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- W1973543095 abstract "Temporary denervation of the medial head of gastrocnemius muscle in newborn rats has produced three major changes in muscle spindle development: (1) a modification of the spindles' components, (2) an increase or decrease in the number of spindles that developed in the experimental muscles and (3) an alteration in the location of spindles. The most striking change was observed in a total of 15 spindles from three of the experimental animals and consisted of a modification of the components. The abnormal, modified spindles usually contained only one muscle fiber, which had the morphological characteristics of an intrafusal fiber at one end and in the equatorial zone, and the morphological characteristics of an extrafusal fiber at the opposite end. These peculiar muscle fibers clearly represent a single cell which has differentiated along two distinctly different pathways and they show that the pattern of innervation can influence the course of differentiation of developing muscle cells to a significant extent." @default.
- W1973543095 created "2016-06-24" @default.
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- W1973543095 date "1973-08-01" @default.
- W1973543095 modified "2023-10-17" @default.
- W1973543095 title "Mixed intra- and extrafusal muscle fibers produced by temporary denervation in newborn rats" @default.
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- W1973543095 doi "https://doi.org/10.1002/cne.901500304" @default.
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