FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973603016> ?p ?o ?g. }

• W1973603016 endingPage "183" @default.
• W1973603016 startingPage "175" @default.
• W1973603016 abstract "Study Objective. To assess the pharmacokinetics of levofloxacin during continuous venovenous hemodiafiltration (CVVHDF) and continuous venovenous hemofiltration (CVVH). Design. Nonrandomized pharmacokinetic evaluation. Setting. University surgical intensive care unit. Patients. Six critically ill patients. Intervention. Five patients received levofloxacin 500 mg/day and one patient received levofloxacin 125 mg/day. All patients received continuous renal replacement therapy: CVVHDF on day 1 and CVVH on day 2, using an acrylonitrile hollow-fiber 0.9-m2 filter, constant blood flow rate of 90 ml/minute, substitution flow rate of 1 L/hour predilution, and dialysate flow rate of 1 L/hour (CVVHDF). Measurements and Main Results. Serum, ultrafiltrate, and dialysate concentrations of levofloxacin were determined by high-performance liquid chromatography. Extracorporeal clearance was 26.05 ± 4.66 ml/hour during CVVHDF and 15.71 ± 2.73 ml/hour during CVVH (p<0.05). Elimination half-life was 28.08 ± 4.5 hours and 45.9 ± 17.7 hours, and distribution volume was 1.51 ± 0.52 L/kg and 1.42 ± 0.42 L/kg for CVVHDF and CVVH, respectively. Saturation was 0.76 ± 0.13 for CVVHDF versus a sieving coefficient of 0.77 ± 0.16 for CVVH. Conclusion. Marked extracorporeal elimination of levofloxacin occurs, requiring a dosage adjustment that can be calculated from the characteristics of CVVH and CVVHDF." @default.
• W1973603016 created "2016-06-24" @default.
• W1973603016 creator A5004081013 @default.
• W1973603016 creator A5013994650 @default.
• W1973603016 creator A5038296267 @default.
• W1973603016 creator A5040678599 @default.
• W1973603016 creator A5080843747 @default.
• W1973603016 date "2002-02-01" @default.
• W1973603016 modified "2023-09-27" @default.
• W1973603016 title "Pharmacokinetics of Levofloxacin During Continuous Venovenous Hemodiafiltration and Continuous Venovenous Hemofiltration in Critically Ill Patients" @default.
• W1973603016 cites W1780896360 @default.
• W1973603016 cites W1970899202 @default.
• W1973603016 cites W1983411303 @default.
• W1973603016 cites W1995695108 @default.
• W1973603016 cites W2000173078 @default.
• W1973603016 cites W2010352340 @default.
• W1973603016 cites W2014256079 @default.
• W1973603016 cites W2015611356 @default.
• W1973603016 cites W2023309638 @default.
• W1973603016 cites W2024738609 @default.
• W1973603016 cites W2039355480 @default.
• W1973603016 cites W2041206825 @default.
• W1973603016 cites W2041909146 @default.
• W1973603016 cites W2044835967 @default.
• W1973603016 cites W2052329293 @default.
• W1973603016 cites W2054772937 @default.
• W1973603016 cites W2069598059 @default.
• W1973603016 cites W2086291756 @default.
• W1973603016 cites W2089087883 @default.
• W1973603016 cites W2097776950 @default.
• W1973603016 cites W2107778172 @default.
• W1973603016 cites W2148973700 @default.
• W1973603016 cites W2270721561 @default.
• W1973603016 cites W2330561848 @default.
• W1973603016 doi "https://doi.org/10.1592/phco.22.3.175.33546" @default.
• W1973603016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11837556" @default.
• W1973603016 hasPublicationYear "2002" @default.
• W1973603016 type Work @default.
• W1973603016 sameAs 1973603016 @default.
• W1973603016 citedByCount "33" @default.
• W1973603016 countsByYear W19736030162012 @default.
• W1973603016 countsByYear W19736030162016 @default.
• W1973603016 countsByYear W19736030162017 @default.
• W1973603016 countsByYear W19736030162018 @default.
• W1973603016 countsByYear W19736030162019 @default.
• W1973603016 countsByYear W19736030162020 @default.
• W1973603016 countsByYear W19736030162021 @default.
• W1973603016 countsByYear W19736030162022 @default.
• W1973603016 crossrefType "journal-article" @default.
• W1973603016 hasAuthorship W1973603016A5004081013 @default.
• W1973603016 hasAuthorship W1973603016A5013994650 @default.
• W1973603016 hasAuthorship W1973603016A5038296267 @default.
• W1973603016 hasAuthorship W1973603016A5040678599 @default.
• W1973603016 hasAuthorship W1973603016A5080843747 @default.
• W1973603016 hasConcept C112705442 @default.
• W1973603016 hasConcept C139254425 @default.
• W1973603016 hasConcept C141071460 @default.
• W1973603016 hasConcept C192670549 @default.
• W1973603016 hasConcept C2778063415 @default.
• W1973603016 hasConcept C2778865887 @default.
• W1973603016 hasConcept C2779915274 @default.
• W1973603016 hasConcept C2781276175 @default.
• W1973603016 hasConcept C42219234 @default.
• W1973603016 hasConcept C501593827 @default.
• W1973603016 hasConcept C71924100 @default.
• W1973603016 hasConcept C86803240 @default.
• W1973603016 hasConcept C89423630 @default.
• W1973603016 hasConcept C98274493 @default.
• W1973603016 hasConceptScore W1973603016C112705442 @default.
• W1973603016 hasConceptScore W1973603016C139254425 @default.
• W1973603016 hasConceptScore W1973603016C141071460 @default.
• W1973603016 hasConceptScore W1973603016C192670549 @default.
• W1973603016 hasConceptScore W1973603016C2778063415 @default.
• W1973603016 hasConceptScore W1973603016C2778865887 @default.
• W1973603016 hasConceptScore W1973603016C2779915274 @default.
• W1973603016 hasConceptScore W1973603016C2781276175 @default.
• W1973603016 hasConceptScore W1973603016C42219234 @default.
• W1973603016 hasConceptScore W1973603016C501593827 @default.
• W1973603016 hasConceptScore W1973603016C71924100 @default.
• W1973603016 hasConceptScore W1973603016C86803240 @default.
• W1973603016 hasConceptScore W1973603016C89423630 @default.
• W1973603016 hasConceptScore W1973603016C98274493 @default.
• W1973603016 hasIssue "2" @default.
• W1973603016 hasLocation W19736030161 @default.
• W1973603016 hasLocation W19736030162 @default.
• W1973603016 hasOpenAccess W1973603016 @default.
• W1973603016 hasPrimaryLocation W19736030161 @default.
• W1973603016 hasRelatedWork W1459641852 @default.
• W1973603016 hasRelatedWork W1960976482 @default.
• W1973603016 hasRelatedWork W1973603016 @default.
• W1973603016 hasRelatedWork W2018466580 @default.
• W1973603016 hasRelatedWork W2019630629 @default.
• W1973603016 hasRelatedWork W2023697648 @default.
• W1973603016 hasRelatedWork W2095926637 @default.
• W1973603016 hasRelatedWork W2146730577 @default.
• W1973603016 hasRelatedWork W2749464292 @default.
• W1973603016 hasRelatedWork W3087997842 @default.
• W1973603016 hasVolume "22" @default.

• next