default.
- W1972710554 hasConcept C105702510 @default.
- W1972710554 hasConcept C111919701 @default.
- W1972710554 hasConcept C142724271 @default.
- W1972710554 hasConcept C169760540 @default.
- W1972710554 hasConcept C2776796419 @default.
- W1972710554 hasConcept C2779152698 @default.
- W1972710554 hasConcept C2779354088 @default.
- W1972710554 hasConcept C2780130748 @default.
- W1972710554 hasConcept C41008148 @default.
- W1972710554 hasConcept C71924100 @default.
- W1972710554 hasConcept C86803240 @default.
- W1972710554 hasConcept C98045186 @default.
- W1972710554 hasConceptScore W1972710554C105702510 @default.
- W1972710554 hasConceptScore W1972710554C111919701 @default.
- W1972710554 hasConceptScore W1972710554C142724271 @default.
- W1972710554 hasConceptScore W1972710554C169760540 @default.
- W1972710554 hasConceptScore W1972710554C2776796419 @default.
- W1972710554 hasConceptScore W1972710554C2779152698 @default.
- W1972710554 hasConceptScore W1972710554C2779354088 @default.
- W1972710554 hasConceptScore W1972710554C2780130748 @default.
- W1972710554 hasConceptScore W1972710554C41008148 @default.
- W1972710554 hasConceptScore W1972710554C71924100 @default.
- W1972710554 hasConceptScore W1972710554C86803240 @default.
- W1972710554 hasConceptScore W1972710554C98045186 @default.
- W1972710554 hasFunder F4320320912 @default.
- W1972710554 hasIssue "2" @default.
- W1972710554 hasLocation W19727105541 @default.
- W1972710554 hasLocation W19727105542 @default.
- W1972710554 hasOpenAccess W1972710554 @default.
- W1972710554 hasPrimaryLocation W19727105541 @default.
- W1972710554 hasRelatedWork W1981405419 @default.
- W1972710554 hasRelatedWork W2018951393 @default.
- W1972710554 hasRelatedWork W2088285235 @default.
- W1972710554 hasRelatedWork W2144432076 @default.
- W1972710554 hasRelatedWork W2350714470 @default.
- W1972710554 hasRelatedWork W2368540579 @default.
- W1972710554 hasRelatedWork W2377270718 @default.
- W1972710554 hasRelatedWork W2393551401 @default.
- W1972710554 hasRelatedWork W2912252933 @default.
- W1972710554 hasRelatedWork W4385620401 @default.
- W1972710554 hasVolume "161" @default.
- W1972710554 isParatext "false" @default.
- W1972710554 isRetracted "false" @default.
- W1972710554 magId "1972710554" @default.
- W1972710554 workType "article" @default.