FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973119983> ?p ?o ?g. }

• W1973119983 endingPage "30" @default.
• W1973119983 startingPage "24" @default.
• W1973119983 abstract "Background Changes in the hypothalamic–pituitary–adrenal (HPA) axis, as evidenced by patterns of cortisol secretion, have been of interest in understanding depression and anxiety disorders across the life span. Previous studies of pediatric depression have pointed to the period around sleep onset as a key time point for observing alterations in cortisol secretion associated with affective disorders. Evidence also indicates that pubertal development may influence the expression of HPA dysregulation. We hypothesized that adolescents with depression and youth with anxiety disorders exhibit elevated peri-sleep-onset cortisol. Methods Plasma cortisol was sampled every 20 min around sleep onset from children and adolescents with major depressive disorder (n = 116), anxiety disorders (n = 32), or no history of psychiatric disorder (control; n = 76). Sleep onset was determined by polysomnography. Classification of participants as children or adolescents was based on Tanner staging of pubertal maturation. Results Children with anxiety disorders had higher peri-sleep-onset cortisol than children with depression or control children. Adolescents with depression had marginally higher peri-sleep-onset cortisol than control adolescents and significantly higher peri-sleep-onset cortisol than children with depression. Conclusions Depression and anxiety are associated with altered cortisol secretion around sleep onset, and these changes appear to be influenced by pubertal maturation. Changes in the hypothalamic–pituitary–adrenal (HPA) axis, as evidenced by patterns of cortisol secretion, have been of interest in understanding depression and anxiety disorders across the life span. Previous studies of pediatric depression have pointed to the period around sleep onset as a key time point for observing alterations in cortisol secretion associated with affective disorders. Evidence also indicates that pubertal development may influence the expression of HPA dysregulation. We hypothesized that adolescents with depression and youth with anxiety disorders exhibit elevated peri-sleep-onset cortisol. Plasma cortisol was sampled every 20 min around sleep onset from children and adolescents with major depressive disorder (n = 116), anxiety disorders (n = 32), or no history of psychiatric disorder (control; n = 76). Sleep onset was determined by polysomnography. Classification of participants as children or adolescents was based on Tanner staging of pubertal maturation. Children with anxiety disorders had higher peri-sleep-onset cortisol than children with depression or control children. Adolescents with depression had marginally higher peri-sleep-onset cortisol than control adolescents and significantly higher peri-sleep-onset cortisol than children with depression. Depression and anxiety are associated with altered cortisol secretion around sleep onset, and these changes appear to be influenced by pubertal maturation." @default.
• W1973119983 created "2016-06-24" @default.
• W1973119983 creator A5014163066 @default.
• W1973119983 creator A5021097660 @default.
• W1973119983 creator A5025117351 @default.
• W1973119983 creator A5040996077 @default.
• W1973119983 creator A5051015778 @default.
• W1973119983 creator A5061001915 @default.
• W1973119983 date "2006-01-01" @default.
• W1973119983 modified "2023-09-25" @default.
• W1973119983 title "Peri-Sleep-Onset Cortisol Levels in Children and Adolescents with Affective Disorders" @default.
• W1973119983 cites W1215075678 @default.
• W1973119983 cites W1628939789 @default.
• W1973119983 cites W1964249784 @default.
• W1973119983 cites W1965376635 @default.
• W1973119983 cites W1968476011 @default.
• W1973119983 cites W1969288273 @default.
• W1973119983 cites W1973658723 @default.
• W1973119983 cites W1974150133 @default.
• W1973119983 cites W1974800864 @default.
• W1973119983 cites W1983302342 @default.
• W1973119983 cites W1985168358 @default.
• W1973119983 cites W1991353592 @default.
• W1973119983 cites W2006770638 @default.
• W1973119983 cites W2009876831 @default.
• W1973119983 cites W2011943672 @default.
• W1973119983 cites W2017538352 @default.
• W1973119983 cites W2021634787 @default.
• W1973119983 cites W2023777866 @default.
• W1973119983 cites W2036396063 @default.
• W1973119983 cites W2047909845 @default.
• W1973119983 cites W2049863677 @default.
• W1973119983 cites W2053007325 @default.
• W1973119983 cites W2056722085 @default.
• W1973119983 cites W2060491921 @default.
• W1973119983 cites W2068788935 @default.
• W1973119983 cites W2069083186 @default.
• W1973119983 cites W2071376560 @default.
• W1973119983 cites W2077572353 @default.
• W1973119983 cites W2078124330 @default.
• W1973119983 cites W2085839022 @default.
• W1973119983 cites W2093278865 @default.
• W1973119983 cites W2093773635 @default.
• W1973119983 cites W2099303532 @default.
• W1973119983 cites W2105194498 @default.
• W1973119983 cites W2114613490 @default.
• W1973119983 cites W2117309811 @default.
• W1973119983 cites W2118812941 @default.
• W1973119983 cites W2138632275 @default.
• W1973119983 cites W2141124547 @default.
• W1973119983 cites W2144859742 @default.
• W1973119983 cites W2179791495 @default.
• W1973119983 cites W2395625506 @default.
• W1973119983 cites W2402027586 @default.
• W1973119983 doi "https://doi.org/10.1016/j.biopsych.2005.06.002" @default.
• W1973119983 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2692857" @default.
• W1973119983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16112658" @default.
• W1973119983 hasPublicationYear "2006" @default.
• W1973119983 type Work @default.
• W1973119983 sameAs 1973119983 @default.
• W1973119983 citedByCount "111" @default.
• W1973119983 countsByYear W19731199832012 @default.
• W1973119983 countsByYear W19731199832013 @default.
• W1973119983 countsByYear W19731199832014 @default.
• W1973119983 countsByYear W19731199832015 @default.
• W1973119983 countsByYear W19731199832016 @default.
• W1973119983 countsByYear W19731199832017 @default.
• W1973119983 countsByYear W19731199832018 @default.
• W1973119983 countsByYear W19731199832019 @default.
• W1973119983 countsByYear W19731199832020 @default.
• W1973119983 countsByYear W19731199832021 @default.
• W1973119983 countsByYear W19731199832023 @default.
• W1973119983 crossrefType "journal-article" @default.
• W1973119983 hasAuthorship W1973119983A5014163066 @default.
• W1973119983 hasAuthorship W1973119983A5021097660 @default.
• W1973119983 hasAuthorship W1973119983A5025117351 @default.
• W1973119983 hasAuthorship W1973119983A5040996077 @default.
• W1973119983 hasAuthorship W1973119983A5051015778 @default.
• W1973119983 hasAuthorship W1973119983A5061001915 @default.
• W1973119983 hasBestOaLocation W19731199832 @default.
• W1973119983 hasConcept C111919701 @default.
• W1973119983 hasConcept C118552586 @default.
• W1973119983 hasConcept C126322002 @default.
• W1973119983 hasConcept C134018914 @default.
• W1973119983 hasConcept C139719470 @default.
• W1973119983 hasConcept C1513209611 @default.
• W1973119983 hasConcept C15744967 @default.
• W1973119983 hasConcept C162324750 @default.
• W1973119983 hasConcept C2775841894 @default.
• W1973119983 hasConcept C2776867660 @default.
• W1973119983 hasConcept C2778205975 @default.
• W1973119983 hasConcept C2778709874 @default.
• W1973119983 hasConcept C2779146795 @default.
• W1973119983 hasConcept C2781210498 @default.
• W1973119983 hasConcept C2781326671 @default.
• W1973119983 hasConcept C41008148 @default.
• W1973119983 hasConcept C558461103 @default.
• W1973119983 hasConcept C71315377 @default.

• next