Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973409056> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1973409056 endingPage "196" @default.
- W1973409056 startingPage "191" @default.
- W1973409056 abstract "It was observed that orotic acid (OA), a precursor for pyrimidine nucleotide biosynthesis, when supplied exogenously at 1% level in the diet selectively stimulated the growth of hepatocytes modified by 1,2-dimethylhydrazine (1,2-DMH) to form gamma-glutamyltransferase (gamma-GT) (EC 2.3.2.2) positive islands. Increasing the duration of OA diet from 5 to 10 weeks resulted in an increase in the number of foci from 6 to 14/cm2. Rats that received the carcinogen and basal diet, however, developed only 1-2 foci/cm2. This unique effect of OA can be further accentuated by supplying a liver cell proliferative stimulus, such as a single necrogenic dose of CCl4." @default.
- W1973409056 created "2016-06-24" @default.
- W1973409056 creator A5014841906 @default.
- W1973409056 creator A5019517802 @default.
- W1973409056 creator A5022482403 @default.
- W1973409056 creator A5024911981 @default.
- W1973409056 creator A5061961269 @default.
- W1973409056 date "1982-07-01" @default.
- W1973409056 modified "2023-09-24" @default.
- W1973409056 title "Dietary orotic acid, a new selective growth stimulus for carcinogen altered hepatocytes in rat☆" @default.
- W1973409056 cites W1486100519 @default.
- W1973409056 cites W1558322086 @default.
- W1973409056 cites W1599981134 @default.
- W1973409056 cites W1748388582 @default.
- W1973409056 cites W1833104984 @default.
- W1973409056 cites W1886089146 @default.
- W1973409056 cites W1902704469 @default.
- W1973409056 cites W1979870899 @default.
- W1973409056 cites W2025622366 @default.
- W1973409056 cites W2070256254 @default.
- W1973409056 cites W2087582070 @default.
- W1973409056 cites W2152658714 @default.
- W1973409056 cites W2290169940 @default.
- W1973409056 cites W2401276945 @default.
- W1973409056 cites W2412099651 @default.
- W1973409056 cites W2419250222 @default.
- W1973409056 cites W77466315 @default.
- W1973409056 doi "https://doi.org/10.1016/0304-3835(82)90060-x" @default.
- W1973409056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6127157" @default.
- W1973409056 hasPublicationYear "1982" @default.
- W1973409056 type Work @default.
- W1973409056 sameAs 1973409056 @default.
- W1973409056 citedByCount "34" @default.
- W1973409056 countsByYear W19734090562012 @default.
- W1973409056 countsByYear W19734090562019 @default.
- W1973409056 countsByYear W19734090562021 @default.
- W1973409056 crossrefType "journal-article" @default.
- W1973409056 hasAuthorship W1973409056A5014841906 @default.
- W1973409056 hasAuthorship W1973409056A5019517802 @default.
- W1973409056 hasAuthorship W1973409056A5022482403 @default.
- W1973409056 hasAuthorship W1973409056A5024911981 @default.
- W1973409056 hasAuthorship W1973409056A5061961269 @default.
- W1973409056 hasConcept C114246631 @default.
- W1973409056 hasConcept C126322002 @default.
- W1973409056 hasConcept C134018914 @default.
- W1973409056 hasConcept C15744967 @default.
- W1973409056 hasConcept C185592680 @default.
- W1973409056 hasConcept C202751555 @default.
- W1973409056 hasConcept C2775851010 @default.
- W1973409056 hasConcept C2776200302 @default.
- W1973409056 hasConcept C2779918689 @default.
- W1973409056 hasConcept C542102704 @default.
- W1973409056 hasConcept C55493867 @default.
- W1973409056 hasConcept C62112901 @default.
- W1973409056 hasConcept C71924100 @default.
- W1973409056 hasConcept C86803240 @default.
- W1973409056 hasConceptScore W1973409056C114246631 @default.
- W1973409056 hasConceptScore W1973409056C126322002 @default.
- W1973409056 hasConceptScore W1973409056C134018914 @default.
- W1973409056 hasConceptScore W1973409056C15744967 @default.
- W1973409056 hasConceptScore W1973409056C185592680 @default.
- W1973409056 hasConceptScore W1973409056C202751555 @default.
- W1973409056 hasConceptScore W1973409056C2775851010 @default.
- W1973409056 hasConceptScore W1973409056C2776200302 @default.
- W1973409056 hasConceptScore W1973409056C2779918689 @default.
- W1973409056 hasConceptScore W1973409056C542102704 @default.
- W1973409056 hasConceptScore W1973409056C55493867 @default.
- W1973409056 hasConceptScore W1973409056C62112901 @default.
- W1973409056 hasConceptScore W1973409056C71924100 @default.
- W1973409056 hasConceptScore W1973409056C86803240 @default.
- W1973409056 hasIssue "2" @default.
- W1973409056 hasLocation W19734090561 @default.
- W1973409056 hasLocation W19734090562 @default.
- W1973409056 hasOpenAccess W1973409056 @default.
- W1973409056 hasPrimaryLocation W19734090561 @default.
- W1973409056 hasRelatedWork W1581333745 @default.
- W1973409056 hasRelatedWork W1855195526 @default.
- W1973409056 hasRelatedWork W1921357624 @default.
- W1973409056 hasRelatedWork W2044988659 @default.
- W1973409056 hasRelatedWork W2094423915 @default.
- W1973409056 hasRelatedWork W2121100406 @default.
- W1973409056 hasRelatedWork W2151391157 @default.
- W1973409056 hasRelatedWork W2466450716 @default.
- W1973409056 hasRelatedWork W2748952813 @default.
- W1973409056 hasRelatedWork W2337002345 @default.
- W1973409056 hasVolume "16" @default.
- W1973409056 isParatext "false" @default.
- W1973409056 isRetracted "false" @default.
- W1973409056 magId "1973409056" @default.
- W1973409056 workType "article" @default.