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- W1973541034 abstract "The effect of protein restriction on the growth of muscle, bone and body tissue of rats fed a diet containing 5% protein (experimental group) and 12% protein (control group) was studied. The following parameters were analyzed: body, muscle and cartilage growth, tibial length, plasma insulin IGF-1 concentrations, and tissue proteoglycan, protein, RNA and insulin-like growth factor-1 concentrations. Protein synthesis in tissues was also determined. Except for protein concentration in the two tissues and of insulin-like growth factor-1 in cartilage, all other values differed significantly between groups. The lower ration and protein ingestion by group 1 receiving a 5% case in diet provoked a reduced secretion of the anabolic hormones insulin and IGF-1 and a lower synthesis of proteoglycans, RNA and protein, impairing total body growth and growth of the tissues analyzed." @default.
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- W1973541034 date "1999-01-01" @default.
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- W1973541034 title "Effect of insulin-like growth factor-1 (IGF-1) on muscle and bone growth in experimental models" @default.
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- W1973541034 doi "https://doi.org/10.1080/096374899101102" @default.
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