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- W1972729755 abstract "We identified a Drosophila melanogaster gene encoding a peptide that dramatically decreases spontaneous muscle contractions and, correspondingly, named the peptide flatline (FLT). This gene consisted of 4 exons and was cytologically localized to 32D2-3. Processing of a predicted 122 amino acid precursor would release pEVRYRQCYFNPISCF that differs from Manduca sexta allatostatin (Mas-AST) by one amino acid, Y4-->F4. FLT does not act as an allatostatin. In situ tissue hybridization further suggests FLT is a novel brain-gut peptide and specifically, the measured activity indicates that it is a potent myotropin. Despite its profound myotropic effect, pupae injected with FLT eclosed." @default.
- W1972729755 created "2016-06-24" @default.
- W1972729755 creator A5067189790 @default.
- W1972729755 date "2002-04-01" @default.
- W1972729755 modified "2023-10-11" @default.
- W1972729755 title "Drosophila melanogaster flatline encodes a myotropin orthologue to Manduca sexta allatostatin" @default.
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- W1972729755 doi "https://doi.org/10.1016/s0196-9781(01)00649-0" @default.
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