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• W1973063670 abstract "13C[(15)N] and (13)C[(19)F] rotational-echo double-resonance NMR have been used to characterize the enzyme-bound structure of ZK-816042, an amidine-imidazoline inhibitor of human factor Xa (FXa). The NMR experiments were performed on a lyophilized FXa-inhibitor complex. The complex was formed in solution in the presence of stabilizing excipients and frozen after gradual supercooling prior to lyophilization. The results indicate that the inhibitor binds with a distribution of orientations of the imidazoline ring." @default.
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• W1973063670 date "2003-06-17" @default.
• W1973063670 modified "2023-10-18" @default.
• W1973063670 title "Conformation of a Bound Inhibitor of Blood Coagulant Factor Xa" @default.
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• W1973063670 doi "https://doi.org/10.1021/bi027369g" @default.
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