FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972817744> ?p ?o ?g. }

• W1972817744 endingPage "140" @default.
• W1972817744 startingPage "135" @default.
• W1972817744 abstract "Cerebral venous ischemia can result in severe brain edema. Inhibition of vascular endothelial growth factor (VEGF) activity by a neutralizing antibody can completely block the hypoxia-induced increase in vascular permeability. VEGF, which induces angiogenesis, also acts as a vascular permeability (VP) factor. We previously showed that inhibition of VEGF attenuates VP and reduces cerebral venous infarction (CVI) in the acute stage. The present study investigated the therapeutic time window during which inhibition of VEGF can reduce CVI in a rat two-vein occlusion (2-VO) model. A 2-VO model was created by photochemically occluding two adjacent cortical veins. Male Wistar rats (n = 42) were assigned to one of four groups: Group 1 was treated with a VEGF antagonist at 24 hours after 2-VO (n = 11); Group 2 was treated with phosphate-buffered solution (PBS) at 24 hours after 2-VO (n = 11); Group 3 was treated with a VEGF antagonist at 48 hours after 2-VO (n = 10); and Group 4 was treated with PBS at 48 hours after 2-VO (n = 10). The developing ischemic infarct was evaluated histologically at 7 days after 2-VO. CVI areas were significantly smaller in Group 1 than in Groups 2, 3, and 4 (p <0.05) but were similar when comparing Groups 3 and 4. Anti-VEGF therapy was effective in reducing CVI in rats if started within 24 hours after 2-VO." @default.
• W1972817744 created "2016-06-24" @default.
• W1972817744 creator A5002468717 @default.
• W1972817744 creator A5041954417 @default.
• W1972817744 creator A5047241681 @default.
• W1972817744 creator A5060268134 @default.
• W1972817744 creator A5063373940 @default.
• W1972817744 creator A5078888657 @default.
• W1972817744 creator A5080351529 @default.
• W1972817744 date "2013-01-01" @default.
• W1972817744 modified "2023-09-24" @default.
• W1972817744 title "Post-ischemic Administration of Vascular Endothelial Growth Factor Inhibitor in a Rat Model of Cerebral Venous Infarction" @default.
• W1972817744 cites W1962154683 @default.
• W1972817744 cites W1966293423 @default.
• W1972817744 cites W1969328947 @default.
• W1972817744 cites W1972875007 @default.
• W1972817744 cites W1983628010 @default.
• W1972817744 cites W1985712533 @default.
• W1972817744 cites W1987278634 @default.
• W1972817744 cites W1987522740 @default.
• W1972817744 cites W1991007651 @default.
• W1972817744 cites W1994014733 @default.
• W1972817744 cites W2001500938 @default.
• W1972817744 cites W2002851005 @default.
• W1972817744 cites W2015615473 @default.
• W1972817744 cites W2036264929 @default.
• W1972817744 cites W2039348509 @default.
• W1972817744 cites W2044300547 @default.
• W1972817744 cites W2082329504 @default.
• W1972817744 cites W2084498863 @default.
• W1972817744 cites W2086121277 @default.
• W1972817744 cites W2089762529 @default.
• W1972817744 cites W2109472836 @default.
• W1972817744 cites W2109726055 @default.
• W1972817744 cites W2126643924 @default.
• W1972817744 cites W2151327193 @default.
• W1972817744 cites W2166050160 @default.
• W1972817744 cites W310193716 @default.
• W1972817744 cites W4250593330 @default.
• W1972817744 cites W99677479 @default.
• W1972817744 doi "https://doi.org/10.2176/nmc.53.135" @default.
• W1972817744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23524495" @default.
• W1972817744 hasPublicationYear "2013" @default.
• W1972817744 type Work @default.
• W1972817744 sameAs 1972817744 @default.
• W1972817744 citedByCount "5" @default.
• W1972817744 countsByYear W19728177442017 @default.
• W1972817744 countsByYear W19728177442018 @default.
• W1972817744 countsByYear W19728177442019 @default.
• W1972817744 countsByYear W19728177442023 @default.
• W1972817744 crossrefType "journal-article" @default.
• W1972817744 hasAuthorship W1972817744A5002468717 @default.
• W1972817744 hasAuthorship W1972817744A5041954417 @default.
• W1972817744 hasAuthorship W1972817744A5047241681 @default.
• W1972817744 hasAuthorship W1972817744A5060268134 @default.
• W1972817744 hasAuthorship W1972817744A5063373940 @default.
• W1972817744 hasAuthorship W1972817744A5078888657 @default.
• W1972817744 hasAuthorship W1972817744A5080351529 @default.
• W1972817744 hasBestOaLocation W19728177441 @default.
• W1972817744 hasConcept C113045295 @default.
• W1972817744 hasConcept C126322002 @default.
• W1972817744 hasConcept C126894567 @default.
• W1972817744 hasConcept C134018914 @default.
• W1972817744 hasConcept C167734588 @default.
• W1972817744 hasConcept C170493617 @default.
• W1972817744 hasConcept C178790620 @default.
• W1972817744 hasConcept C185592680 @default.
• W1972817744 hasConcept C2776885963 @default.
• W1972817744 hasConcept C2777025900 @default.
• W1972817744 hasConcept C2777202286 @default.
• W1972817744 hasConcept C2780394083 @default.
• W1972817744 hasConcept C2780886150 @default.
• W1972817744 hasConcept C42219234 @default.
• W1972817744 hasConcept C540031477 @default.
• W1972817744 hasConcept C541997718 @default.
• W1972817744 hasConcept C71924100 @default.
• W1972817744 hasConcept C7836513 @default.
• W1972817744 hasConceptScore W1972817744C113045295 @default.
• W1972817744 hasConceptScore W1972817744C126322002 @default.
• W1972817744 hasConceptScore W1972817744C126894567 @default.
• W1972817744 hasConceptScore W1972817744C134018914 @default.
• W1972817744 hasConceptScore W1972817744C167734588 @default.
• W1972817744 hasConceptScore W1972817744C170493617 @default.
• W1972817744 hasConceptScore W1972817744C178790620 @default.
• W1972817744 hasConceptScore W1972817744C185592680 @default.
• W1972817744 hasConceptScore W1972817744C2776885963 @default.
• W1972817744 hasConceptScore W1972817744C2777025900 @default.
• W1972817744 hasConceptScore W1972817744C2777202286 @default.
• W1972817744 hasConceptScore W1972817744C2780394083 @default.
• W1972817744 hasConceptScore W1972817744C2780886150 @default.
• W1972817744 hasConceptScore W1972817744C42219234 @default.
• W1972817744 hasConceptScore W1972817744C540031477 @default.
• W1972817744 hasConceptScore W1972817744C541997718 @default.
• W1972817744 hasConceptScore W1972817744C71924100 @default.
• W1972817744 hasConceptScore W1972817744C7836513 @default.
• W1972817744 hasIssue "3" @default.
• W1972817744 hasLocation W19728177441 @default.
• W1972817744 hasLocation W19728177442 @default.

• next