Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973238419> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W1973238419 endingPage "482" @default.
- W1973238419 startingPage "482" @default.
- W1973238419 abstract "Editorials1 September 1979Immunology and the Therapeutics of LeprosyWARD E. BULLOCK, M.D.WARD E. BULLOCK, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-91-3-482 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn infections caused by facultative or obligate intracellular microorganisms, anergy (loss of allergic response) is generally recognized as an ominous signal of the host's dwindling capacity to limit multiplication of the pathogen. This phenomenon is perhaps no better illustrated than in leprosy, still a serious problem worldwide for more than 12 million people. Anergy is observed most consistently in persons with lepromatous leprosy who typically are infected by an enormous number of bacilli, up to 1012. These persons consistently fail to manifest delayed-type hypersensitivity to intradermal challenge with antigens ofMycobacterium leprae. In addition, many of those with lepromatous disease...References1. BULLOCK W. Leprosy: a model of immunological perturbation in chronic infection. J Infect Dis. 1978;137:341-54. CrossrefMedlineGoogle Scholar2. GERSHON R. T-Cell control of antibody production. Contemp Top Immunobiol. 1973;3:1-40. Google Scholar3. WALDMANBRODER TS. Suppressor cells in the regulation of the immune response. Prog Clin Immunol. 1977;3:155-99. MedlineGoogle Scholar4. BULLOCKCARLSONGERSHON WER. The evolution of immunosuppressive cell populations in experimental mycobacterial infection. J Immunol. 1978;120:1709-16. MedlineGoogle Scholar5. HASTINGSJOB RC. Reversal reactions in lepromatous leprosy following transfer factor therapy. Am J Trop Med Hyg. 1978;27:995-1004. CrossrefMedlineGoogle Scholar6. LIMFUSAROGOOD SRR. Leprosy: VI. The treatment of leprosy patients with intravenous infusions of leukocytes from normal persons. Clin Immunol Immunopathol. 1972;1:122-39. CrossrefGoogle Scholar7. LOWEMCNULTY JF. The effect of BCG in lepromatous cases of leprosy. Int J Lepr. 1953;21:173-7. MedlineGoogle Scholar8. NATHNARAYANANMEHRASHARMAGUPTE IRNAM. Suppressor cells in human leprosy. Mexico City: XI International Leprosy Congress; 13-18 November 1978:77. Abstract. Google Scholar9. MEHRABLOOMMASONFIELDS VBLJ. Studies on Mycobacterium leprae-induced suppression of in vitro responses in leprosy patients. Mexico City: XI International Leprosy Congress; 13-18 November 1978:59 Abstract. Google Scholar10. KIRCHHEIMERSTORRS WE. Attempts to establish the armadillo (Dasypus novemcinctus Linn.) as a model for the study of leprosy: I. Report of lepromatoid leprosy in an experimentally infected armadillo. Int J Lepr. 1971;39:693-702. Google Scholar11. HARBOECLOSSBJUNEKRONVALLAXELSEN MOGGN. Mycobacterium leprae specific antibodies detected by radioimmunoassay. Scand J Immunol. 1978;7:111-20. CrossrefMedlineGoogle Scholar12. CALDWELLKIRCHHEIMERBUCHANAN HWT. Identification of a Mycobacterium leprae specific protein antigen and its possible application for the serodiagnosis of leprosy. Int J Lepr. 1979. In press. Google Scholar13. ABEIZUMISAITOMATHUR MSTS. Early serodiagnosis of leprosy by indirect immunofluorescence. Lepr India. 1976;48:272-6. MedlineGoogle Scholar14. PEARSONREESWATERS JRM. Sulphone resistance in leprosy: a review of one hundred proven clinical cases. Lancet. 1975;2:6972. Google Scholar15. REESWATERSPEARSONHELMYLAING RMJHA. Long-term treatment of dapsone-resistant leprosy with rifampicin: clinical and bacteriological studies. Int J Lepr. 1976;44:159-69. Google Scholar16. NOORDEEN S. Relapse in lepromatous leprosy. Lepr Rev. 1971;42:438. Google Scholar17. MEHRABLOOM VB. The induction of cell-mediated immunity to Mycobacterium leprae in the guinea pigs. Infect Immun. 1979;23:787-94. CrossrefMedlineGoogle Scholar18. TUNGKIMBJORVATNKRONVALLMCLARENWILLIAMS KBBGLR. Discrepancy between CIq deviation and raji cell tests in detection of circulating immune complexes in patients with leprosy. J Infect Dis. 1977;136:216-21. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine University of Kentucky College of Medicine Lexington, Kentucky PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByImmunology of Mycobacterial InfectionsTuberculosisLeprosy, an OverviewLeprosy (Hansen’s Disease)“Pro-eu-karyote” graft acceptance: A mechanism for intracellular parasitism — A new hypothesis for pathogenesis of leprosyThe Immunology of Mycobacterial Infections 1 September 1979Volume 91, Issue 3Page: 482-484KeywordsAllergy and immunologyAnergyAntigensHypersensitivityImmunologyInfectious diseasesIntracellular pathogensLeprosyMedical services Issue Published: 1 September 1979 PDF DownloadLoading ..." @default.
