Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973553436> ?p ?o ?g. }
- W1973553436 endingPage "197" @default.
- W1973553436 startingPage "191" @default.
- W1973553436 abstract "The effects of fasciolosis on drug disposition were studied by administration of antipyrine, erythromycin and oxytetracycline to sheep and cattle. Fasciolosis was produced by administration of 200 or 400 metacercariae (MC) of Fasciola hepatica to sheep and 500 MC to cattle. The disease was subsequently confirmed by determination of plasma glutamate dehydrogenase and gamma-glutamyl transferase and identification and quantitation of mature flukes in the liver at necropsy. Acute or subacute fasciolosis in sheep was accompanied by a significant decrease in the elimination rate constant (beta) and increase in the elimination half-time (t 1/2) for antipyrine and erythromycin when compared with controls or infected sheep which had been treated with the anthelmintic luxabendazole. An increase in apparent volume of distribution (Vd) was seen only for erythromycin in sheep given 400 MC. There were no changes in the disposition of oxytetracycline in sheep with either acute or subacute infection and no effects on disposition of the three test drugs in chronically infected sheep. With early chronic disease in calves, only the disposition of oxytetracycline was affected; not that of antipyrine or erythromycin." @default.
- W1973553436 created "2016-06-24" @default.
- W1973553436 creator A5029357529 @default.
- W1973553436 creator A5033787136 @default.
- W1973553436 creator A5033827839 @default.
- W1973553436 creator A5091568146 @default.
- W1973553436 date "1992-09-01" @default.
- W1973553436 modified "2023-09-27" @default.
- W1973553436 title "Antipyrine, erythromycin and oxytetracycline disposition in experimental fasciolosis" @default.
- W1973553436 cites W11096788 @default.
- W1973553436 cites W137943138 @default.
- W1973553436 cites W1965147265 @default.
- W1973553436 cites W1989880043 @default.
- W1973553436 cites W1994420004 @default.
- W1973553436 cites W1997855734 @default.
- W1973553436 cites W2001233384 @default.
- W1973553436 cites W2018934346 @default.
- W1973553436 cites W2027571613 @default.
- W1973553436 cites W2063556633 @default.
- W1973553436 cites W2081215869 @default.
- W1973553436 cites W2082717179 @default.
- W1973553436 cites W2147856655 @default.
- W1973553436 cites W2394597293 @default.
- W1973553436 cites W2404816176 @default.
- W1973553436 cites W2409853743 @default.
- W1973553436 cites W4231803579 @default.
- W1973553436 cites W4252032354 @default.
- W1973553436 cites W50277004 @default.
- W1973553436 doi "https://doi.org/10.1016/0034-5288(92)90109-f" @default.
- W1973553436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1439209" @default.
- W1973553436 hasPublicationYear "1992" @default.
- W1973553436 type Work @default.
- W1973553436 sameAs 1973553436 @default.
- W1973553436 citedByCount "4" @default.
- W1973553436 countsByYear W19735534362012 @default.
- W1973553436 crossrefType "journal-article" @default.
- W1973553436 hasAuthorship W1973553436A5029357529 @default.
- W1973553436 hasAuthorship W1973553436A5033787136 @default.
- W1973553436 hasAuthorship W1973553436A5033827839 @default.
- W1973553436 hasAuthorship W1973553436A5091568146 @default.
- W1973553436 hasConcept C112705442 @default.
- W1973553436 hasConcept C126322002 @default.
- W1973553436 hasConcept C139254425 @default.
- W1973553436 hasConcept C15744967 @default.
- W1973553436 hasConcept C165901193 @default.
- W1973553436 hasConcept C203014093 @default.
- W1973553436 hasConcept C2776671240 @default.
- W1973553436 hasConcept C2776908094 @default.
- W1973553436 hasConcept C2777056448 @default.
- W1973553436 hasConcept C2777226933 @default.
- W1973553436 hasConcept C2777856171 @default.
- W1973553436 hasConcept C2777861111 @default.
- W1973553436 hasConcept C2780206985 @default.
- W1973553436 hasConcept C38022665 @default.
- W1973553436 hasConcept C42972112 @default.
- W1973553436 hasConcept C501593827 @default.
- W1973553436 hasConcept C71924100 @default.
- W1973553436 hasConcept C77805123 @default.
- W1973553436 hasConcept C86803240 @default.
- W1973553436 hasConcept C89423630 @default.
- W1973553436 hasConcept C98274493 @default.
- W1973553436 hasConceptScore W1973553436C112705442 @default.
- W1973553436 hasConceptScore W1973553436C126322002 @default.
- W1973553436 hasConceptScore W1973553436C139254425 @default.
- W1973553436 hasConceptScore W1973553436C15744967 @default.
- W1973553436 hasConceptScore W1973553436C165901193 @default.
- W1973553436 hasConceptScore W1973553436C203014093 @default.
- W1973553436 hasConceptScore W1973553436C2776671240 @default.
- W1973553436 hasConceptScore W1973553436C2776908094 @default.
- W1973553436 hasConceptScore W1973553436C2777056448 @default.
- W1973553436 hasConceptScore W1973553436C2777226933 @default.
- W1973553436 hasConceptScore W1973553436C2777856171 @default.
- W1973553436 hasConceptScore W1973553436C2777861111 @default.
- W1973553436 hasConceptScore W1973553436C2780206985 @default.
- W1973553436 hasConceptScore W1973553436C38022665 @default.
- W1973553436 hasConceptScore W1973553436C42972112 @default.
- W1973553436 hasConceptScore W1973553436C501593827 @default.
- W1973553436 hasConceptScore W1973553436C71924100 @default.
- W1973553436 hasConceptScore W1973553436C77805123 @default.
- W1973553436 hasConceptScore W1973553436C86803240 @default.
- W1973553436 hasConceptScore W1973553436C89423630 @default.
- W1973553436 hasConceptScore W1973553436C98274493 @default.
- W1973553436 hasIssue "2" @default.
- W1973553436 hasLocation W19735534361 @default.
- W1973553436 hasLocation W19735534362 @default.
- W1973553436 hasOpenAccess W1973553436 @default.
- W1973553436 hasPrimaryLocation W19735534361 @default.
- W1973553436 hasRelatedWork W1973553436 @default.
- W1973553436 hasRelatedWork W2010929939 @default.
- W1973553436 hasRelatedWork W2023580981 @default.
- W1973553436 hasRelatedWork W2043135819 @default.
- W1973553436 hasRelatedWork W2053412561 @default.
- W1973553436 hasRelatedWork W2054552425 @default.
- W1973553436 hasRelatedWork W2073827333 @default.
- W1973553436 hasRelatedWork W2463077557 @default.
- W1973553436 hasRelatedWork W2908973926 @default.
- W1973553436 hasRelatedWork W3046041015 @default.
- W1973553436 hasVolume "53" @default.