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- W1973150545 abstract "Effort thrombosis of the axillary-subclavian vein (Paget-Schroetter syndrome) develops usually secondary to heavy arm exertion. An underlying chronic venous compressive anomaly at the thoracic outlet or intimal damage of the axillary vein following forceful hyperabduction, external rotation of the shoulder joint has been proposed to explain the pathophysiology of this thrombosis. This condition is usually not attributed to an underlying hypercoagulability such as deficiency of natural coagulation inhibitors. Here, the authors present a case with thrombosis of the axillary-subclavian vein following an effort, with factor V Leiden and prothrombin 20210A mutations. Both factor V Leiden and the genetic variant in the prothrombin gene have been shown to confer an increased risk for venous thrombosis. Although rare, effort thrombosis may develop in a patient with hereditary thrombophilia, so laboratory evaluation should include the common causes of thrombosis." @default.
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- W1973150545 date "1999-08-01" @default.
- W1973150545 modified "2023-10-16" @default.
- W1973150545 title "Paget-Schroetter Syndrome Associated with FV:Q506 and Prothrombin 20210A" @default.
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- W1973150545 doi "https://doi.org/10.1177/000331979905000811" @default.
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