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- W1973621175 abstract "We report a case of AFH presenting as an asymptomatic subcutaneous nodule on the arm of a 6-year-old boy. AFH is a fibrohistiocytic tumor of intermediate malignancy. Predominantly seen in children and young adults, AFH presents as a deep dermal or subcutaneous nodule usually on the extremities. The histology is characterized by a fibrous capsule, surrounding lymphocytic infiltrate and blood-filled cystic spaces lined by flattened tumor cells. AFH cells express desmin, epithelial membrane antigen, and CD 68 in over 60% of cases; they are negative for myogenin, MYOD1, and endothelial markers. Rate of local recurrence is 2% to 20%. The metastatic rate is 1%. Management is with wide surgical excision and careful follow-up." @default.
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- W1973621175 date "2009-09-01" @default.
- W1973621175 modified "2023-09-26" @default.
- W1973621175 title "Angiomatoid Fibrous Histiocytoma in a Six-Year-Old Child" @default.
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- W1973621175 doi "https://doi.org/10.1111/j.1525-1470.2009.01007.x" @default.
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