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- W1973456114 abstract "Dispiro 1,2,4-trioxanes and 1,2,4,5-tetraoxanes had superior efficacy against Fasciola hepatica than the corresponding ozonides (1,2,4-trioxolanes). For highest efficacy, spiroadamantane and carboxymethyl substructures were required. Three compounds completely cured F. hepatica-infected mice at single oral doses of 50 mg/kg and two were partially curative at single doses of 25 mg/kg." @default.
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- W1973456114 date "2011-09-01" @default.
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- W1973456114 title "The activity of dispiro peroxides against Fasciola hepatica" @default.
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- W1973456114 doi "https://doi.org/10.1016/j.bmcl.2011.07.024" @default.
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