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- W1973265648 abstract "An optical fibre long period grating (LPG), modified with a coating of silica gold (SiO<sub>2</sub>:Au) core/shell nanoparticles (NPs) deposited using the layer-by-layer (LbL) method, was employed for the development of a bio-sensor. The SiO<sub>2</sub>:Au NPs were electrostatically assembled onto the LPG with the aid of a poly(hydrochloride ammonium) (PAH) polycation layer. The LPG sensor operates at the phase matching turning point to provide the highest sensitivity. The SiO<sub>2</sub>:Au NPs were modified with biotin, which was used as a ligand for streptavidin (SV) detection. The sensing mechanism is based on the measurement of the refractive index change induced by the binding of the SV to the biotin. The lowest detected concentration of SV was 19 nM using an LPG modified with a 3 layer (PAH/SiO<sub>2</sub>:Au) thin film." @default.
- W1973265648 created "2016-06-24" @default.
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- W1973265648 date "2014-06-02" @default.
- W1973265648 modified "2023-09-23" @default.
- W1973265648 title "Sensitive protein detection using an optical fibre long period grating sensor anchored with silica core gold shell nanoparticles" @default.
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- W1973265648 doi "https://doi.org/10.1117/12.2059196" @default.
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