FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973190063> ?p ?o ?g. }

• W1973190063 endingPage "e41325" @default.
• W1973190063 startingPage "e41325" @default.
• W1973190063 abstract "Background Intravitreal anti-vascular endothelial growth factor (VEGF) monoclonal antibodies are used in ocular neovascular diseases. A consensus has emerged that intravenous anti-VEGF can increase the risk of arterial thromboembolic events. However, the role of intravitreal anti-VEGF in arterial thromboembolism is controversial. Therefore, we did a systematic review and meta-analysis to investigate the effects of intravitreal anti-VEGF on the risk of arterial thromboembolic events. Methods Electronic databases were searched to identify relevant randomized clinical trials comparing intravitreal anti-VEGF with controls. Criteria for inclusion in our meta-analysis included a study duration of no less than 12 months, the use of a randomized control group not receiving any intravitreal active agent, and the availability of outcome data for arterial thromboembolic events, myocardial infarction, cerebrovascular accidents, and vascular death. The risk ratios and 95% CIs were calculated using a fixed-effects or random-effects model, depending on the heterogeneity of the included studies. Results A total of 4942 patients with a variety of ocular neovascular diseases from 13 randomized controlled trials were identified and included for analysis. There was no significant difference between intravitreal anti-VEGF and control in the risk of all events, with risk ratios of 0.87 (95% CI, 0.64 to 1.19) for arterial thromboembolic events, 0.96 (95% CI, 0.55–1.68) for cerebrovascular accidents, 0.69 (95% CI 0.40–1.21) for myocardial infarctions, and 0.68 (95% CI, 0.37–1.27) for vascular death. Conclusions The strength evidence suggests that the intravitreal use of anti-VEGF antibodies is not associated with an increased risk of arterial thromboembolic events." @default.
• W1973190063 created "2016-06-24" @default.
• W1973190063 creator A5018256186 @default.
• W1973190063 creator A5044366915 @default.
• W1973190063 creator A5044377881 @default.
• W1973190063 creator A5081180912 @default.
• W1973190063 date "2012-07-19" @default.
• W1973190063 modified "2023-10-16" @default.
• W1973190063 title "Effect of Intravitreal Anti-Vascular Endothelial Growth Factor Therapy on the Risk of Arterial Thromboembolic Events: A Meta-Analysis" @default.
• W1973190063 cites W1982179488 @default.
• W1973190063 cites W1982228885 @default.
• W1973190063 cites W1986215651 @default.
• W1973190063 cites W2000000541 @default.
• W1973190063 cites W2012906786 @default.
• W1973190063 cites W2030593253 @default.
• W1973190063 cites W2036279685 @default.
• W1973190063 cites W2052204551 @default.
• W1973190063 cites W2068742492 @default.
• W1973190063 cites W2071074251 @default.
• W1973190063 cites W2081680826 @default.
• W1973190063 cites W2085174145 @default.
• W1973190063 cites W2095251825 @default.
• W1973190063 cites W2096134439 @default.
• W1973190063 cites W2107328434 @default.
• W1973190063 cites W2117696490 @default.
• W1973190063 cites W2121785313 @default.
• W1973190063 cites W2124415048 @default.
• W1973190063 cites W2125435699 @default.
• W1973190063 cites W2126930838 @default.
• W1973190063 cites W2127125241 @default.
• W1973190063 cites W2130245376 @default.
• W1973190063 cites W2145835533 @default.
• W1973190063 cites W2153461920 @default.
• W1973190063 cites W2157027608 @default.
• W1973190063 cites W2157769714 @default.
• W1973190063 cites W2157823046 @default.
• W1973190063 cites W2159841299 @default.
• W1973190063 cites W2160745745 @default.
• W1973190063 cites W2161279821 @default.
• W1973190063 cites W2161588304 @default.
• W1973190063 cites W2164855431 @default.
• W1973190063 cites W2166573361 @default.
• W1973190063 cites W22697100 @default.
• W1973190063 cites W4237391818 @default.
• W1973190063 cites W4239471829 @default.
• W1973190063 doi "https://doi.org/10.1371/journal.pone.0041325" @default.
• W1973190063 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3400599" @default.
• W1973190063 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22829940" @default.
• W1973190063 hasPublicationYear "2012" @default.
• W1973190063 type Work @default.
• W1973190063 sameAs 1973190063 @default.
• W1973190063 citedByCount "11" @default.
• W1973190063 countsByYear W19731900632013 @default.
• W1973190063 countsByYear W19731900632014 @default.
• W1973190063 countsByYear W19731900632015 @default.
• W1973190063 countsByYear W19731900632016 @default.
• W1973190063 countsByYear W19731900632018 @default.
• W1973190063 countsByYear W19731900632019 @default.
• W1973190063 countsByYear W19731900632020 @default.
• W1973190063 countsByYear W19731900632023 @default.
• W1973190063 crossrefType "journal-article" @default.
• W1973190063 hasAuthorship W1973190063A5018256186 @default.
• W1973190063 hasAuthorship W1973190063A5044366915 @default.
• W1973190063 hasAuthorship W1973190063A5044377881 @default.
• W1973190063 hasAuthorship W1973190063A5081180912 @default.
• W1973190063 hasBestOaLocation W19731900631 @default.
• W1973190063 hasConcept C126322002 @default.
• W1973190063 hasConcept C164705383 @default.
• W1973190063 hasConcept C168563851 @default.
• W1973190063 hasConcept C500558357 @default.
• W1973190063 hasConcept C50440223 @default.
• W1973190063 hasConcept C71924100 @default.
• W1973190063 hasConcept C95190672 @default.
• W1973190063 hasConceptScore W1973190063C126322002 @default.
• W1973190063 hasConceptScore W1973190063C164705383 @default.
• W1973190063 hasConceptScore W1973190063C168563851 @default.
• W1973190063 hasConceptScore W1973190063C500558357 @default.
• W1973190063 hasConceptScore W1973190063C50440223 @default.
• W1973190063 hasConceptScore W1973190063C71924100 @default.
• W1973190063 hasConceptScore W1973190063C95190672 @default.
• W1973190063 hasIssue "7" @default.
• W1973190063 hasLocation W19731900631 @default.
• W1973190063 hasLocation W19731900632 @default.
• W1973190063 hasLocation W19731900633 @default.
• W1973190063 hasLocation W19731900634 @default.
• W1973190063 hasLocation W19731900635 @default.
• W1973190063 hasLocation W19731900636 @default.
• W1973190063 hasOpenAccess W1973190063 @default.
• W1973190063 hasPrimaryLocation W19731900631 @default.
• W1973190063 hasRelatedWork W1531601525 @default.
• W1973190063 hasRelatedWork W2032406302 @default.
• W1973190063 hasRelatedWork W2167330595 @default.
• W1973190063 hasRelatedWork W2758277628 @default.
• W1973190063 hasRelatedWork W2948807893 @default.
• W1973190063 hasRelatedWork W3173606202 @default.
• W1973190063 hasRelatedWork W3183948672 @default.
• W1973190063 hasRelatedWork W4387497383 @default.
• W1973190063 hasRelatedWork W2778153218 @default.

• next