Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973613148> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1973613148 endingPage "177" @default.
- W1973613148 startingPage "160" @default.
- W1973613148 abstract "To study environmental factors controlling the growth and navigation of optic axons in the eye, grafts of retinal, optic disc, optic tectum, and floor plate tissue were transplanted into organ-cultured embryonic chick or quail eyes. The growth of axons into and out of the graft was studied in cross sections of the cultured eyes and by DiI tracing in retinal whole mounts. Based on the location and trajectory of axons and based on the quantity of axons that entered and exited the grafts, several requirements for axonal navigation were established: (1) Axonal growth is restricted to an approximately 10-microm-thick layer at the vitreal surface of the retina. (2) The retinal neuroepithelium prior to axogenesis is nonpermissive for neurite outgrowth. This nonpermissive quality is transient and recedes peripherally as the differentiation of the retina progresses. (3) Embryonic axons are able to grow into neonatal and adult retinal grafts, demonstrating that older retina remains permissive for axonal growth. (4) The trajectory of axons into and from retinal grafts that had been rotated in their peripheral-central orientation showed that the retina has an inherent polarity that permits axon growth toward and away from the optic disc, but does not allow axon growth perpendicular to this direction. This centroperipheral cue operates locally rather than by long distance. (5) The optic disc provides an exit for the axons from the retina, but has no detectable neurotropic activity. Finally, optic axons from the host retina readily enter grafts of their target tissue, the optic tectum, but few axons are able to leave tectal transplants." @default.
- W1973613148 created "2016-06-24" @default.
- W1973613148 creator A5014007420 @default.
- W1973613148 date "1996-07-01" @default.
- W1973613148 modified "2023-10-18" @default.
- W1973613148 title "Intraretinal Grafting Reveals Growth Requirements and Guidance Cues for Optic Axons in the Developing Avian Retina" @default.
- W1973613148 doi "https://doi.org/10.1006/dbio.1996.0153" @default.
- W1973613148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8660885" @default.
- W1973613148 hasPublicationYear "1996" @default.
- W1973613148 type Work @default.
- W1973613148 sameAs 1973613148 @default.
- W1973613148 citedByCount "23" @default.
- W1973613148 countsByYear W19736131482014 @default.
- W1973613148 countsByYear W19736131482019 @default.
- W1973613148 crossrefType "journal-article" @default.
- W1973613148 hasAuthorship W1973613148A5014007420 @default.
- W1973613148 hasBestOaLocation W19736131481 @default.
- W1973613148 hasConcept C104317684 @default.
- W1973613148 hasConcept C105702510 @default.
- W1973613148 hasConcept C113246987 @default.
- W1973613148 hasConcept C114696181 @default.
- W1973613148 hasConcept C127716648 @default.
- W1973613148 hasConcept C135903288 @default.
- W1973613148 hasConcept C136834591 @default.
- W1973613148 hasConcept C169760540 @default.
- W1973613148 hasConcept C200707615 @default.
- W1973613148 hasConcept C202751555 @default.
- W1973613148 hasConcept C2777093970 @default.
- W1973613148 hasConcept C2779480072 @default.
- W1973613148 hasConcept C2779530196 @default.
- W1973613148 hasConcept C2779735895 @default.
- W1973613148 hasConcept C2780827179 @default.
- W1973613148 hasConcept C2780837183 @default.
- W1973613148 hasConcept C28328180 @default.
- W1973613148 hasConcept C529278444 @default.
- W1973613148 hasConcept C552161191 @default.
- W1973613148 hasConcept C55493867 @default.
- W1973613148 hasConcept C69125201 @default.
- W1973613148 hasConcept C86803240 @default.
- W1973613148 hasConcept C95444343 @default.
- W1973613148 hasConcept C96021297 @default.
- W1973613148 hasConceptScore W1973613148C104317684 @default.
- W1973613148 hasConceptScore W1973613148C105702510 @default.
- W1973613148 hasConceptScore W1973613148C113246987 @default.
- W1973613148 hasConceptScore W1973613148C114696181 @default.
- W1973613148 hasConceptScore W1973613148C127716648 @default.
- W1973613148 hasConceptScore W1973613148C135903288 @default.
- W1973613148 hasConceptScore W1973613148C136834591 @default.
- W1973613148 hasConceptScore W1973613148C169760540 @default.
- W1973613148 hasConceptScore W1973613148C200707615 @default.
- W1973613148 hasConceptScore W1973613148C202751555 @default.
- W1973613148 hasConceptScore W1973613148C2777093970 @default.
- W1973613148 hasConceptScore W1973613148C2779480072 @default.
- W1973613148 hasConceptScore W1973613148C2779530196 @default.
- W1973613148 hasConceptScore W1973613148C2779735895 @default.
- W1973613148 hasConceptScore W1973613148C2780827179 @default.
- W1973613148 hasConceptScore W1973613148C2780837183 @default.
- W1973613148 hasConceptScore W1973613148C28328180 @default.
- W1973613148 hasConceptScore W1973613148C529278444 @default.
- W1973613148 hasConceptScore W1973613148C552161191 @default.
- W1973613148 hasConceptScore W1973613148C55493867 @default.
- W1973613148 hasConceptScore W1973613148C69125201 @default.
- W1973613148 hasConceptScore W1973613148C86803240 @default.
- W1973613148 hasConceptScore W1973613148C95444343 @default.
- W1973613148 hasConceptScore W1973613148C96021297 @default.
- W1973613148 hasIssue "1" @default.
- W1973613148 hasLocation W19736131481 @default.
- W1973613148 hasLocation W19736131482 @default.
- W1973613148 hasOpenAccess W1973613148 @default.
- W1973613148 hasPrimaryLocation W19736131481 @default.
- W1973613148 hasRelatedWork W1618814657 @default.
- W1973613148 hasRelatedWork W1973613148 @default.
- W1973613148 hasRelatedWork W2009883048 @default.
- W1973613148 hasRelatedWork W2011671545 @default.
- W1973613148 hasRelatedWork W2025766264 @default.
- W1973613148 hasRelatedWork W2068891950 @default.
- W1973613148 hasRelatedWork W2100976322 @default.
- W1973613148 hasRelatedWork W2105419803 @default.
- W1973613148 hasRelatedWork W2414185338 @default.
- W1973613148 hasRelatedWork W3199916353 @default.
- W1973613148 hasVolume "177" @default.
- W1973613148 isParatext "false" @default.
- W1973613148 isRetracted "false" @default.
- W1973613148 magId "1973613148" @default.
- W1973613148 workType "article" @default.