Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973021615> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1973021615 endingPage "21" @default.
- W1973021615 startingPage "17" @default.
- W1973021615 abstract "Background: Cutaneous leishmaniasis (CL) caused by Leishmania major is common in Middle East countries. Most therapies are limited and there is no effective vaccine for leishmaniasis. It has been reported that the ancient practice of wet cupping has been effective in treatment of drug resistant CL in humans. The purpose of this present study was to evaluate the efficacy of wet-cupping in treatment of L. major infected BALB/C mice.
 Methods: We designed a randomized clinical trial using 12 male BALB/c mice, aged 8-10 weeks (six mice for each experimental and control group). Each mouse was infected with L. major on the left hind footpad. Mice in the experimental group underwent wet-cupping once a week, up to 6 weeks. The appearance of local reaction in the parasite inoculated paw was monitored and footpad thickness was measured for 7 weeks in both groups. Then all mice were killed and their spleen and lymph node cells were cultured and the level of IFN- γ and IL-4 of cultured cells supernatant were measured as the markers of TH1 and TH2, respectively.
 Results: Lesion size thickness in the intervention mice seemed to grow faster than control ones. There were no significant differences in animal weight, spleen and lymph node weight and total cell number. The level of INF-γ and IL-4 produced by spleen cells of intervention mice was not significantly different from control mice (p=NS).
 Conclusion: Our study showed that wet-cupping has no significant treatment effect on coetaneous leishmaniasis in BALB/c mice. Interestingly, the disease was more severe in the intervention group." @default.
- W1973021615 created "2016-06-24" @default.
- W1973021615 creator A5022528166 @default.
- W1973021615 creator A5022776797 @default.
- W1973021615 creator A5025165896 @default.
- W1973021615 creator A5040985719 @default.
- W1973021615 date "2015-03-07" @default.
- W1973021615 modified "2023-09-26" @default.
- W1973021615 title "EFFECTIVENESS OF WET-CUPPING IN TREATMENT OF BALB/C MICE INFECTED BY LEISHMANIA MAJOR; PILOT RANDOMIZED TRIAL" @default.
- W1973021615 cites W1977671739 @default.
- W1973021615 cites W1984952081 @default.
- W1973021615 cites W2011083855 @default.
- W1973021615 cites W2020941408 @default.
- W1973021615 cites W2034687214 @default.
- W1973021615 cites W2044334988 @default.
- W1973021615 cites W2057828074 @default.
- W1973021615 cites W2067609315 @default.
- W1973021615 cites W2096156614 @default.
- W1973021615 cites W2100203705 @default.
- W1973021615 cites W2161208324 @default.
- W1973021615 cites W2164932549 @default.
- W1973021615 cites W2340271011 @default.
- W1973021615 doi "https://doi.org/10.21010/ajtcam.v12i2.4" @default.
- W1973021615 hasPublicationYear "2015" @default.
- W1973021615 type Work @default.
- W1973021615 sameAs 1973021615 @default.
- W1973021615 citedByCount "0" @default.
- W1973021615 crossrefType "journal-article" @default.
- W1973021615 hasAuthorship W1973021615A5022528166 @default.
- W1973021615 hasAuthorship W1973021615A5022776797 @default.
- W1973021615 hasAuthorship W1973021615A5025165896 @default.
- W1973021615 hasAuthorship W1973021615A5040985719 @default.
- W1973021615 hasBestOaLocation W19730216151 @default.
- W1973021615 hasConcept C126322002 @default.
- W1973021615 hasConcept C136764020 @default.
- W1973021615 hasConcept C142724271 @default.
- W1973021615 hasConcept C168563851 @default.
- W1973021615 hasConcept C203014093 @default.
- W1973021615 hasConcept C2776390293 @default.
- W1973021615 hasConcept C2776529007 @default.
- W1973021615 hasConcept C2776555147 @default.
- W1973021615 hasConcept C2778702967 @default.
- W1973021615 hasConcept C2779720271 @default.
- W1973021615 hasConcept C2780599195 @default.
- W1973021615 hasConcept C2780849966 @default.
- W1973021615 hasConcept C2780931953 @default.
- W1973021615 hasConcept C2781092759 @default.
- W1973021615 hasConcept C2781156865 @default.
- W1973021615 hasConcept C41008148 @default.
- W1973021615 hasConcept C71924100 @default.
- W1973021615 hasConcept C71928629 @default.
- W1973021615 hasConcept C8891405 @default.
- W1973021615 hasConcept C98274493 @default.
- W1973021615 hasConceptScore W1973021615C126322002 @default.
- W1973021615 hasConceptScore W1973021615C136764020 @default.
- W1973021615 hasConceptScore W1973021615C142724271 @default.
- W1973021615 hasConceptScore W1973021615C168563851 @default.
- W1973021615 hasConceptScore W1973021615C203014093 @default.
- W1973021615 hasConceptScore W1973021615C2776390293 @default.
- W1973021615 hasConceptScore W1973021615C2776529007 @default.
- W1973021615 hasConceptScore W1973021615C2776555147 @default.
- W1973021615 hasConceptScore W1973021615C2778702967 @default.
- W1973021615 hasConceptScore W1973021615C2779720271 @default.
- W1973021615 hasConceptScore W1973021615C2780599195 @default.
- W1973021615 hasConceptScore W1973021615C2780849966 @default.
- W1973021615 hasConceptScore W1973021615C2780931953 @default.
- W1973021615 hasConceptScore W1973021615C2781092759 @default.
- W1973021615 hasConceptScore W1973021615C2781156865 @default.
- W1973021615 hasConceptScore W1973021615C41008148 @default.
- W1973021615 hasConceptScore W1973021615C71924100 @default.
- W1973021615 hasConceptScore W1973021615C71928629 @default.
- W1973021615 hasConceptScore W1973021615C8891405 @default.
- W1973021615 hasConceptScore W1973021615C98274493 @default.
- W1973021615 hasIssue "2" @default.
- W1973021615 hasLocation W19730216151 @default.
- W1973021615 hasLocation W19730216152 @default.
- W1973021615 hasOpenAccess W1973021615 @default.
- W1973021615 hasPrimaryLocation W19730216151 @default.
- W1973021615 hasRelatedWork W1973021615 @default.
- W1973021615 hasRelatedWork W1989938173 @default.
- W1973021615 hasRelatedWork W1997570781 @default.
- W1973021615 hasRelatedWork W2065608771 @default.
- W1973021615 hasRelatedWork W2175371704 @default.
- W1973021615 hasRelatedWork W2233281294 @default.
- W1973021615 hasRelatedWork W2398585436 @default.
- W1973021615 hasRelatedWork W3042515694 @default.
- W1973021615 hasRelatedWork W3105524026 @default.
- W1973021615 hasRelatedWork W4247804645 @default.
- W1973021615 hasVolume "12" @default.
- W1973021615 isParatext "false" @default.
- W1973021615 isRetracted "false" @default.
- W1973021615 magId "1973021615" @default.
- W1973021615 workType "article" @default.