FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973294355> ?p ?o ?g. }

• W1973294355 endingPage "e51068" @default.
• W1973294355 startingPage "e51068" @default.
• W1973294355 abstract "Influenza virus (InfV) infection during pregnancy is a known risk factor for neurodevelopment abnormalities in the offspring, including the risk of schizophrenia, and has been shown to result in an abnormal behavioral phenotype in mice. However, previous reports have concentrated on neuroadapted influenza strains, whereas increased schizophrenia risk is associated with common respiratory InfV. In addition, no specific mechanism has been proposed for the actions of maternal infection on the developing brain that could account for schizophrenia risk. We identified two common isolates from the community with antigenic configurations H3N2 and H1N1 and compared their effects on developing brain with a mouse modified-strain A/WSN/33 specifically on the developing of dopaminergic neurons. We found that H1N1 InfV have high affinity for dopaminergic neurons in vitro, leading to nuclear factor kappa B activation and apoptosis. Furthermore, prenatal infection of mothers with the same strains results in loss of dopaminergic neurons in the offspring, and in an abnormal behavioral phenotype. We propose that the well-known contribution of InfV to risk of schizophrenia during development may involve a similar specific mechanism and discuss evidence from the literature in relation to this hypothesis." @default.
• W1973294355 created "2016-06-24" @default.
• W1973294355 creator A5003049946 @default.
• W1973294355 creator A5004706412 @default.
• W1973294355 creator A5008359743 @default.
• W1973294355 creator A5015126803 @default.
• W1973294355 creator A5016688715 @default.
• W1973294355 creator A5016739444 @default.
• W1973294355 creator A5041600848 @default.
• W1973294355 creator A5049007006 @default.
• W1973294355 creator A5058544922 @default.
• W1973294355 creator A5072229651 @default.
• W1973294355 creator A5078347127 @default.
• W1973294355 creator A5079836554 @default.
• W1973294355 creator A5088528076 @default.
• W1973294355 date "2012-12-10" @default.
• W1973294355 modified "2023-10-18" @default.
• W1973294355 title "Effects of Two Commonly Found Strains of Influenza A Virus on Developing Dopaminergic Neurons, in Relation to the Pathophysiology of Schizophrenia" @default.
• W1973294355 cites W1593077970 @default.
• W1973294355 cites W1606002920 @default.
• W1973294355 cites W162098332 @default.
• W1973294355 cites W1963626598 @default.
• W1973294355 cites W1969179247 @default.
• W1973294355 cites W1970456763 @default.
• W1973294355 cites W1978008404 @default.
• W1973294355 cites W1981631090 @default.
• W1973294355 cites W1981729889 @default.
• W1973294355 cites W1990999239 @default.
• W1973294355 cites W2004275727 @default.
• W1973294355 cites W2005638680 @default.
• W1973294355 cites W2032037877 @default.
• W1973294355 cites W2032866243 @default.
• W1973294355 cites W2033880528 @default.
• W1973294355 cites W2039926615 @default.
• W1973294355 cites W2040789766 @default.
• W1973294355 cites W2049309555 @default.
• W1973294355 cites W2056134923 @default.
• W1973294355 cites W2068111891 @default.
• W1973294355 cites W2075102897 @default.
• W1973294355 cites W2076545903 @default.
• W1973294355 cites W2078990597 @default.
• W1973294355 cites W2082434791 @default.
• W1973294355 cites W2086167675 @default.
• W1973294355 cites W2086662279 @default.
• W1973294355 cites W2095212000 @default.
• W1973294355 cites W2101964018 @default.
• W1973294355 cites W2102291283 @default.
• W1973294355 cites W2119855769 @default.
• W1973294355 cites W2122918016 @default.
• W1973294355 cites W2126691046 @default.
• W1973294355 cites W2130620798 @default.
• W1973294355 cites W2131200439 @default.
• W1973294355 cites W2138987068 @default.
• W1973294355 cites W2140164106 @default.
• W1973294355 cites W2143217444 @default.
• W1973294355 cites W2147080256 @default.
• W1973294355 cites W2156227125 @default.
• W1973294355 cites W2157092444 @default.
• W1973294355 cites W2171435204 @default.
• W1973294355 cites W2272731271 @default.
• W1973294355 cites W2328409603 @default.
• W1973294355 cites W2472388925 @default.
• W1973294355 doi "https://doi.org/10.1371/journal.pone.0051068" @default.
• W1973294355 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3519479" @default.
• W1973294355 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23251423" @default.
• W1973294355 hasPublicationYear "2012" @default.
• W1973294355 type Work @default.
• W1973294355 sameAs 1973294355 @default.
• W1973294355 citedByCount "26" @default.
• W1973294355 countsByYear W19732943552013 @default.
• W1973294355 countsByYear W19732943552014 @default.
• W1973294355 countsByYear W19732943552015 @default.
• W1973294355 countsByYear W19732943552017 @default.
• W1973294355 countsByYear W19732943552018 @default.
• W1973294355 countsByYear W19732943552019 @default.
• W1973294355 countsByYear W19732943552020 @default.
• W1973294355 countsByYear W19732943552021 @default.
• W1973294355 countsByYear W19732943552022 @default.
• W1973294355 countsByYear W19732943552023 @default.
• W1973294355 crossrefType "journal-article" @default.
• W1973294355 hasAuthorship W1973294355A5003049946 @default.
• W1973294355 hasAuthorship W1973294355A5004706412 @default.
• W1973294355 hasAuthorship W1973294355A5008359743 @default.
• W1973294355 hasAuthorship W1973294355A5015126803 @default.
• W1973294355 hasAuthorship W1973294355A5016688715 @default.
• W1973294355 hasAuthorship W1973294355A5016739444 @default.
• W1973294355 hasAuthorship W1973294355A5041600848 @default.
• W1973294355 hasAuthorship W1973294355A5049007006 @default.
• W1973294355 hasAuthorship W1973294355A5058544922 @default.
• W1973294355 hasAuthorship W1973294355A5072229651 @default.
• W1973294355 hasAuthorship W1973294355A5078347127 @default.
• W1973294355 hasAuthorship W1973294355A5079836554 @default.
• W1973294355 hasAuthorship W1973294355A5088528076 @default.
• W1973294355 hasBestOaLocation W19732943551 @default.
• W1973294355 hasConcept C10162356 @default.
• W1973294355 hasConcept C104317684 @default.
• W1973294355 hasConcept C111472728 @default.
• W1973294355 hasConcept C112672928 @default.

• next