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- W1973163544 abstract "A fraction of the α-globulins (NHG) from normal human serum was cytotoxic for mouse L-cells in culture and Meth A tumors in mice. NHG inhibited the growth in vitro of human colon cancer (HT-29), melanoma (RPMI 7931) and a neuroblastoma cell line. Survival of HeLa S-3 cell colonies after 24 h exposure to 25, 50, 75 or 100 μg NHG/ml medium was 86%, 77%, 40% and 10%, respectively. Whole human serum or purified serum albumin had no anti-HeLa cell activity. These results confirm the presence of a protein in human serum with antitumor activity. An assay for NHG using HeLa S-3 tumor cells is described." @default.
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- W1973163544 date "1981-02-01" @default.
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- W1973163544 title "A protein fraction (NHG) from serum of normal humans which is cytotoxic for HeLa cells in culture" @default.
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- W1973163544 doi "https://doi.org/10.1016/0304-3835(81)90101-4" @default.
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