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• W1972863886 abstract "RNA interference (RNAi) has been employed as an effective tool for studying gene functions. Here, we have demonstrated that different short hairpin RNAs (shRNAs) can specifically knock-down the transcription of STAT6, resulting in the inhibition of cell proliferation, G1/S phase arrest and apoptotic death in colon cancer HT-29 cells. These findings suggest that Stat6 signaling pathway plays a role in the regulation of cell proliferation and apoptosis in colon cancer cells, which promises further investigation for targeted cancer therapy." @default.
• W1972863886 created "2016-06-24" @default.
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• W1972863886 date "2006-11-01" @default.
• W1972863886 modified "2023-09-24" @default.
• W1972863886 title "STAT6 specific shRNA inhibits proliferation and induces apoptosis in colon cancer HT-29 cells" @default.
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• W1972863886 doi "https://doi.org/10.1016/j.canlet.2005.11.020" @default.
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