FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973196144> ?p ?o ?g. }

• W1973196144 endingPage "2675" @default.
• W1973196144 startingPage "2667" @default.
• W1973196144 abstract "Carr−Purcell−Meiboom−Gill relaxation dispersion NMR spectroscopy has evolved into a powerful approach for the study of low populated, invisible conformations of biological molecules. One of the powerful features of the experiment is that chemical shift differences between the exchanging conformers can be obtained, providing structural information about invisible excited states. Through the development of new labeling approaches and NMR experiments it is now possible to measure backbone 13Cα and 13CO relaxation dispersion profiles in proteins without complications from 13C−13C couplings. Such measurements are presented here, along with those that probe exchange using 15N and 1HN nuclei. A key experimental design has been the choice of an exchanging system where excited-state chemical shifts were known from independent measurement. Thus it is possible to evaluate quantitatively the accuracy of chemical shift differences obtained in dispersion experiments and to establish that in general very accurate values can be obtained. The experimental work is supplemented by computations that suggest that similarly accurate shifts can be measured in many cases for systems with exchange rates and populations that fall within the range of those that can be quantified by relaxation dispersion. The accuracy of the extracted chemical shifts opens up the possibility of obtaining quantitative structural information of invisible states of the sort that is now available from chemical shifts recorded on ground states of proteins." @default.
• W1973196144 created "2016-06-24" @default.
• W1973196144 creator A5003139041 @default.
• W1973196144 creator A5007320208 @default.
• W1973196144 creator A5018102939 @default.
• W1973196144 creator A5020050875 @default.
• W1973196144 creator A5067229912 @default.
• W1973196144 date "2008-02-01" @default.
• W1973196144 modified "2023-10-15" @default.
• W1973196144 title "Probing Chemical Shifts of Invisible States of Proteins with Relaxation Dispersion NMR Spectroscopy: How Well Can We Do?" @default.
• W1973196144 cites W1016793671 @default.
• W1973196144 cites W1486795616 @default.
• W1973196144 cites W1487346929 @default.
• W1973196144 cites W1586504007 @default.
• W1973196144 cites W1589295940 @default.
• W1973196144 cites W1969103850 @default.
• W1973196144 cites W1976270316 @default.
• W1973196144 cites W1977179882 @default.
• W1973196144 cites W1978017493 @default.
• W1973196144 cites W1978545297 @default.
• W1973196144 cites W1981159786 @default.
• W1973196144 cites W1985767604 @default.
• W1973196144 cites W1987528091 @default.
• W1973196144 cites W1994939140 @default.
• W1973196144 cites W2000513450 @default.
• W1973196144 cites W2003119577 @default.
• W1973196144 cites W2007095495 @default.
• W1973196144 cites W2007832693 @default.
• W1973196144 cites W2009337785 @default.
• W1973196144 cites W2013593586 @default.
• W1973196144 cites W2026042792 @default.
• W1973196144 cites W2031292508 @default.
• W1973196144 cites W2033762168 @default.
• W1973196144 cites W2036190761 @default.
• W1973196144 cites W2039543246 @default.
• W1973196144 cites W2046002103 @default.
• W1973196144 cites W2051177628 @default.
• W1973196144 cites W2055497972 @default.
• W1973196144 cites W2066961392 @default.
• W1973196144 cites W2076283593 @default.
• W1973196144 cites W2083144176 @default.
• W1973196144 cites W2095400080 @default.
• W1973196144 cites W2117387890 @default.
• W1973196144 cites W2148521301 @default.
• W1973196144 cites W2148939731 @default.
• W1973196144 cites W2165849976 @default.
• W1973196144 cites W2169821755 @default.
• W1973196144 cites W2318867253 @default.
• W1973196144 cites W240415867 @default.
• W1973196144 cites W4242009576 @default.
• W1973196144 cites W49665239 @default.
• W1973196144 cites W93844258 @default.
• W1973196144 doi "https://doi.org/10.1021/ja078337p" @default.
• W1973196144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18237174" @default.
• W1973196144 hasPublicationYear "2008" @default.
• W1973196144 type Work @default.
• W1973196144 sameAs 1973196144 @default.
• W1973196144 citedByCount "153" @default.
• W1973196144 countsByYear W19731961442012 @default.
• W1973196144 countsByYear W19731961442013 @default.
• W1973196144 countsByYear W19731961442014 @default.
• W1973196144 countsByYear W19731961442015 @default.
• W1973196144 countsByYear W19731961442016 @default.
• W1973196144 countsByYear W19731961442017 @default.
• W1973196144 countsByYear W19731961442018 @default.
• W1973196144 countsByYear W19731961442019 @default.
• W1973196144 countsByYear W19731961442020 @default.
• W1973196144 countsByYear W19731961442021 @default.
• W1973196144 countsByYear W19731961442022 @default.
• W1973196144 countsByYear W19731961442023 @default.
• W1973196144 crossrefType "journal-article" @default.
• W1973196144 hasAuthorship W1973196144A5003139041 @default.
• W1973196144 hasAuthorship W1973196144A5007320208 @default.
• W1973196144 hasAuthorship W1973196144A5018102939 @default.
• W1973196144 hasAuthorship W1973196144A5020050875 @default.
• W1973196144 hasAuthorship W1973196144A5067229912 @default.
• W1973196144 hasConcept C111429119 @default.
• W1973196144 hasConcept C120665830 @default.
• W1973196144 hasConcept C121332964 @default.
• W1973196144 hasConcept C124101348 @default.
• W1973196144 hasConcept C147789679 @default.
• W1973196144 hasConcept C15744967 @default.
• W1973196144 hasConcept C159467904 @default.
• W1973196144 hasConcept C177562468 @default.
• W1973196144 hasConcept C178790620 @default.
• W1973196144 hasConcept C181500209 @default.
• W1973196144 hasConcept C184779094 @default.
• W1973196144 hasConcept C185592680 @default.
• W1973196144 hasConcept C18705241 @default.
• W1973196144 hasConcept C2776029896 @default.
• W1973196144 hasConcept C2780009758 @default.
• W1973196144 hasConcept C32891209 @default.
• W1973196144 hasConcept C32909587 @default.
• W1973196144 hasConcept C41008148 @default.
• W1973196144 hasConcept C62520636 @default.
• W1973196144 hasConcept C66974803 @default.
• W1973196144 hasConcept C71240020 @default.
• W1973196144 hasConcept C77805123 @default.

• next