Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973647761> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1973647761 endingPage "13" @default.
- W1973647761 startingPage "6" @default.
- W1973647761 abstract "Mammalian cells transformed with either 9,10-dimethyl-1,2-benzanthracene, SV40 or H-ras oncogene dramatically changed their ability to synthesize DNA and RNA and metabolize polyphosphate when L-glutamine was withdrawn from the growth medium or when heat shocked (growth at 42°C). Untransformed, DNA and RNA synthesis decreased by 50–80% when glutamine was withdrawn, but polyphosphate accumulated whether or not glutamine was supplied. Heat shock did not alter this response. Transformed isogenic cells responded differently; at 37°C, they decreased their synthesis of DNA and RNA if starved for glutamine, whereas at 42°C, synthesis was optimal without glutamine. Transformed cells accumulated polyphosphate at 37°C when starved for glutamine, but at 42°C, no polyphosphate accumulated. This apparent non-dependence on glutamine by transformed cells when heat shocked was found to be due to the production of glutamine from serum proteins through induction of a protease(s)." @default.
- W1973647761 created "2016-06-24" @default.
- W1973647761 creator A5059716960 @default.
- W1973647761 creator A5060293129 @default.
- W1973647761 date "1984-10-01" @default.
- W1973647761 modified "2023-10-14" @default.
- W1973647761 title "Involvement of protease in L-glutamine control of nucleic acid and polyphosphate metabolism in cells transformed by 9,10-dimethyl-1,2-benzanthracene, SV40 and H-ras oncogene" @default.
- W1973647761 cites W120138715 @default.
- W1973647761 cites W120353382 @default.
- W1973647761 cites W1479276714 @default.
- W1973647761 cites W1483212110 @default.
- W1973647761 cites W1606959026 @default.
- W1973647761 cites W1989145540 @default.
- W1973647761 cites W1999778948 @default.
- W1973647761 cites W2014604194 @default.
- W1973647761 cites W2030926326 @default.
- W1973647761 cites W2047064632 @default.
- W1973647761 cites W2047985797 @default.
- W1973647761 cites W2053093811 @default.
- W1973647761 cites W2075636558 @default.
- W1973647761 cites W2077484102 @default.
- W1973647761 cites W2081697199 @default.
- W1973647761 cites W2084813070 @default.
- W1973647761 cites W2105535255 @default.
- W1973647761 cites W2132147847 @default.
- W1973647761 cites W2133320565 @default.
- W1973647761 cites W2139947086 @default.
- W1973647761 cites W2157719515 @default.
- W1973647761 cites W2165446716 @default.
- W1973647761 cites W2193203205 @default.
- W1973647761 cites W2412900793 @default.
- W1973647761 doi "https://doi.org/10.1016/0006-291x(84)90908-2" @default.
- W1973647761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6093791" @default.
- W1973647761 hasPublicationYear "1984" @default.
- W1973647761 type Work @default.
- W1973647761 sameAs 1973647761 @default.
- W1973647761 citedByCount "0" @default.
- W1973647761 crossrefType "journal-article" @default.
- W1973647761 hasAuthorship W1973647761A5059716960 @default.
- W1973647761 hasAuthorship W1973647761A5060293129 @default.
- W1973647761 hasConcept C104317684 @default.
- W1973647761 hasConcept C153911025 @default.
- W1973647761 hasConcept C181199279 @default.
- W1973647761 hasConcept C185592680 @default.
- W1973647761 hasConcept C24107716 @default.
- W1973647761 hasConcept C2776714187 @default.
- W1973647761 hasConcept C2777132085 @default.
- W1973647761 hasConcept C2778038992 @default.
- W1973647761 hasConcept C2779349466 @default.
- W1973647761 hasConcept C3675279 @default.
- W1973647761 hasConcept C515207424 @default.
- W1973647761 hasConcept C552990157 @default.
- W1973647761 hasConcept C55493867 @default.
- W1973647761 hasConcept C62231903 @default.
- W1973647761 hasConcept C64241487 @default.
- W1973647761 hasConcept C67705224 @default.
- W1973647761 hasConcept C86803240 @default.
- W1973647761 hasConceptScore W1973647761C104317684 @default.
- W1973647761 hasConceptScore W1973647761C153911025 @default.
- W1973647761 hasConceptScore W1973647761C181199279 @default.
- W1973647761 hasConceptScore W1973647761C185592680 @default.
- W1973647761 hasConceptScore W1973647761C24107716 @default.
- W1973647761 hasConceptScore W1973647761C2776714187 @default.
- W1973647761 hasConceptScore W1973647761C2777132085 @default.
- W1973647761 hasConceptScore W1973647761C2778038992 @default.
- W1973647761 hasConceptScore W1973647761C2779349466 @default.
- W1973647761 hasConceptScore W1973647761C3675279 @default.
- W1973647761 hasConceptScore W1973647761C515207424 @default.
- W1973647761 hasConceptScore W1973647761C552990157 @default.
- W1973647761 hasConceptScore W1973647761C55493867 @default.
- W1973647761 hasConceptScore W1973647761C62231903 @default.
- W1973647761 hasConceptScore W1973647761C64241487 @default.
- W1973647761 hasConceptScore W1973647761C67705224 @default.
- W1973647761 hasConceptScore W1973647761C86803240 @default.
- W1973647761 hasIssue "1" @default.
- W1973647761 hasLocation W19736477611 @default.
- W1973647761 hasLocation W19736477612 @default.
- W1973647761 hasOpenAccess W1973647761 @default.
- W1973647761 hasPrimaryLocation W19736477611 @default.
- W1973647761 hasRelatedWork W1647073173 @default.
- W1973647761 hasRelatedWork W1973390003 @default.
- W1973647761 hasRelatedWork W2024495317 @default.
- W1973647761 hasRelatedWork W2033749589 @default.
- W1973647761 hasRelatedWork W2055811955 @default.
- W1973647761 hasRelatedWork W2072763201 @default.
- W1973647761 hasRelatedWork W2110427609 @default.
- W1973647761 hasRelatedWork W2130841177 @default.
- W1973647761 hasRelatedWork W2159838068 @default.
- W1973647761 hasRelatedWork W2412697889 @default.
- W1973647761 hasVolume "124" @default.
- W1973647761 isParatext "false" @default.
- W1973647761 isRetracted "false" @default.
- W1973647761 magId "1973647761" @default.
- W1973647761 workType "article" @default.