FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972896927> ?p ?o ?g. }

• W1972896927 endingPage "255" @default.
• W1972896927 startingPage "244" @default.
• W1972896927 abstract "Men with erectile dysfunction (ED) are also likely to have associated underlying conditions.This retrospective analysis evaluated the efficacy and safety of vardenafil in men with ED and underlying conditions, including those taking concomitant medications.A total of 13 randomized, double-blind, placebo-controlled clinical studies were included. Vardenafil was administered at a starting dose of 10 mg, adjustable to 5 or 20 mg after 4 weeks. Efficacy analyses were performed on the intent-to-treat (ITT) population, using a last observation carried forward approach. Efficacy was assessed for subgroups of patients with diabetes, hypertension, dyslipidemia, or metabolic syndrome (as defined by International Diabetes Federation criteria). Incidence rates of treatment-emergent adverse events were analyzed overall and by subgroup for patients in the safety population.Primary efficacy measures were the erectile function domain of the International Index of Erectile Function (IIEF-EF), and Sexual Encounter Profile questions 2 and 3 (SEP2, SEP3).In total, 4,326 patients were randomized to treatment; the ITT population included 4,143 patients, with 4,266 patients valid for safety. At 12 weeks, vardenafil therapy was associated with statistically significant improvements from baseline in IIEF-EF scores, and SEP2 and SEP3 success rates, including patients with ED and diabetes, hypertension, dyslipidemia, or metabolic syndrome. These improvements were irrespective of level of glycemic control, or use of concomitant medications for the treatment of diabetes, hypertension, or dyslipidemia. Across all subgroups, the number and type of treatment-emergent adverse events were consistent with results from previous studies of phosphodiesterase type 5 inhibitors in men with ED and underlying conditions.Vardenafil demonstrated favorable efficacy and tolerability in this large pool of patients with ED and underlying conditions. Importantly, the use of concomitant medications was not associated with any noteworthy changes in the efficacy or safety profile of vardenafil." @default.
• W1972896927 created "2016-06-24" @default.
• W1972896927 creator A5003741551 @default.
• W1972896927 creator A5020451632 @default.
• W1972896927 creator A5025657947 @default.
• W1972896927 creator A5036013583 @default.
• W1972896927 creator A5047079599 @default.
• W1972896927 creator A5049759930 @default.
• W1972896927 creator A5087556122 @default.
• W1972896927 date "2010-01-01" @default.
• W1972896927 modified "2023-09-27" @default.
• W1972896927 title "Vardenafil Improves Erectile Function in Men with Erectile Dysfunction and Associated Underlying Conditions, Irrespective of the Use of Concomitant Medications" @default.
• W1972896927 cites W1950745526 @default.
• W1972896927 cites W1956172431 @default.
• W1972896927 cites W1967498394 @default.
• W1972896927 cites W1968613466 @default.
• W1972896927 cites W1975351242 @default.
• W1972896927 cites W1996790738 @default.
• W1972896927 cites W1999059326 @default.
• W1972896927 cites W2001938272 @default.
• W1972896927 cites W2007606095 @default.
• W1972896927 cites W2012294469 @default.
• W1972896927 cites W2012365138 @default.
• W1972896927 cites W2026375486 @default.
• W1972896927 cites W2028224074 @default.
• W1972896927 cites W2033049068 @default.
• W1972896927 cites W2034879310 @default.
• W1972896927 cites W2035776427 @default.
• W1972896927 cites W2038932438 @default.
• W1972896927 cites W2041626476 @default.
• W1972896927 cites W2044955709 @default.
• W1972896927 cites W2059382521 @default.
• W1972896927 cites W2062498555 @default.
• W1972896927 cites W2062907730 @default.
• W1972896927 cites W2063167222 @default.
• W1972896927 cites W2069777370 @default.
• W1972896927 cites W2071103127 @default.
• W1972896927 cites W2072069294 @default.
• W1972896927 cites W2108164252 @default.
• W1972896927 cites W2110388531 @default.
• W1972896927 cites W2120672455 @default.
• W1972896927 cites W2122948438 @default.
• W1972896927 cites W2131071144 @default.
• W1972896927 cites W2131146176 @default.
• W1972896927 cites W2150494864 @default.
• W1972896927 cites W2156867396 @default.
• W1972896927 cites W2157114317 @default.
• W1972896927 cites W2160170325 @default.
• W1972896927 cites W2162077159 @default.
• W1972896927 cites W2297358297 @default.
• W1972896927 cites W4243770305 @default.
• W1972896927 doi "https://doi.org/10.1111/j.1743-6109.2009.01547.x" @default.
• W1972896927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20104672" @default.
• W1972896927 hasPublicationYear "2010" @default.
• W1972896927 type Work @default.
• W1972896927 sameAs 1972896927 @default.
• W1972896927 citedByCount "20" @default.
• W1972896927 countsByYear W19728969272012 @default.
• W1972896927 countsByYear W19728969272013 @default.
• W1972896927 countsByYear W19728969272014 @default.
• W1972896927 countsByYear W19728969272016 @default.
• W1972896927 crossrefType "journal-article" @default.
• W1972896927 hasAuthorship W1972896927A5003741551 @default.
• W1972896927 hasAuthorship W1972896927A5020451632 @default.
• W1972896927 hasAuthorship W1972896927A5025657947 @default.
• W1972896927 hasAuthorship W1972896927A5036013583 @default.
• W1972896927 hasAuthorship W1972896927A5047079599 @default.
• W1972896927 hasAuthorship W1972896927A5049759930 @default.
• W1972896927 hasAuthorship W1972896927A5087556122 @default.
• W1972896927 hasConcept C126322002 @default.
• W1972896927 hasConcept C134018914 @default.
• W1972896927 hasConcept C142724271 @default.
• W1972896927 hasConcept C197934379 @default.
• W1972896927 hasConcept C204787440 @default.
• W1972896927 hasConcept C27081682 @default.
• W1972896927 hasConcept C2777180221 @default.
• W1972896927 hasConcept C2778096610 @default.
• W1972896927 hasConcept C2778822586 @default.
• W1972896927 hasConcept C2779384505 @default.
• W1972896927 hasConcept C2779929075 @default.
• W1972896927 hasConcept C2780473172 @default.
• W1972896927 hasConcept C2780816001 @default.
• W1972896927 hasConcept C2908647359 @default.
• W1972896927 hasConcept C511355011 @default.
• W1972896927 hasConcept C555293320 @default.
• W1972896927 hasConcept C71924100 @default.
• W1972896927 hasConcept C99454951 @default.
• W1972896927 hasConceptScore W1972896927C126322002 @default.
• W1972896927 hasConceptScore W1972896927C134018914 @default.
• W1972896927 hasConceptScore W1972896927C142724271 @default.
• W1972896927 hasConceptScore W1972896927C197934379 @default.
• W1972896927 hasConceptScore W1972896927C204787440 @default.
• W1972896927 hasConceptScore W1972896927C27081682 @default.
• W1972896927 hasConceptScore W1972896927C2777180221 @default.
• W1972896927 hasConceptScore W1972896927C2778096610 @default.
• W1972896927 hasConceptScore W1972896927C2778822586 @default.
• W1972896927 hasConceptScore W1972896927C2779384505 @default.
• W1972896927 hasConceptScore W1972896927C2779929075 @default.

• next