Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973403006> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1973403006 endingPage "118" @default.
- W1973403006 startingPage "112" @default.
- W1973403006 abstract "Abstract Photooxidation of 6-phosphogluconate dehydrogenase in the presence of pyridoxal 5′-phosphate (which binds reversibly to a lysine residue at the active center) leads to an irreversible loss of the enzymatic activity. Loss of activity follows first-order kinetics. Photoinactivation was correlated with the specific destruction of only two histidine residues. Binding to the active center lysine seems to be a requisite for the efficiency of the pyridoxal phosphate as a photoinactivating agent. Pyridoxal, which does not react with this lysine residue, is ineffective as photosensitizer. The substrate 6-phosphogluconate prevents the binding of the pyridoxal phosphate and protects against photoinactivation. These findings suggest that pyridoxal phosphate may be useful as a specific photosensitizer for those enzymes which are inhibited by specific binding with this compound." @default.
- W1973403006 created "2016-06-24" @default.
- W1973403006 creator A5030915444 @default.
- W1973403006 creator A5083629284 @default.
- W1973403006 date "1969-08-01" @default.
- W1973403006 modified "2023-10-11" @default.
- W1973403006 title "Pyridoxal 5′-phosphate as a specific photosensitizer for histidine residue at the active site of 6-phosphogluconate dehydrogenase" @default.
- W1973403006 cites W1542719245 @default.
- W1973403006 cites W1574291960 @default.
- W1973403006 cites W1592248958 @default.
- W1973403006 cites W1980154942 @default.
- W1973403006 cites W2007471562 @default.
- W1973403006 cites W2017470279 @default.
- W1973403006 cites W2020691792 @default.
- W1973403006 cites W2026325914 @default.
- W1973403006 cites W2077518468 @default.
- W1973403006 cites W2305449604 @default.
- W1973403006 cites W2333363395 @default.
- W1973403006 cites W4233910202 @default.
- W1973403006 cites W77951017 @default.
- W1973403006 cites W91837625 @default.
- W1973403006 doi "https://doi.org/10.1016/0003-9861(69)90494-9" @default.
- W1973403006 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5810823" @default.
- W1973403006 hasPublicationYear "1969" @default.
- W1973403006 type Work @default.
- W1973403006 sameAs 1973403006 @default.
- W1973403006 citedByCount "63" @default.
- W1973403006 countsByYear W19734030062018 @default.
- W1973403006 countsByYear W19734030062019 @default.
- W1973403006 countsByYear W19734030062021 @default.
- W1973403006 countsByYear W19734030062022 @default.
- W1973403006 crossrefType "journal-article" @default.
- W1973403006 hasAuthorship W1973403006A5030915444 @default.
- W1973403006 hasAuthorship W1973403006A5083629284 @default.
- W1973403006 hasConcept C181199279 @default.
- W1973403006 hasConcept C185592680 @default.
- W1973403006 hasConcept C192233252 @default.
- W1973403006 hasConcept C197957613 @default.
- W1973403006 hasConcept C2776317432 @default.
- W1973403006 hasConcept C2776834122 @default.
- W1973403006 hasConcept C2777132085 @default.
- W1973403006 hasConcept C2778460671 @default.
- W1973403006 hasConcept C2780859938 @default.
- W1973403006 hasConcept C2781338088 @default.
- W1973403006 hasConcept C2781469039 @default.
- W1973403006 hasConcept C2910491791 @default.
- W1973403006 hasConcept C41183919 @default.
- W1973403006 hasConcept C55493867 @default.
- W1973403006 hasConcept C75473681 @default.
- W1973403006 hasConceptScore W1973403006C181199279 @default.
- W1973403006 hasConceptScore W1973403006C185592680 @default.
- W1973403006 hasConceptScore W1973403006C192233252 @default.
- W1973403006 hasConceptScore W1973403006C197957613 @default.
- W1973403006 hasConceptScore W1973403006C2776317432 @default.
- W1973403006 hasConceptScore W1973403006C2776834122 @default.
- W1973403006 hasConceptScore W1973403006C2777132085 @default.
- W1973403006 hasConceptScore W1973403006C2778460671 @default.
- W1973403006 hasConceptScore W1973403006C2780859938 @default.
- W1973403006 hasConceptScore W1973403006C2781338088 @default.
- W1973403006 hasConceptScore W1973403006C2781469039 @default.
- W1973403006 hasConceptScore W1973403006C2910491791 @default.
- W1973403006 hasConceptScore W1973403006C41183919 @default.
- W1973403006 hasConceptScore W1973403006C55493867 @default.
- W1973403006 hasConceptScore W1973403006C75473681 @default.
- W1973403006 hasIssue "1" @default.
- W1973403006 hasLocation W19734030061 @default.
- W1973403006 hasLocation W19734030062 @default.
- W1973403006 hasOpenAccess W1973403006 @default.
- W1973403006 hasPrimaryLocation W19734030061 @default.
- W1973403006 hasRelatedWork W1676123380 @default.
- W1973403006 hasRelatedWork W1970678982 @default.
- W1973403006 hasRelatedWork W1977032778 @default.
- W1973403006 hasRelatedWork W2074082269 @default.
- W1973403006 hasRelatedWork W2079996124 @default.
- W1973403006 hasRelatedWork W2320845031 @default.
- W1973403006 hasRelatedWork W2409347968 @default.
- W1973403006 hasRelatedWork W2480973654 @default.
- W1973403006 hasRelatedWork W4234262745 @default.
- W1973403006 hasRelatedWork W4235629637 @default.
- W1973403006 hasVolume "133" @default.
- W1973403006 isParatext "false" @default.
- W1973403006 isRetracted "false" @default.
- W1973403006 magId "1973403006" @default.
- W1973403006 workType "article" @default.