Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973457876> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W1973457876 abstract "Syntheses of spiro[2,3-dihydro-4H-1-benzopyran-4,1'-cyclohexan]-2-one derivatives by reaction sequences including a radical reaction and a total synthesis of (±)-lycoramine (2) are described. Radical reactions (Bu 3 SnH, AIBN) of 1-[(1'-cyclohexenylmethyl)oxy]-2-halobenzenes 23b-d in boiling benzene gave the corresponding spiro[2,3-dihydrobenzofuran-3,1'-cyclohexanes] 26a,b in good yields, whereas the reaction of 1-(1'-cyclohexenylethoxy)-2-bromobenzene (25) under similar conditions afforded a mixture of spiro[2,3-dihydro-4H-1-benzopyran-4,1'-cyclohexane] 27 and benzoxepin 28. Furthermore, the radical reaction of ethyl 2-[(2'-bromoaryl)oxy]-1-cyclohexenylacetate 37a produced ethyl 2-spiro[2,3-dihydrobenzofuran-3,1'-cycloexane]carboxylate 38 in good yield. Compound 38 was converted to spiro[2,3-dihydro-4H-1-benzopyran-4,1'-cyclohexane]-2,4'-dione 40 by treatment with SmI 2 and then with 3 N HCl. Spiro[2,3-dihydro-4H-1-benzopyran-4,1'-cyclohexane]-2,4'-dione 40 was transformed to (±)-lycoramine (2) in four steps in 43% overall yield" @default.
- W1973457876 created "2016-06-24" @default.
- W1973457876 creator A5007113919 @default.
- W1973457876 creator A5015881778 @default.
- W1973457876 creator A5033622691 @default.
- W1973457876 creator A5051283821 @default.
- W1973457876 creator A5079700968 @default.
- W1973457876 date "2010-08-20" @default.
- W1973457876 modified "2023-09-23" @default.
- W1973457876 title "ChemInform Abstract: Synthetic Approaches Toward Spiro(2,3-dihydro-4H-1-benzopyran-4,1′- cyclohexan)-2-one Derivatives via Radical Reactions: Total Synthesis of (.+-.)-Lycoramine." @default.
- W1973457876 cites W2950930778 @default.
- W1973457876 doi "https://doi.org/10.1002/chin.199345287" @default.
- W1973457876 hasPublicationYear "2010" @default.
- W1973457876 type Work @default.
- W1973457876 sameAs 1973457876 @default.
- W1973457876 citedByCount "0" @default.
- W1973457876 crossrefType "journal-article" @default.
- W1973457876 hasAuthorship W1973457876A5007113919 @default.
- W1973457876 hasAuthorship W1973457876A5015881778 @default.
- W1973457876 hasAuthorship W1973457876A5033622691 @default.
- W1973457876 hasAuthorship W1973457876A5051283821 @default.
- W1973457876 hasAuthorship W1973457876A5079700968 @default.
- W1973457876 hasConcept C134121241 @default.
- W1973457876 hasConcept C155647269 @default.
- W1973457876 hasConcept C161790260 @default.
- W1973457876 hasConcept C178790620 @default.
- W1973457876 hasConcept C185592680 @default.
- W1973457876 hasConcept C191897082 @default.
- W1973457876 hasConcept C192562407 @default.
- W1973457876 hasConcept C20327893 @default.
- W1973457876 hasConcept C2776286485 @default.
- W1973457876 hasConcept C2776946247 @default.
- W1973457876 hasConcept C2777691172 @default.
- W1973457876 hasConcept C2778237882 @default.
- W1973457876 hasConcept C2910947881 @default.
- W1973457876 hasConceptScore W1973457876C134121241 @default.
- W1973457876 hasConceptScore W1973457876C155647269 @default.
- W1973457876 hasConceptScore W1973457876C161790260 @default.
- W1973457876 hasConceptScore W1973457876C178790620 @default.
- W1973457876 hasConceptScore W1973457876C185592680 @default.
- W1973457876 hasConceptScore W1973457876C191897082 @default.
- W1973457876 hasConceptScore W1973457876C192562407 @default.
- W1973457876 hasConceptScore W1973457876C20327893 @default.
- W1973457876 hasConceptScore W1973457876C2776286485 @default.
- W1973457876 hasConceptScore W1973457876C2776946247 @default.
- W1973457876 hasConceptScore W1973457876C2777691172 @default.
- W1973457876 hasConceptScore W1973457876C2778237882 @default.
- W1973457876 hasConceptScore W1973457876C2910947881 @default.
- W1973457876 hasLocation W19734578761 @default.
- W1973457876 hasOpenAccess W1973457876 @default.
- W1973457876 hasPrimaryLocation W19734578761 @default.
- W1973457876 isParatext "false" @default.
- W1973457876 isRetracted "false" @default.
- W1973457876 magId "1973457876" @default.
- W1973457876 workType "article" @default.