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• W1973287769 abstract "The NADPH oxidase is an electron transport chain found in lymphocytes and in the wall of the endocytic vacuole of 'professional' phagocytic cells. It is so called because NADPH is used as an electron donor to reduce oxygen to superoxide and hydrogen peroxide. The redox components are provided by a very unusual flavocytochrome b from the membrane, which is dependent upon cytosolic factors (including two specialized proteins, p47phox and p67phox) for activation. The small GTP-binding protein, p21rac, is also implicated in this system, possibly as the switch that triggers electron transport. This system provides a key to our understanding of the way in which these GTP-binding proteins function." @default.
• W1973287769 created "2016-06-24" @default.
• W1973287769 creator A5025311351 @default.
• W1973287769 creator A5063481128 @default.
• W1973287769 date "1993-02-01" @default.
• W1973287769 modified "2023-10-10" @default.
• W1973287769 title "The biochemical basis of the NADPH oxidase of phagocytes" @default.
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• W1973287769 doi "https://doi.org/10.1016/0968-0004(93)90051-n" @default.
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