FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973566996> ?p ?o ?g. }

• W1973566996 endingPage "244" @default.
• W1973566996 startingPage "241" @default.
• W1973566996 abstract "Inositol phosphorylceramide synthase (IPC synthase) is an essential and unique enzyme in fungal sphingolipid biosynthesis and is the target of the cyclic nonadepsipeptide antibiotic aureobasidin A. As a first step towards understanding the mechanism of aureobasidin A inhibition, we developed a fluorometric HPLC assay for IPC synthase using the Saccharomyces cerevisiae enzyme and the fluorescent substrate analog 6‐[ N ‐(7‐nitro‐2,1,3‐benzoxadiazol‐4‐yl)amino]‐hexanoyl ceramide (C 6 ‐NBD‐cer). The kinetic parameters for C 6 ‐NBD‐cer were comparable to those for the synthetic substrate N ‐acetylsphinganine used previously. Aureobasidin A acted as a tight‐binding, non‐competitive inhibitor with respect to C 6 ‐NBD‐cer and had a K i of 0.55 nM." @default.
• W1973566996 created "2016-06-24" @default.
• W1973566996 creator A5010555054 @default.
• W1973566996 creator A5023943851 @default.
• W1973566996 creator A5038089319 @default.
• W1973566996 date "1999-12-17" @default.
• W1973566996 modified "2023-10-06" @default.
• W1973566996 title "Inhibition of yeast inositol phosphorylceramide synthase by aureobasidin A measured by a fluorometric assay" @default.
• W1973566996 cites W1602150101 @default.
• W1973566996 cites W1975588858 @default.
• W1973566996 cites W1998083138 @default.
• W1973566996 cites W2007759229 @default.
• W1973566996 cites W2023062382 @default.
• W1973566996 cites W2024404351 @default.
• W1973566996 cites W2028419688 @default.
• W1973566996 cites W2028652974 @default.
• W1973566996 cites W2030063540 @default.
• W1973566996 cites W2066160116 @default.
• W1973566996 cites W2066649831 @default.
• W1973566996 cites W2077451485 @default.
• W1973566996 cites W2097801957 @default.
• W1973566996 cites W2099521932 @default.
• W1973566996 cites W2112173514 @default.
• W1973566996 cites W2138563960 @default.
• W1973566996 cites W2210033643 @default.
• W1973566996 cites W2312591113 @default.
• W1973566996 doi "https://doi.org/10.1016/s0014-5793(99)01633-6" @default.
• W1973566996 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10606729" @default.
• W1973566996 hasPublicationYear "1999" @default.
• W1973566996 type Work @default.
• W1973566996 sameAs 1973566996 @default.
• W1973566996 citedByCount "32" @default.
• W1973566996 countsByYear W19735669962015 @default.
• W1973566996 countsByYear W19735669962016 @default.
• W1973566996 countsByYear W19735669962018 @default.
• W1973566996 countsByYear W19735669962019 @default.
• W1973566996 countsByYear W19735669962021 @default.
• W1973566996 crossrefType "journal-article" @default.
• W1973566996 hasAuthorship W1973566996A5010555054 @default.
• W1973566996 hasAuthorship W1973566996A5023943851 @default.
• W1973566996 hasAuthorship W1973566996A5038089319 @default.
• W1973566996 hasBestOaLocation W19735669961 @default.
• W1973566996 hasConcept C112243037 @default.
• W1973566996 hasConcept C121332964 @default.
• W1973566996 hasConcept C150757390 @default.
• W1973566996 hasConcept C170493617 @default.
• W1973566996 hasConcept C181199279 @default.
• W1973566996 hasConcept C185592680 @default.
• W1973566996 hasConcept C18903297 @default.
• W1973566996 hasConcept C190283241 @default.
• W1973566996 hasConcept C2777289219 @default.
• W1973566996 hasConcept C2777427919 @default.
• W1973566996 hasConcept C2777576037 @default.
• W1973566996 hasConcept C2777851122 @default.
• W1973566996 hasConcept C2779222958 @default.
• W1973566996 hasConcept C553450214 @default.
• W1973566996 hasConcept C55493867 @default.
• W1973566996 hasConcept C61705674 @default.
• W1973566996 hasConcept C62520636 @default.
• W1973566996 hasConcept C71240020 @default.
• W1973566996 hasConcept C86803240 @default.
• W1973566996 hasConcept C91881484 @default.
• W1973566996 hasConceptScore W1973566996C112243037 @default.
• W1973566996 hasConceptScore W1973566996C121332964 @default.
• W1973566996 hasConceptScore W1973566996C150757390 @default.
• W1973566996 hasConceptScore W1973566996C170493617 @default.
• W1973566996 hasConceptScore W1973566996C181199279 @default.
• W1973566996 hasConceptScore W1973566996C185592680 @default.
• W1973566996 hasConceptScore W1973566996C18903297 @default.
• W1973566996 hasConceptScore W1973566996C190283241 @default.
• W1973566996 hasConceptScore W1973566996C2777289219 @default.
• W1973566996 hasConceptScore W1973566996C2777427919 @default.
• W1973566996 hasConceptScore W1973566996C2777576037 @default.
• W1973566996 hasConceptScore W1973566996C2777851122 @default.
• W1973566996 hasConceptScore W1973566996C2779222958 @default.
• W1973566996 hasConceptScore W1973566996C553450214 @default.
• W1973566996 hasConceptScore W1973566996C55493867 @default.
• W1973566996 hasConceptScore W1973566996C61705674 @default.
• W1973566996 hasConceptScore W1973566996C62520636 @default.
• W1973566996 hasConceptScore W1973566996C71240020 @default.
• W1973566996 hasConceptScore W1973566996C86803240 @default.
• W1973566996 hasConceptScore W1973566996C91881484 @default.
• W1973566996 hasIssue "3" @default.
• W1973566996 hasLocation W19735669961 @default.
• W1973566996 hasLocation W19735669962 @default.
• W1973566996 hasOpenAccess W1973566996 @default.
• W1973566996 hasPrimaryLocation W19735669961 @default.
• W1973566996 hasRelatedWork W171603164 @default.
• W1973566996 hasRelatedWork W1967097207 @default.
• W1973566996 hasRelatedWork W1984675230 @default.
• W1973566996 hasRelatedWork W2020166917 @default.
• W1973566996 hasRelatedWork W2049260737 @default.
• W1973566996 hasRelatedWork W2085982495 @default.
• W1973566996 hasRelatedWork W2316508949 @default.
• W1973566996 hasRelatedWork W2395087597 @default.
• W1973566996 hasRelatedWork W2885900514 @default.
• W1973566996 hasRelatedWork W2925386497 @default.
• W1973566996 hasVolume "463" @default.

• next