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- W1973473202 abstract "Gastric cancer is believed to result in part from the accumulation of multiple genetic alterations leading to oncogene overexpression and tumor suppressor loss. Epigenetic alterations as a distinct and crucial mechanism to silence a variety of methylated tissue-specific and imprinted genes, have been extensively studied in gastric carcinoma and play important roles in gastric carcinogenesis. This review will briefly discuss the basic aspects of DNA methylation and CpG island methylation, in particular the epigenetic alterations of certain critical genes implicated in gastric carcinogenesis and its relevance of clinical implications." @default.
- W1973473202 created "2016-06-24" @default.
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- W1973473202 date "2005-04-01" @default.
- W1973473202 modified "2023-10-06" @default.
- W1973473202 title "Epigenetic alterations in gastric carcinogenesis" @default.
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- W1973473202 doi "https://doi.org/10.1038/sj.cr.7290293" @default.
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