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• W1972809227 abstract "Acta Psychiatrica ScandinavicaVolume 50, Issue 4 p. 410-424 CLOZAPINE AND HALOPERIDOL IN A SINGLE-BLIND CROSS-OVER TRIAL: THERAPEUTIC AND BIOCHEMICAL ASPECTS IN THE TREATMENT OF SCHIZOPHRENIA J. Gerlach, J. Gerlach Departments E and H (Heads: I. Munkvad, M.D., R. Fog, M.D., P. Kristjansen, M.D., and P. Udsen, M.D.), St. Hans Hospital, Roskilde, DenmarkSearch for more papers by this authorP. Koppelhus, P. Koppelhus Departments E and H (Heads: I. Munkvad, M.D., R. Fog, M.D., P. Kristjansen, M.D., and P. Udsen, M.D.), St. Hans Hospital, Roskilde, DenmarkSearch for more papers by this authorE. Helweg, E. Helweg Departments E and H (Heads: I. Munkvad, M.D., R. Fog, M.D., P. Kristjansen, M.D., and P. Udsen, M.D.), St. Hans Hospital, Roskilde, DenmarkSearch for more papers by this authorA. Monrad, A. Monrad Departments E and H (Heads: I. Munkvad, M.D., R. Fog, M.D., P. Kristjansen, M.D., and P. Udsen, M.D.), St. Hans Hospital, Roskilde, DenmarkSearch for more papers by this author J. Gerlach, J. Gerlach Departments E and H (Heads: I. Munkvad, M.D., R. Fog, M.D., P. Kristjansen, M.D., and P. Udsen, M.D.), St. Hans Hospital, Roskilde, DenmarkSearch for more papers by this authorP. Koppelhus, P. Koppelhus Departments E and H (Heads: I. Munkvad, M.D., R. Fog, M.D., P. Kristjansen, M.D., and P. Udsen, M.D.), St. Hans Hospital, Roskilde, DenmarkSearch for more papers by this authorE. Helweg, E. Helweg Departments E and H (Heads: I. Munkvad, M.D., R. Fog, M.D., P. Kristjansen, M.D., and P. Udsen, M.D.), St. Hans Hospital, Roskilde, DenmarkSearch for more papers by this authorA. Monrad, A. Monrad Departments E and H (Heads: I. Munkvad, M.D., R. Fog, M.D., P. Kristjansen, M.D., and P. Udsen, M.D.), St. Hans Hospital, Roskilde, DenmarkSearch for more papers by this author First published: August 1974 https://doi.org/10.1111/j.1600-0447.1974.tb09706.xCitations: 146AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References Andén, N.-E., B.-E. Roos & B. Werdinius (1963): On the occurrence of homovanillic acid in brain and cerebrospinal fluid and its determination by a fluorometric method. Life Sci. 7, 448– 458. Andén, N.-E., & G. Stock (1973): Effect of clozapine on the turnover of dopamine in the corpus striatum and in the limbic system. J. Pharm. Pharmacol. 25, 346– 348. Angst, J., U. Jaenicke, A. Padrutt & Ch. Scharfetter (1971): Ergebnisse eines Doppelblindversuches von HF 1854 (8-chlor-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e) (1,4)diazepin) im Vergleich zu Levomepromazin. Pharmakopsychiat. 4, 192– 200. Bartholini, G., W. Haefely, M. Jalfre, H. H. Keller & A. Pletscher (1972): Effects of clozapine on cerebral catecholaminergic neurone systems. Brit. J. Pharmacol. 46, 736– 740. Bartholini, G., H. H. Keller & A. Pletscher (1973): Effect of neuroleptics on endogenous norepinephrine in rat brain. Neuropharmacology 12, 751– 756. Costall, B., & R. J. Naylor (1973): Neuroleptic and non-neuroleptic catalepsy. Arzneimittel-Forsch. (Drug Res.) 23, 674– 683. Fog, R. (1974): Neuroleptic action of clozapine injected into various brain areas in rats. J. Pharmacol. 5, Suppl. 2, 32. Gauch, R., & W. Michaelis (1971): The metabolism of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e) (1,4)diazepine (clozapine) in mice, dogs and human subjects. Farmaco, Ed. prat. 26, 667– 681. Gross, H., & E. Kaltenbäck (1970): Results of a double-blind comparison of clozapine and thioridazine. Presented at the C.I.N.P. VII Congress, Prague , August 11–15. Haase, H. J., & P. A. J. Janssen (1965): The action of neuroleptic drugs. Year Book Publisher, Inc., Chicago . Hyttel, J. (1974): Effect of neuroleptics on the disappearance rate of 14C labelled catecholamines formed from 14C-tyrosine in mouse brain. J. Pharm. Pharmacol. 26, 588– 596. Janssen, P. A. J. (1966): The chemical anatomy of neuroleptic drugs. Farm. Rev. (Stockh.). 65, 272– 294. Janssen, P. A. J. (1970): Chemical and pharmacological classification of neuroleptics. In D. P. Bobon, P. A. J. Janssen & J. Bobon, (eds.): Modern problems of pharmacopsychiatry The neuroleptics Vol. 5. S. Karger, Basel, pp. 33– 44. Keller, H. H., G. Bartholini & A. Pletscher (1973): Increase of 3-methoxy-4-hydroxyphenyl-ethylene glycol in rat brain by neuroleptic drugs. Europ. J. Pharmacol. 23, 183– 186. Lindt, S., H. Lauener & E. Eichenberger (1971): The toxicology of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e,) (1,4)diazepine (clozapine). Farmaco, Ed. prat. 26, 585– 602. Overall, J. E., & D. R. Gorham (1962): The brief psychiatric rating scale. Psychol. Reports 10, 799– 812. Randrup, A., & I. Munkvad (1972): Evidence indicating an association between schizophrenia and dopaminergic hyperactivity in the brain. Orthomol. Psychiat. 1, 2– 7. Raskin, D. E. (1972): Akathisia: A side effect to be remembered. Amer. J. Psychiat. 129, 121– 123. Schmutz, J., F. Hunziker, G. Stille & H. Lauener (1967): Constitution chimique et action pharmacologique d'un nouveau groupe de neuroleptiques tricycliques. 11. communication sur des hétérosycles à 7 atomes Bull. Chim. thér 6, 424– 429. Sedvall, G., & H. Nybäck (1972): Neuroleptikabehandling vid schizofreni. Nord. psykiat. T. 26, 323– 340. Stille, G., & H. Hippius (1971): Kritische Stellungnahme zum Begriff der Neuroleptika (anhand von pharmakologischen und klinischen Befunden mit Clozapin). Pharmakopsychiat. 4, 182– 191. Stille, G., H. Lauener & E. Eichenberger (1971): The pharmacology of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e) (1,4)diazepine (clozapine). Farmaco, Ed. prat. 26, 603– 625. Walter, E. (1970): Statistische Methoden I. (Lecture notes.) Springer-Verlag, Berlin , pp. 324– 328. Winer, B. (1970): Statistical principles in experiment design. Mc-Graw-Hill, London , pp. 302– 312. Citing Literature Volume50, Issue4August 1974Pages 410-424 ReferencesRelatedInformation" @default.
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