Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972776399> ?p ?o ?g. }
- W1972776399 endingPage "140" @default.
- W1972776399 startingPage "132" @default.
- W1972776399 abstract "We have analyzed one of the nine complementation groups that constitute the haplolethal (HL) region of the Shaker gene complex (ShC). Five mutations, including a dominant lethal, define this complementation group: HL I. Mutant phenotypes show abnormal embryogenesis with structural defects in the nervous system and aberrant degeneration of specific adult muscles in addition to altered action potentials. HL I encodes a family of proteins with extensive homology to invertebrate troponin I (TnI). Members of this family are brought about by two alternative and two mutually exclusive exons in conjunction with two differential polyadenylation sites. Transcription analysis indicates that some isoforms are adult specific and others are synthesized throughout development, except during early metamorphosis. Certain isoforms of Drosophila TnI are expressed in specific muscles. The specificity of mutant phenotypes suggests a functional role of particular TnI isoforms in the development and the mature activity of muscle and nervous systems." @default.
- W1972776399 created "2016-06-24" @default.
- W1972776399 creator A5002046837 @default.
- W1972776399 creator A5020451832 @default.
- W1972776399 creator A5023669976 @default.
- W1972776399 creator A5053443643 @default.
- W1972776399 creator A5071615457 @default.
- W1972776399 creator A5083891200 @default.
- W1972776399 creator A5089299214 @default.
- W1972776399 date "1991-01-01" @default.
- W1972776399 modified "2023-09-25" @default.
- W1972776399 title "Troponin I is encoded in the haplolethal region of the Shaker gene complex of Drosophila." @default.
- W1972776399 cites W1515802281 @default.
- W1972776399 cites W1578752164 @default.
- W1972776399 cites W1585690069 @default.
- W1972776399 cites W1590429718 @default.
- W1972776399 cites W1947481567 @default.
- W1972776399 cites W1954284565 @default.
- W1972776399 cites W1982558048 @default.
- W1972776399 cites W1986119019 @default.
- W1972776399 cites W2000439492 @default.
- W1972776399 cites W2002554363 @default.
- W1972776399 cites W2005393972 @default.
- W1972776399 cites W2006287346 @default.
- W1972776399 cites W2009105413 @default.
- W1972776399 cites W2011921542 @default.
- W1972776399 cites W2014669590 @default.
- W1972776399 cites W2015292449 @default.
- W1972776399 cites W2021304032 @default.
- W1972776399 cites W2022996031 @default.
- W1972776399 cites W2032706017 @default.
- W1972776399 cites W2040324704 @default.
- W1972776399 cites W2047423425 @default.
- W1972776399 cites W2063985696 @default.
- W1972776399 cites W2069724528 @default.
- W1972776399 cites W2071713643 @default.
- W1972776399 cites W2079127507 @default.
- W1972776399 cites W2087844645 @default.
- W1972776399 cites W2089458125 @default.
- W1972776399 cites W2105540085 @default.
- W1972776399 cites W2109175971 @default.
- W1972776399 cites W2138270253 @default.
- W1972776399 cites W2169905193 @default.
- W1972776399 cites W2415509487 @default.
- W1972776399 cites W4254469900 @default.
- W1972776399 cites W4294216491 @default.
- W1972776399 cites W98634603 @default.
- W1972776399 doi "https://doi.org/10.1101/gad.5.1.132" @default.
- W1972776399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1899228" @default.
- W1972776399 hasPublicationYear "1991" @default.
- W1972776399 type Work @default.
- W1972776399 sameAs 1972776399 @default.
- W1972776399 citedByCount "52" @default.
- W1972776399 countsByYear W19727763992016 @default.
- W1972776399 countsByYear W19727763992019 @default.
- W1972776399 countsByYear W19727763992020 @default.
- W1972776399 countsByYear W19727763992021 @default.
- W1972776399 countsByYear W19727763992023 @default.
- W1972776399 crossrefType "journal-article" @default.
- W1972776399 hasAuthorship W1972776399A5002046837 @default.
- W1972776399 hasAuthorship W1972776399A5020451832 @default.
- W1972776399 hasAuthorship W1972776399A5023669976 @default.
- W1972776399 hasAuthorship W1972776399A5053443643 @default.
- W1972776399 hasAuthorship W1972776399A5071615457 @default.
- W1972776399 hasAuthorship W1972776399A5083891200 @default.
- W1972776399 hasAuthorship W1972776399A5089299214 @default.
- W1972776399 hasBestOaLocation W19727763991 @default.
- W1972776399 hasConcept C104317684 @default.
- W1972776399 hasConcept C127716648 @default.
- W1972776399 hasConcept C142575336 @default.
- W1972776399 hasConcept C143065580 @default.
- W1972776399 hasConcept C150194340 @default.
- W1972776399 hasConcept C188082640 @default.
- W1972776399 hasConcept C36823959 @default.
- W1972776399 hasConcept C53345823 @default.
- W1972776399 hasConcept C54355233 @default.
- W1972776399 hasConcept C5911399 @default.
- W1972776399 hasConcept C86803240 @default.
- W1972776399 hasConcept C95444343 @default.
- W1972776399 hasConceptScore W1972776399C104317684 @default.
- W1972776399 hasConceptScore W1972776399C127716648 @default.
- W1972776399 hasConceptScore W1972776399C142575336 @default.
- W1972776399 hasConceptScore W1972776399C143065580 @default.
- W1972776399 hasConceptScore W1972776399C150194340 @default.
- W1972776399 hasConceptScore W1972776399C188082640 @default.
- W1972776399 hasConceptScore W1972776399C36823959 @default.
- W1972776399 hasConceptScore W1972776399C53345823 @default.
- W1972776399 hasConceptScore W1972776399C54355233 @default.
- W1972776399 hasConceptScore W1972776399C5911399 @default.
- W1972776399 hasConceptScore W1972776399C86803240 @default.
- W1972776399 hasConceptScore W1972776399C95444343 @default.
- W1972776399 hasIssue "1" @default.
- W1972776399 hasLocation W19727763991 @default.
- W1972776399 hasLocation W19727763992 @default.
- W1972776399 hasOpenAccess W1972776399 @default.
- W1972776399 hasPrimaryLocation W19727763991 @default.
- W1972776399 hasRelatedWork W1507023994 @default.
- W1972776399 hasRelatedWork W1519902998 @default.