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- W1973600161 abstract "Propylthiouracil fed to pregnant rats for the last week of gestation to induce maternal and fetal hypothyroidism induced a 3-fold rise in plasma TSH concentration in the newborn pups compared to a 4-fold rise in their mothers. Subcutaneous administration of 1 ng/g BW TRH caused a greater rise in plasma TSH in the hypothyroid pups than in their mothers. These results, in combination with published data, indicate that the apparent independence of pituitary-thyroid function from TRH control during early ontogenesis in the rat is primarily due to delayed maturation of the hypothalamic TRH system." @default.
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- W1973600161 date "1981-04-01" @default.
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- W1973600161 title "Thyrotropin Secretory Response to Thyrotropin-Releasing Hormone in the Hypothyroid Perinatal Rat: Further Evidence of Thyrotroph Independence of the Hypothalamus during Early Ontogenesis*" @default.
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- W1973600161 doi "https://doi.org/10.1210/endo-108-4-1403" @default.
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