FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973215944> ?p ?o ?g. }

• W1973215944 endingPage "647" @default.
• W1973215944 startingPage "640" @default.
• W1973215944 abstract "The mechanism regulating primordial follicle formation remains largely unexplored because of the developmental particularity of female germ cells and their ultimate functional structure as follicles. Using an in vitro follicle reconstitution culture model, we explored, in the present study, the possibility of producing transgenetic follicles in vitro. We found that mouse fetal ovarian germ cells progressively lose the flexibility for gene manipulation with their oogonia-oocyte transformation upon entering meiosis, the borderline of which was at around embryonic age of 13.5 days post coitus (dpc). Interestingly, we further observed that fetal ovarian cells, only at this age or beyond achieve the capacity to reform the follicles in culture. Screening of well-known marker gene (Zp1-3, Figα, and Cx43) expression in cultured fetal ovarian cells of various developmental ages revealed that Figα is one of the determining factors for normal primordial follicle formation. By conducting reciprocal follicle reconstitution experiments, we provided further evidence that a synchronized germ-somatic cell interaction determines the normal duration of primordial folliculogenesis. Besides uncovering a potentially important regulatory mechanism for normal oocyte differentiation and follicle formation, this observation offers an alternative approach to produce transgenic oocytes/follicles, and thus animal models. J. Cell. Physiol. 208: 640–647, 2006. © 2006 Wiley-Liss, Inc." @default.
• W1973215944 created "2016-06-24" @default.
• W1973215944 creator A5019012025 @default.
• W1973215944 creator A5025006462 @default.
• W1973215944 creator A5025078654 @default.
• W1973215944 creator A5037789032 @default.
• W1973215944 creator A5039360390 @default.
• W1973215944 creator A5056484501 @default.
• W1973215944 creator A5086866538 @default.
• W1973215944 date "2006-09-01" @default.
• W1973215944 modified "2023-10-10" @default.
• W1973215944 title "Stage-specific germ-somatic cell interaction directs the primordial folliculogenesis in mouse fetal ovaries" @default.
• W1973215944 cites W1915101347 @default.
• W1973215944 cites W1961869750 @default.
• W1973215944 cites W1965062041 @default.
• W1973215944 cites W1973628165 @default.
• W1973215944 cites W1977135603 @default.
• W1973215944 cites W1991894106 @default.
• W1973215944 cites W1999100254 @default.
• W1973215944 cites W2018831893 @default.
• W1973215944 cites W2027924817 @default.
• W1973215944 cites W2050395183 @default.
• W1973215944 cites W2068868171 @default.
• W1973215944 cites W2069772488 @default.
• W1973215944 cites W2086778634 @default.
• W1973215944 cites W2089111937 @default.
• W1973215944 cites W2089543169 @default.
• W1973215944 cites W2099469606 @default.
• W1973215944 cites W2102351611 @default.
• W1973215944 cites W2102806129 @default.
• W1973215944 cites W2111265072 @default.
• W1973215944 cites W2118480433 @default.
• W1973215944 cites W2148563058 @default.
• W1973215944 cites W2168301890 @default.
• W1973215944 cites W2168337336 @default.
• W1973215944 cites W2351187645 @default.
• W1973215944 doi "https://doi.org/10.1002/jcp.20702" @default.
• W1973215944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16741957" @default.
• W1973215944 hasPublicationYear "2006" @default.
• W1973215944 type Work @default.
• W1973215944 sameAs 1973215944 @default.
• W1973215944 citedByCount "44" @default.
• W1973215944 countsByYear W19732159442012 @default.
• W1973215944 countsByYear W19732159442013 @default.
• W1973215944 countsByYear W19732159442014 @default.
• W1973215944 countsByYear W19732159442015 @default.
• W1973215944 countsByYear W19732159442016 @default.
• W1973215944 countsByYear W19732159442017 @default.
• W1973215944 countsByYear W19732159442018 @default.
• W1973215944 countsByYear W19732159442019 @default.
• W1973215944 countsByYear W19732159442021 @default.
• W1973215944 countsByYear W19732159442022 @default.
• W1973215944 countsByYear W19732159442023 @default.
• W1973215944 crossrefType "journal-article" @default.
• W1973215944 hasAuthorship W1973215944A5019012025 @default.
• W1973215944 hasAuthorship W1973215944A5025006462 @default.
• W1973215944 hasAuthorship W1973215944A5025078654 @default.
• W1973215944 hasAuthorship W1973215944A5037789032 @default.
• W1973215944 hasAuthorship W1973215944A5039360390 @default.
• W1973215944 hasAuthorship W1973215944A5056484501 @default.
• W1973215944 hasAuthorship W1973215944A5086866538 @default.
• W1973215944 hasConcept C102570824 @default.
• W1973215944 hasConcept C104317684 @default.
• W1973215944 hasConcept C126322002 @default.
• W1973215944 hasConcept C134018914 @default.
• W1973215944 hasConcept C134305767 @default.
• W1973215944 hasConcept C163949779 @default.
• W1973215944 hasConcept C16685009 @default.
• W1973215944 hasConcept C196843134 @default.
• W1973215944 hasConcept C2776690073 @default.
• W1973215944 hasConcept C2778324911 @default.
• W1973215944 hasConcept C2779122487 @default.
• W1973215944 hasConcept C2780536345 @default.
• W1973215944 hasConcept C54355233 @default.
• W1973215944 hasConcept C5512455 @default.
• W1973215944 hasConcept C71924100 @default.
• W1973215944 hasConcept C86803240 @default.
• W1973215944 hasConcept C87073359 @default.
• W1973215944 hasConcept C95444343 @default.
• W1973215944 hasConceptScore W1973215944C102570824 @default.
• W1973215944 hasConceptScore W1973215944C104317684 @default.
• W1973215944 hasConceptScore W1973215944C126322002 @default.
• W1973215944 hasConceptScore W1973215944C134018914 @default.
• W1973215944 hasConceptScore W1973215944C134305767 @default.
• W1973215944 hasConceptScore W1973215944C163949779 @default.
• W1973215944 hasConceptScore W1973215944C16685009 @default.
• W1973215944 hasConceptScore W1973215944C196843134 @default.
• W1973215944 hasConceptScore W1973215944C2776690073 @default.
• W1973215944 hasConceptScore W1973215944C2778324911 @default.
• W1973215944 hasConceptScore W1973215944C2779122487 @default.
• W1973215944 hasConceptScore W1973215944C2780536345 @default.
• W1973215944 hasConceptScore W1973215944C54355233 @default.
• W1973215944 hasConceptScore W1973215944C5512455 @default.
• W1973215944 hasConceptScore W1973215944C71924100 @default.
• W1973215944 hasConceptScore W1973215944C86803240 @default.
• W1973215944 hasConceptScore W1973215944C87073359 @default.
• W1973215944 hasConceptScore W1973215944C95444343 @default.
• W1973215944 hasIssue "3" @default.

• next