FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973002883> ?p ?o ?g. }

• W1973002883 endingPage "2196" @default.
• W1973002883 startingPage "2191" @default.
• W1973002883 abstract "In in vitro continuous culture, N (neuroblastic)-, S (substrate adherent)- and I (intermediate)-type cells were identified in human neuroblastoma (NB), where I-type is recognized as a stem cell type. Octamer-binding protein 4 (OCT4) is a cell marker used to identify the stemness of cells, whose roles in regulating I-type NB cells have yet to be fully elucidated. In the present study, we assessed the differentiation regulation role of OCT4 in BE (2)-C of I-type cells. We demonstrated that downregulation of OCT4 expression in BE (2)-C was associated with reduced cell proliferation and loss of colony formation ability on soft agar, and prompted BE (2)-C cells to differentiate to S-type cells. By contrast, overexpression of OCT4 increased cell proliferation and colony formation ratio, but no obvious differentiation promotion was observed. Furthermore, induced differentiation of BE (2)-C cells to S-type by 5-bromo-2'-deoxyuridine (BrdUrd) was accompanied by reduced expression of OCT4." @default.
• W1973002883 created "2016-06-24" @default.
• W1973002883 creator A5032405065 @default.
• W1973002883 creator A5037205945 @default.
• W1973002883 creator A5061789658 @default.
• W1973002883 creator A5081656092 @default.
• W1973002883 date "2013-03-21" @default.
• W1973002883 modified "2023-10-17" @default.
• W1973002883 title "Downregulation of OCT4 promotes differentiation and inhibits growth of BE (2)-C human neuroblastoma I-type cells" @default.
• W1973002883 cites W1521305233 @default.
• W1973002883 cites W1967063990 @default.
• W1973002883 cites W1982580620 @default.
• W1973002883 cites W1985574460 @default.
• W1973002883 cites W1985698425 @default.
• W1973002883 cites W2003520345 @default.
• W1973002883 cites W2013614359 @default.
• W1973002883 cites W2013789580 @default.
• W1973002883 cites W2016766695 @default.
• W1973002883 cites W2021771327 @default.
• W1973002883 cites W2022408616 @default.
• W1973002883 cites W2037174767 @default.
• W1973002883 cites W2039391338 @default.
• W1973002883 cites W2050945292 @default.
• W1973002883 cites W2059038945 @default.
• W1973002883 cites W2065746091 @default.
• W1973002883 cites W2067606868 @default.
• W1973002883 cites W2068416436 @default.
• W1973002883 cites W2071584884 @default.
• W1973002883 cites W2096768863 @default.
• W1973002883 cites W2109726534 @default.
• W1973002883 cites W2115356458 @default.
• W1973002883 cites W2116123637 @default.
• W1973002883 cites W2154500564 @default.
• W1973002883 cites W2162610946 @default.
• W1973002883 cites W4211031423 @default.
• W1973002883 doi "https://doi.org/10.3892/or.2013.2356" @default.
• W1973002883 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23525564" @default.
• W1973002883 hasPublicationYear "2013" @default.
• W1973002883 type Work @default.
• W1973002883 sameAs 1973002883 @default.
• W1973002883 citedByCount "5" @default.
• W1973002883 countsByYear W19730028832014 @default.
• W1973002883 countsByYear W19730028832016 @default.
• W1973002883 countsByYear W19730028832019 @default.
• W1973002883 countsByYear W19730028832020 @default.
• W1973002883 countsByYear W19730028832023 @default.
• W1973002883 crossrefType "journal-article" @default.
• W1973002883 hasAuthorship W1973002883A5032405065 @default.
• W1973002883 hasAuthorship W1973002883A5037205945 @default.
• W1973002883 hasAuthorship W1973002883A5061789658 @default.
• W1973002883 hasAuthorship W1973002883A5081656092 @default.
• W1973002883 hasBestOaLocation W19730028831 @default.
• W1973002883 hasConcept C104317684 @default.
• W1973002883 hasConcept C127561419 @default.
• W1973002883 hasConcept C145103041 @default.
• W1973002883 hasConcept C148738053 @default.
• W1973002883 hasConcept C1491633281 @default.
• W1973002883 hasConcept C153911025 @default.
• W1973002883 hasConcept C189014844 @default.
• W1973002883 hasConcept C20875687 @default.
• W1973002883 hasConcept C26805974 @default.
• W1973002883 hasConcept C2776715637 @default.
• W1973002883 hasConcept C2781018059 @default.
• W1973002883 hasConcept C28328180 @default.
• W1973002883 hasConcept C29537977 @default.
• W1973002883 hasConcept C502942594 @default.
• W1973002883 hasConcept C54355233 @default.
• W1973002883 hasConcept C62112901 @default.
• W1973002883 hasConcept C81885089 @default.
• W1973002883 hasConcept C86803240 @default.
• W1973002883 hasConcept C95444343 @default.
• W1973002883 hasConceptScore W1973002883C104317684 @default.
• W1973002883 hasConceptScore W1973002883C127561419 @default.
• W1973002883 hasConceptScore W1973002883C145103041 @default.
• W1973002883 hasConceptScore W1973002883C148738053 @default.
• W1973002883 hasConceptScore W1973002883C1491633281 @default.
• W1973002883 hasConceptScore W1973002883C153911025 @default.
• W1973002883 hasConceptScore W1973002883C189014844 @default.
• W1973002883 hasConceptScore W1973002883C20875687 @default.
• W1973002883 hasConceptScore W1973002883C26805974 @default.
• W1973002883 hasConceptScore W1973002883C2776715637 @default.
• W1973002883 hasConceptScore W1973002883C2781018059 @default.
• W1973002883 hasConceptScore W1973002883C28328180 @default.
• W1973002883 hasConceptScore W1973002883C29537977 @default.
• W1973002883 hasConceptScore W1973002883C502942594 @default.
• W1973002883 hasConceptScore W1973002883C54355233 @default.
• W1973002883 hasConceptScore W1973002883C62112901 @default.
• W1973002883 hasConceptScore W1973002883C81885089 @default.
• W1973002883 hasConceptScore W1973002883C86803240 @default.
• W1973002883 hasConceptScore W1973002883C95444343 @default.
• W1973002883 hasIssue "6" @default.
• W1973002883 hasLocation W19730028831 @default.
• W1973002883 hasLocation W19730028832 @default.
• W1973002883 hasOpenAccess W1973002883 @default.
• W1973002883 hasPrimaryLocation W19730028831 @default.
• W1973002883 hasRelatedWork W2023126270 @default.
• W1973002883 hasRelatedWork W2064378035 @default.
• W1973002883 hasRelatedWork W2150002449 @default.

• next