FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973050078> ?p ?o ?g. }

• W1973050078 abstract "This paper reports how poly(DL-lactide) microspheres of different molecular weight and BSA content were manufactured in order to evaluate the influence of these two variables on the protein release profile, using a composite central rotational design. The microspheres were prepared by a double emulsion method using different w/o phase ratios. The BSA encapsulated was about 80% of the theoretical amount incorporated. The resulting microspheres proved porous except for three batches. The release of BSA from microspheres presented two phases, first a high burst effect ranging from 37.3 to 75% of the protein incorporated, and a second slower one. Analysis of the release results clearly shows a positive linear dependence of the slope of the slow release phase on the molecular weight of polymer, due most likely to the formation of hydrogen bridges between the terminal -OH groups of the polymer chains and the solitary pairs of donor atoms of the protein. Non-porous microspheres with a lesser burst effect were obtained by decreasing the w/o ratio of the first emulsion during the preparation process." @default.
• W1973050078 created "2016-06-24" @default.
• W1973050078 creator A5028088132 @default.
• W1973050078 creator A5069394447 @default.
• W1973050078 creator A5082796947 @default.
• W1973050078 date "1995-10-01" @default.
• W1973050078 modified "2023-09-27" @default.
• W1973050078 title "Release control of albumin from polylactic acid microspheres" @default.
• W1973050078 cites W1536081943 @default.
• W1973050078 cites W1539664785 @default.
• W1973050078 cites W1775749144 @default.
• W1973050078 cites W1974933001 @default.
• W1973050078 cites W1996017656 @default.
• W1973050078 cites W2012859673 @default.
• W1973050078 cites W2021817350 @default.
• W1973050078 cites W2024095018 @default.
• W1973050078 cites W2026161005 @default.
• W1973050078 cites W2032929189 @default.
• W1973050078 cites W2060344491 @default.
• W1973050078 cites W2077042278 @default.
• W1973050078 cites W2083717249 @default.
• W1973050078 cites W2090584491 @default.
• W1973050078 cites W2095536362 @default.
• W1973050078 cites W2124054973 @default.
• W1973050078 cites W23296051 @default.
• W1973050078 cites W2332342931 @default.
• W1973050078 cites W2333670789 @default.
• W1973050078 cites W4247125469 @default.
• W1973050078 doi "https://doi.org/10.1016/0378-5173(95)00128-6" @default.
• W1973050078 hasPublicationYear "1995" @default.
• W1973050078 type Work @default.
• W1973050078 sameAs 1973050078 @default.
• W1973050078 citedByCount "22" @default.
• W1973050078 countsByYear W19730500782014 @default.
• W1973050078 countsByYear W19730500782015 @default.
• W1973050078 countsByYear W19730500782017 @default.
• W1973050078 crossrefType "journal-article" @default.
• W1973050078 hasAuthorship W1973050078A5028088132 @default.
• W1973050078 hasAuthorship W1973050078A5069394447 @default.
• W1973050078 hasAuthorship W1973050078A5082796947 @default.
• W1973050078 hasConcept C104779481 @default.
• W1973050078 hasConcept C127413603 @default.
• W1973050078 hasConcept C159985019 @default.
• W1973050078 hasConcept C163588942 @default.
• W1973050078 hasConcept C171250308 @default.
• W1973050078 hasConcept C178790620 @default.
• W1973050078 hasConcept C185592680 @default.
• W1973050078 hasConcept C188027245 @default.
• W1973050078 hasConcept C189942447 @default.
• W1973050078 hasConcept C192562407 @default.
• W1973050078 hasConcept C2778123984 @default.
• W1973050078 hasConcept C2781162966 @default.
• W1973050078 hasConcept C42360764 @default.
• W1973050078 hasConcept C43617362 @default.
• W1973050078 hasConcept C44280652 @default.
• W1973050078 hasConcept C521977710 @default.
• W1973050078 hasConcept C6648577 @default.
• W1973050078 hasConcept C86807702 @default.
• W1973050078 hasConceptScore W1973050078C104779481 @default.
• W1973050078 hasConceptScore W1973050078C127413603 @default.
• W1973050078 hasConceptScore W1973050078C159985019 @default.
• W1973050078 hasConceptScore W1973050078C163588942 @default.
• W1973050078 hasConceptScore W1973050078C171250308 @default.
• W1973050078 hasConceptScore W1973050078C178790620 @default.
• W1973050078 hasConceptScore W1973050078C185592680 @default.
• W1973050078 hasConceptScore W1973050078C188027245 @default.
• W1973050078 hasConceptScore W1973050078C189942447 @default.
• W1973050078 hasConceptScore W1973050078C192562407 @default.
• W1973050078 hasConceptScore W1973050078C2778123984 @default.
• W1973050078 hasConceptScore W1973050078C2781162966 @default.
• W1973050078 hasConceptScore W1973050078C42360764 @default.
• W1973050078 hasConceptScore W1973050078C43617362 @default.
• W1973050078 hasConceptScore W1973050078C44280652 @default.
• W1973050078 hasConceptScore W1973050078C521977710 @default.
• W1973050078 hasConceptScore W1973050078C6648577 @default.
• W1973050078 hasConceptScore W1973050078C86807702 @default.
• W1973050078 hasLocation W19730500781 @default.
• W1973050078 hasOpenAccess W1973050078 @default.
• W1973050078 hasPrimaryLocation W19730500781 @default.
• W1973050078 hasRelatedWork W161683572 @default.
• W1973050078 hasRelatedWork W179984412 @default.
• W1973050078 hasRelatedWork W1963790829 @default.
• W1973050078 hasRelatedWork W2001761296 @default.
• W1973050078 hasRelatedWork W2010581603 @default.
• W1973050078 hasRelatedWork W2024978300 @default.
• W1973050078 hasRelatedWork W2030579793 @default.
• W1973050078 hasRelatedWork W2039008589 @default.
• W1973050078 hasRelatedWork W2042026725 @default.
• W1973050078 hasRelatedWork W2065677764 @default.
• W1973050078 hasRelatedWork W2070134013 @default.
• W1973050078 hasRelatedWork W2093740518 @default.
• W1973050078 hasRelatedWork W2096088598 @default.
• W1973050078 hasRelatedWork W2096448992 @default.
• W1973050078 hasRelatedWork W2096890437 @default.
• W1973050078 hasRelatedWork W2105532128 @default.
• W1973050078 hasRelatedWork W2137002232 @default.
• W1973050078 hasRelatedWork W2154869591 @default.
• W1973050078 hasRelatedWork W2164241087 @default.
• W1973050078 hasRelatedWork W2142680236 @default.
• W1973050078 isParatext "false" @default.

• next