FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973303492> ?p ?o ?g. }

• W1973303492 endingPage "182" @default.
• W1973303492 startingPage "176" @default.
• W1973303492 abstract "Severe iron deficiency requires intravenous iron supplementation to replenish iron stores. Intravenous iron sucrose has been used for decades for the treatment of anemia. New generic iron sucrose products are now marketed for the use in several countries and there is an ongoing discussion about the safety and efficacy of iron sucrose similars.In this study, we compared the iron sucrose originator Venofer® and the generic iron sucrose AZAD (ISA) regarding bioavailability, toxicity and stability in human THP-1 cells and HepG2 cells.The bioavailability of Venofer® and ISA was investigated in both cell types by a ferrozin-based assay. The release of incorporated iron was assayed by atomic absorption spectroscopy. Ferritin content was measured by enzyme-linked immunosorbent assay (ELISA). HepG2 cells were used to investigate the intracellular labile iron pool (LIP), which was measured by the fluorescent calcein assay. The amount of redox-active iron within the iron formulations was assayed using fluorescent dichlorofluorescein.We found no significant differences in all parameters between Venofer® and ISA in regard of bioavailability, toxicity and stability in vitro.ISA shows identical physico-chemical features and identical bioavailability in vitro. This study is a profound basis for future clinical tests with generic iron sucrose compounds." @default.
• W1973303492 created "2016-06-24" @default.
• W1973303492 creator A5005785494 @default.
• W1973303492 creator A5006953928 @default.
• W1973303492 creator A5017665636 @default.
• W1973303492 creator A5023910112 @default.
• W1973303492 creator A5032206643 @default.
• W1973303492 creator A5083310976 @default.
• W1973303492 date "2013-11-13" @default.
• W1973303492 modified "2023-10-16" @default.
• W1973303492 title "Bioavailability and stability of intravenous iron sucrose originator versus generic iron sucrose AZAD" @default.
• W1973303492 cites W1489844805 @default.
• W1973303492 cites W1538196126 @default.
• W1973303492 cites W1582436864 @default.
• W1973303492 cites W1734082729 @default.
• W1973303492 cites W1882486138 @default.
• W1973303492 cites W1968699973 @default.
• W1973303492 cites W1973382529 @default.
• W1973303492 cites W1979497202 @default.
• W1973303492 cites W2001408672 @default.
• W1973303492 cites W2004597391 @default.
• W1973303492 cites W2017197748 @default.
• W1973303492 cites W2027317491 @default.
• W1973303492 cites W2058461412 @default.
• W1973303492 cites W2064620980 @default.
• W1973303492 cites W2068337287 @default.
• W1973303492 cites W2072068953 @default.
• W1973303492 cites W2084508510 @default.
• W1973303492 cites W2086438722 @default.
• W1973303492 cites W2094883077 @default.
• W1973303492 cites W2105608359 @default.
• W1973303492 cites W2113015908 @default.
• W1973303492 cites W2125134781 @default.
• W1973303492 cites W2125959031 @default.
• W1973303492 cites W2134959109 @default.
• W1973303492 cites W2145087737 @default.
• W1973303492 cites W2155878409 @default.
• W1973303492 cites W2159335944 @default.
• W1973303492 cites W2172239347 @default.
• W1973303492 cites W2318478822 @default.
• W1973303492 cites W2400314058 @default.
• W1973303492 doi "https://doi.org/10.3109/10837450.2013.852575" @default.
• W1973303492 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24219061" @default.
• W1973303492 hasPublicationYear "2013" @default.
• W1973303492 type Work @default.
• W1973303492 sameAs 1973303492 @default.
• W1973303492 citedByCount "6" @default.
• W1973303492 countsByYear W19733034922014 @default.
• W1973303492 countsByYear W19733034922017 @default.
• W1973303492 countsByYear W19733034922018 @default.
• W1973303492 countsByYear W19733034922022 @default.
• W1973303492 countsByYear W19733034922023 @default.
• W1973303492 crossrefType "journal-article" @default.
• W1973303492 hasAuthorship W1973303492A5005785494 @default.
• W1973303492 hasAuthorship W1973303492A5006953928 @default.
• W1973303492 hasAuthorship W1973303492A5017665636 @default.
• W1973303492 hasAuthorship W1973303492A5023910112 @default.
• W1973303492 hasAuthorship W1973303492A5032206643 @default.
• W1973303492 hasAuthorship W1973303492A5083310976 @default.
• W1973303492 hasConcept C126322002 @default.
• W1973303492 hasConcept C178790620 @default.
• W1973303492 hasConcept C181389837 @default.
• W1973303492 hasConcept C185592680 @default.
• W1973303492 hasConcept C2776974161 @default.
• W1973303492 hasConcept C2777417653 @default.
• W1973303492 hasConcept C2778248108 @default.
• W1973303492 hasConcept C2778319317 @default.
• W1973303492 hasConcept C2778597767 @default.
• W1973303492 hasConcept C29730261 @default.
• W1973303492 hasConcept C3020614022 @default.
• W1973303492 hasConcept C55493867 @default.
• W1973303492 hasConcept C71924100 @default.
• W1973303492 hasConcept C86803240 @default.
• W1973303492 hasConcept C98274493 @default.
• W1973303492 hasConceptScore W1973303492C126322002 @default.
• W1973303492 hasConceptScore W1973303492C178790620 @default.
• W1973303492 hasConceptScore W1973303492C181389837 @default.
• W1973303492 hasConceptScore W1973303492C185592680 @default.
• W1973303492 hasConceptScore W1973303492C2776974161 @default.
• W1973303492 hasConceptScore W1973303492C2777417653 @default.
• W1973303492 hasConceptScore W1973303492C2778248108 @default.
• W1973303492 hasConceptScore W1973303492C2778319317 @default.
• W1973303492 hasConceptScore W1973303492C2778597767 @default.
• W1973303492 hasConceptScore W1973303492C29730261 @default.
• W1973303492 hasConceptScore W1973303492C3020614022 @default.
• W1973303492 hasConceptScore W1973303492C55493867 @default.
• W1973303492 hasConceptScore W1973303492C71924100 @default.
• W1973303492 hasConceptScore W1973303492C86803240 @default.
• W1973303492 hasConceptScore W1973303492C98274493 @default.
• W1973303492 hasIssue "2" @default.
• W1973303492 hasLocation W19733034921 @default.
• W1973303492 hasLocation W19733034922 @default.
• W1973303492 hasOpenAccess W1973303492 @default.
• W1973303492 hasPrimaryLocation W19733034921 @default.
• W1973303492 hasRelatedWork W1973303492 @default.
• W1973303492 hasRelatedWork W2030492114 @default.
• W1973303492 hasRelatedWork W2363740212 @default.
• W1973303492 hasRelatedWork W2383167596 @default.

• next