FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973282816> ?p ?o ?g. }

• W1973282816 endingPage "295" @default.
• W1973282816 startingPage "286" @default.
• W1973282816 abstract "The phenylpropanoid pathway in plants leads to the synthesis of a wide range of soluble secondary metabolites, many of which accumulate as glycosides. In Arabidopsis, a small cluster of three closely related genes, UGT72E1–E3, encode glycosyltransferases shown to glucosylate several phenylpropanoids in vitro, including monolignols, hydroxycinnamic acids and hydroxycinnamic aldehydes. The role of these genes in planta has now been investigated through genetically downregulating the expression of individual genes or silencing the entire cluster. Analysis of these transgenic Arabidopsis plants showed that the levels of coniferyl and sinapyl alcohol 4-O-glucosides that accumulate in light-grown roots were significantly reduced. A 50% reduction in both glucosides was observed in plants in which UGT72E2 was downregulated, whereas silencing the three genes led to a 90% reduction, suggesting some redundancy of function within the cluster. The gene encoding UGT72E2 was constitutively overexpressed in transgenic Arabidopsis to determine whether increased glucosylation of monolignols could influence flux through the soluble phenylpropanoid pathway. Elevated expression of UGT72E2 led to increased accumulation of monolignol glucosides in root tissues and also the appearance of these glucosides in leaves. In particular, coniferyl alcohol 4-O-glucoside accumulated to massive amounts (10 μmol g−1 FW) in root tissues of these plants. Increased glucosylation of other phenylpropanoids also occurred in plants overexpressing this glycosyltransferase. Significantly changing the pattern of glycosides in the leaves also led to a pronounced change in accumulation of the hydroxycinnamic ester sinapoyl malate. The data demonstrate the plasticity of phenylpropanoid metabolism and the important role that glucosylation of secondary metabolites can play in cellular homeostasis." @default.
• W1973282816 created "2016-06-24" @default.
• W1973282816 creator A5001631398 @default.
• W1973282816 creator A5003601738 @default.
• W1973282816 creator A5018685252 @default.
• W1973282816 creator A5028097580 @default.
• W1973282816 creator A5057323986 @default.
• W1973282816 creator A5059586593 @default.
• W1973282816 creator A5063088047 @default.
• W1973282816 creator A5082200216 @default.
• W1973282816 date "2006-10-01" @default.
• W1973282816 modified "2023-09-27" @default.
• W1973282816 title "The glucosyltransferase UGT72E2 is responsible for monolignol 4-<i>O</i>-glucoside production in<i>Arabidopsis thaliana</i>" @default.
• W1973282816 cites W1555036163 @default.
• W1973282816 cites W1965879701 @default.
• W1973282816 cites W1970342847 @default.
• W1973282816 cites W1974987683 @default.
• W1973282816 cites W1991721460 @default.
• W1973282816 cites W1994079191 @default.
• W1973282816 cites W1998819058 @default.
• W1973282816 cites W2004177901 @default.
• W1973282816 cites W2004608143 @default.
• W1973282816 cites W2010726741 @default.
• W1973282816 cites W2021372819 @default.
• W1973282816 cites W2022965367 @default.
• W1973282816 cites W2024556021 @default.
• W1973282816 cites W2024820625 @default.
• W1973282816 cites W2028556319 @default.
• W1973282816 cites W2039807203 @default.
• W1973282816 cites W2040891760 @default.
• W1973282816 cites W2044037261 @default.
• W1973282816 cites W2049379345 @default.
• W1973282816 cites W2071198352 @default.
• W1973282816 cites W2103230217 @default.
• W1973282816 cites W2108781956 @default.
• W1973282816 cites W2116122104 @default.
• W1973282816 cites W2117880514 @default.
• W1973282816 cites W2124697128 @default.
• W1973282816 cites W2127151407 @default.
• W1973282816 cites W2128946743 @default.
• W1973282816 cites W2129746249 @default.
• W1973282816 cites W2131988837 @default.
• W1973282816 cites W2134038950 @default.
• W1973282816 cites W2149661178 @default.
• W1973282816 cites W2156558804 @default.
• W1973282816 cites W2171014698 @default.
• W1973282816 cites W4242137597 @default.
• W1973282816 doi "https://doi.org/10.1111/j.1365-313x.2006.02872.x" @default.
• W1973282816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16995900" @default.
• W1973282816 hasPublicationYear "2006" @default.
• W1973282816 type Work @default.
• W1973282816 sameAs 1973282816 @default.
• W1973282816 citedByCount "108" @default.
• W1973282816 countsByYear W19732828162012 @default.
• W1973282816 countsByYear W19732828162013 @default.
• W1973282816 countsByYear W19732828162014 @default.
• W1973282816 countsByYear W19732828162015 @default.
• W1973282816 countsByYear W19732828162016 @default.
• W1973282816 countsByYear W19732828162017 @default.
• W1973282816 countsByYear W19732828162018 @default.
• W1973282816 countsByYear W19732828162019 @default.
• W1973282816 countsByYear W19732828162020 @default.
• W1973282816 countsByYear W19732828162021 @default.
• W1973282816 countsByYear W19732828162022 @default.
• W1973282816 countsByYear W19732828162023 @default.
• W1973282816 crossrefType "journal-article" @default.
• W1973282816 hasAuthorship W1973282816A5001631398 @default.
• W1973282816 hasAuthorship W1973282816A5003601738 @default.
• W1973282816 hasAuthorship W1973282816A5018685252 @default.
• W1973282816 hasAuthorship W1973282816A5028097580 @default.
• W1973282816 hasAuthorship W1973282816A5057323986 @default.
• W1973282816 hasAuthorship W1973282816A5059586593 @default.
• W1973282816 hasAuthorship W1973282816A5063088047 @default.
• W1973282816 hasAuthorship W1973282816A5082200216 @default.
• W1973282816 hasBestOaLocation W19732828161 @default.
• W1973282816 hasConcept C104317684 @default.
• W1973282816 hasConcept C142724271 @default.
• W1973282816 hasConcept C143065580 @default.
• W1973282816 hasConcept C181199279 @default.
• W1973282816 hasConcept C204787440 @default.
• W1973282816 hasConcept C2775988993 @default.
• W1973282816 hasConcept C2776559899 @default.
• W1973282816 hasConcept C2778004101 @default.
• W1973282816 hasConcept C2779491563 @default.
• W1973282816 hasConcept C2780194770 @default.
• W1973282816 hasConcept C2780678855 @default.
• W1973282816 hasConcept C2780753511 @default.
• W1973282816 hasConcept C2781347565 @default.
• W1973282816 hasConcept C553450214 @default.
• W1973282816 hasConcept C55493867 @default.
• W1973282816 hasConcept C59822182 @default.
• W1973282816 hasConcept C71924100 @default.
• W1973282816 hasConcept C86803240 @default.
• W1973282816 hasConceptScore W1973282816C104317684 @default.
• W1973282816 hasConceptScore W1973282816C142724271 @default.
• W1973282816 hasConceptScore W1973282816C143065580 @default.
• W1973282816 hasConceptScore W1973282816C181199279 @default.
• W1973282816 hasConceptScore W1973282816C204787440 @default.

• next