- W1973238419 created "2016-06-24" @default.
- W1973238419 creator A5017610390 @default.
- W1973238419 date "1979-09-01" @default.
- W1973238419 modified "2023-09-25" @default.
- W1973238419 title "Immunology and the Therapeutics of Leprosy" @default.
- W1973238419 cites W1592144279 @default.
- W1973238419 cites W159354068 @default.
- W1973238419 cites W1991720010 @default.
- W1973238419 cites W2043238772 @default.
- W1973238419 cites W2084964268 @default.
- W1973238419 cites W2240937424 @default.
- W1973238419 cites W2317076023 @default.
- W1973238419 cites W2336890179 @default.
- W1973238419 cites W2415764515 @default.
- W1973238419 cites W2419654628 @default.
- W1973238419 cites W2432889005 @default.
- W1973238419 cites W2469466446 @default.
- W1973238419 cites W265577697 @default.
- W1973238419 doi "https://doi.org/10.7326/0003-4819-91-3-482" @default.
- W1973238419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/382942" @default.
- W1973238419 hasPublicationYear "1979" @default.
- W1973238419 type Work @default.
- W1973238419 sameAs 1973238419 @default.
- W1973238419 citedByCount "7" @default.
- W1973238419 crossrefType "journal-article" @default.
- W1973238419 hasAuthorship W1973238419A5017610390 @default.
- W1973238419 hasConcept C126322002 @default.
- W1973238419 hasConcept C147483822 @default.
- W1973238419 hasConcept C203014093 @default.
- W1973238419 hasConcept C2779134260 @default.
- W1973238419 hasConcept C2779823659 @default.
- W1973238419 hasConcept C2779846462 @default.
- W1973238419 hasConcept C2780695269 @default.
- W1973238419 hasConcept C71924100 @default.
- W1973238419 hasConcept C8891405 @default.
- W1973238419 hasConceptScore W1973238419C126322002 @default.
- W1973238419 hasConceptScore W1973238419C147483822 @default.
- W1973238419 hasConceptScore W1973238419C203014093 @default.
- W1973238419 hasConceptScore W1973238419C2779134260 @default.
- W1973238419 hasConceptScore W1973238419C2779823659 @default.
- W1973238419 hasConceptScore W1973238419C2779846462 @default.
- W1973238419 hasConceptScore W1973238419C2780695269 @default.
- W1973238419 hasConceptScore W1973238419C71924100 @default.
- W1973238419 hasConceptScore W1973238419C8891405 @default.
- W1973238419 hasIssue "3" @default.
- W1973238419 hasLocation W19732384191 @default.
- W1973238419 hasLocation W19732384192 @default.
- W1973238419 hasOpenAccess W1973238419 @default.
- W1973238419 hasPrimaryLocation W19732384191 @default.
- W1973238419 hasRelatedWork W2078683391 @default.
- W1973238419 hasRelatedWork W2244947588 @default.
- W1973238419 hasRelatedWork W2248161976 @default.
- W1973238419 hasRelatedWork W2411848051 @default.
- W1973238419 hasRelatedWork W2442606681 @default.
- W1973238419 hasRelatedWork W2469970871 @default.
- W1973238419 hasRelatedWork W2470017242 @default.
- W1973238419 hasRelatedWork W2515266305 @default.
- W1973238419 hasRelatedWork W2591098767 @default.
- W1973238419 hasRelatedWork W8739296 @default.
- W1973238419 hasVolume "91" @default.
- W1973238419 isParatext "false" @default.
- W1973238419 isRetracted "false" @default.
- W1973238419 magId "1973238419" @default.
- W1973238419 workType "article" @default.