FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1972968981> ?p ?o ?g. }

• W1972968981 endingPage "e6000" @default.
• W1972968981 startingPage "e6000" @default.
• W1972968981 abstract "Background The species Yersinia pestis is commonly divided into three classical biovars, Antiqua, Medievalis, and Orientalis, belonging to subspecies pestis pathogenic for human and the (atypical) non-human pathogenic biovar Microtus (alias Pestoides) including several non-pestis subspecies. Recent progress in molecular typing methods enables large-scale investigations in the population structure of this species. It is now possible to test hypotheses about its evolution which were proposed decades ago. For instance the three classical biovars of different geographical distributions were suggested to originate from Central Asia. Most investigations so far have focused on the typical pestis subspecies representatives found outside of China, whereas the understanding of the emergence of this human pathogen requires the investigation of strains belonging to subspecies pestis from China and to the Microtus biovar. Methodology/Principal Findings Multi-locus VNTR analysis (MLVA) with 25 loci was performed on a collection of Y. pestis isolates originating from the majority of the known foci worldwide and including typical rhamnose-negative subspecies pestis as well as rhamnose-positive subspecies pestis and biovar Microtus. More than 500 isolates from China, the Former Soviet Union (FSU), Mongolia and a number of other foci around the world were characterized and resolved into 350 different genotypes. The data revealed very close relationships existing between some isolates from widely separated foci as well as very high diversity which can conversely be observed between nearby foci. Conclusions/Significance The results obtained are in full agreement with the view that the Y. pestis subsp. pestis pathogenic for humans emerged in the Central Asia region between China, Kazakhstan, Russia and Mongolia, only three clones of which spread out of Central Asia. The relationships among the strains in China, Central Asia and the rest of the world based on the MLVA25 assay provide an unprecedented view on the expansion and microevolution of Y. pestis." @default.
• W1972968981 created "2016-06-24" @default.
• W1972968981 creator A5008817881 @default.
• W1972968981 creator A5013790991 @default.
• W1972968981 creator A5020235101 @default.
• W1972968981 creator A5039933653 @default.
• W1972968981 creator A5043863243 @default.
• W1972968981 creator A5045261152 @default.
• W1972968981 creator A5045824135 @default.
• W1972968981 creator A5047395203 @default.
• W1972968981 creator A5052036404 @default.
• W1972968981 creator A5053825423 @default.
• W1972968981 creator A5055435715 @default.
• W1972968981 creator A5059710815 @default.
• W1972968981 date "2009-06-22" @default.
• W1972968981 modified "2023-10-01" @default.
• W1972968981 title "Genotyping and Phylogenetic Analysis of Yersinia pestis by MLVA: Insights into the Worldwide Expansion of Central Asia Plague Foci" @default.
• W1972968981 cites W116448561 @default.
• W1972968981 cites W143577276 @default.
• W1972968981 cites W1488262302 @default.
• W1972968981 cites W1547524864 @default.
• W1972968981 cites W1571159697 @default.
• W1972968981 cites W1600139443 @default.
• W1972968981 cites W1608909358 @default.
• W1972968981 cites W1666247931 @default.
• W1972968981 cites W1881452270 @default.
• W1972968981 cites W1986171241 @default.
• W1972968981 cites W1995129259 @default.
• W1972968981 cites W2005545569 @default.
• W1972968981 cites W2049490491 @default.
• W1972968981 cites W2061555533 @default.
• W1972968981 cites W2067301040 @default.
• W1972968981 cites W2070747934 @default.
• W1972968981 cites W2074940088 @default.
• W1972968981 cites W2075358898 @default.
• W1972968981 cites W2093869711 @default.
• W1972968981 cites W2099851929 @default.
• W1972968981 cites W2105474110 @default.
• W1972968981 cites W2111205680 @default.
• W1972968981 cites W2133551048 @default.
• W1972968981 cites W2139716519 @default.
• W1972968981 cites W2142080593 @default.
• W1972968981 cites W2143804506 @default.
• W1972968981 cites W2145004751 @default.
• W1972968981 cites W2145912774 @default.
• W1972968981 cites W2150029959 @default.
• W1972968981 cites W2152318137 @default.
• W1972968981 cites W2159138215 @default.
• W1972968981 cites W2168105659 @default.
• W1972968981 cites W2169155895 @default.
• W1972968981 cites W2236896040 @default.
• W1972968981 cites W2325019184 @default.
• W1972968981 cites W2358781322 @default.
• W1972968981 cites W2403930246 @default.
• W1972968981 cites W2407961193 @default.
• W1972968981 cites W2462616347 @default.
• W1972968981 cites W2979981650 @default.
• W1972968981 cites W50958012 @default.
• W1972968981 cites W2415722404 @default.
• W1972968981 doi "https://doi.org/10.1371/journal.pone.0006000" @default.
• W1972968981 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2694983" @default.
• W1972968981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19543392" @default.
• W1972968981 hasPublicationYear "2009" @default.
• W1972968981 type Work @default.
• W1972968981 sameAs 1972968981 @default.
• W1972968981 citedByCount "94" @default.
• W1972968981 countsByYear W19729689812012 @default.
• W1972968981 countsByYear W19729689812013 @default.
• W1972968981 countsByYear W19729689812014 @default.
• W1972968981 countsByYear W19729689812015 @default.
• W1972968981 countsByYear W19729689812016 @default.
• W1972968981 countsByYear W19729689812017 @default.
• W1972968981 countsByYear W19729689812018 @default.
• W1972968981 countsByYear W19729689812019 @default.
• W1972968981 countsByYear W19729689812020 @default.
• W1972968981 countsByYear W19729689812021 @default.
• W1972968981 countsByYear W19729689812022 @default.
• W1972968981 countsByYear W19729689812023 @default.
• W1972968981 crossrefType "journal-article" @default.
• W1972968981 hasAuthorship W1972968981A5008817881 @default.
• W1972968981 hasAuthorship W1972968981A5013790991 @default.
• W1972968981 hasAuthorship W1972968981A5020235101 @default.
• W1972968981 hasAuthorship W1972968981A5039933653 @default.
• W1972968981 hasAuthorship W1972968981A5043863243 @default.
• W1972968981 hasAuthorship W1972968981A5045261152 @default.
• W1972968981 hasAuthorship W1972968981A5045824135 @default.
• W1972968981 hasAuthorship W1972968981A5047395203 @default.
• W1972968981 hasAuthorship W1972968981A5052036404 @default.
• W1972968981 hasAuthorship W1972968981A5053825423 @default.
• W1972968981 hasAuthorship W1972968981A5055435715 @default.
• W1972968981 hasAuthorship W1972968981A5059710815 @default.
• W1972968981 hasBestOaLocation W19729689811 @default.
• W1972968981 hasConcept C104317684 @default.
• W1972968981 hasConcept C105176652 @default.
• W1972968981 hasConcept C135763542 @default.
• W1972968981 hasConcept C141231307 @default.
• W1972968981 hasConcept C159047783 @default.
• W1972968981 hasConcept C166957645 @default.

• next