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- W1973382111 abstract "Background: Differences in opinion exist among researchers in relation to the course and outcome of substance abuse co-morbidity in schizophrenia. Aim: To compare the pattern of remission of symptoms in positive and negative schizophrenics with and without a history of substance abuse. Methods: Seventy schizophrenics were divided into two groups based on the history of presence or absence of substance abuse/dependence. Thirty-eight patients (54.3%) were diagnosed as having co-morbid alcohol/ substance abuse/dependence. Patients were rated at two-weekly intervals on the Positive and Negative Syndrome Scale (PANSS) with one follow-up rating by the end of the third month. Co-morbid substance abusers were predominantly represented by a positive syndrome and non-abusers by a negative syndrome at the time of admission. Results: Psychopathology remitted much faster in the substance-abusing group but after discharge, these patients tend to return to their pre-admission state. Conclusion: The following hypothesis is proposed based on the findings of the present study: 'Short-term inpatient outcome of substance-abusing schizophrenics is significantly better than non-substance abusing schizophrenics because of the faster rate of remission of their symptoms.' A corollary to the above hypothesis may be evolved-'through intense inpatient follow-up one may be able to differentiate substance-abusing and non-abusing schizophrenics'." @default.
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- W1973382111 date "2005-01-01" @default.
- W1973382111 modified "2023-09-23" @default.
- W1973382111 title "Substance abuse co-morbidity in schizophrenia: An inpatient study of course and outcome" @default.
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- W1973382111 doi "https://doi.org/10.4103/0019-5545.46072" @default.
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