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- W1973488293 abstract "The prognosis of patients with left ventricular hypertrabeculation/noncompaction (LVHT) is controversial. LVHT is associated with neuromuscular disorders (NMD) and diagnosed echocardiographically in in- as well as outpatients. We compared cardiologic and neurologic findings and mortality in LVHT-patients according to their diagnosis established as in- or outpatients.Among 113 patients (33 females, mean-age 53 years), 91 were investigated neurologically. Fifty-nine inpatients were older (55 versus 50 years, p<0.05), more frequently referred because of heart failure (73 versus 37%, p<0.001), had more often diabetes (24 versus 7%, p<0.05), heart failure (81 versus 57%, p<0.01), a lower left-ventricular fractional-shortening (21 versus 26%, p<0.05) and more extensive LVHT (1.7 versus 1.5 affected walls, p<0.05). Fifty-four outpatients were referred more often because of chest-pain (33 versus 12%, p<0.01), myopathy (13 versus 2%, p<0.05), were more often neurologically normal (20 versus 7%, p<0.05) or had a specific NMD (28 versus 12%, p<0.05). During a mean follow-up of 3.8 years, mortality was 5.8%/year. Inpatients had a higher mortality (12.1 versus 2.1%/year, p=0.0002) and a shorter time between LVHT-diagnosis and death (1.7 versus 4.6 years, p=0.0197) than outpatients.Outpatients with LVHT have a better prognosis than inpatients. Inpatients with LVHT should be closely monitored." @default.
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- W1973488293 date "2010-04-01" @default.
- W1973488293 modified "2023-09-27" @default.
- W1973488293 title "In- and outpatients with noncompaction: Differences in cardiac and neuromuscular co-morbidity" @default.
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- W1973488293 doi "https://doi.org/10.1016/j.ijcard.2008.10.041" @default.
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