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- W1973241956 abstract "The aim of this study was to synthesize a series of ferrocenyl 4-aminoquinolines and to evaluate their activities against Plasmodium falciparum F32 (chloroquine-sensitive) and FCB1 and K1 (chloroquino-resistant). Some of the ferrocenyl compounds exhibited in vitro antiplasmodial activity in the nM range. In particular, (1R,4R)-N1-(7-chloroquinolin-4-yl)-N4-(ferrocenylmethyl)-N4-methylcyclohexane-1,4-diamine 17 presented the lowest IC50 value (26 nM) against CQ-resistant strains." @default.
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- W1973241956 date "2015-01-01" @default.
- W1973241956 modified "2023-09-28" @default.
- W1973241956 title "Synthesis and in vitro antiplasmodial activity of ferrocenyl aminoquinoline derivatives" @default.
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- W1973241956 doi "https://doi.org/10.1016/j.ejmech.2014.11.065" @default.
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