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• W1972892876 abstract "Optoacoustics provides a unique set of capabilities for bioimaging, associated with the intrinsic combination of ultrasound- and light-related advantages, such as high spatial and temporal resolution as well as powerful spectrally enriched imaging contrast in biological tissues. We demonstrate here, for the first time, the acquisition, processing and visualization of five-dimensional optoacoustic data, thus offering unparallel imaging capacities among the current bioimaging modalities. The newly discovered performance is enabled by simultaneous volumetric detection and processing of multispectral data and is further showcased here by attaining time-resolved volumetric blood oxygenation maps in deep human vessels and real-time tracking of contrast agent distribution in a murine model in vivo. Xosé Luís Deán-Ben and Daniel Razansky at the Technical University of Munich and the Helmholtz Centre Munich have demonstrated three-dimensional multispectral optoacoustic bioimaging in real time. Optoacoustic imaging is a technique wherein a laser beam absorbed by biological tissue induces the creation of a characteristic acoustic signal, which is then detected in the same way as an ultrasound. The technique plays an important role in imaging biological processes in the body due to its excellent optical contrast and high spatial resolution in deep tissues. To detect various substances such as contrast agents in living tissue, scans at multiple wavelengths are required. By employing an ultrafast millisecond timescale laser wavelength tuning along with instantaneous acquisition of volumetric image data, the researchers demonstrated a fully five-dimensional imaging system, thus providing unprecedented flexibility in the mapping of biological processes in-vivo." @default.
• W1972892876 created "2016-06-24" @default.
• W1972892876 creator A5072211195 @default.
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• W1972892876 date "2014-01-31" @default.
• W1972892876 modified "2023-10-18" @default.
• W1972892876 title "Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography" @default.
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• W1972892876 doi "https://doi.org/10.1038/lsa.2014.18" @default.
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